Development and Internal Validation of an AI-Enabled Cuff-less, Non-invasive Continuous Blood Pressure Monitor Across All Classes of Hypertension [0.03%]
无创连续血压监测人工智能算法的开发和内部验证：涵盖所有高血压分期
Francisco Lopez-Jimenez,Abhishek Deshmukh,John Bisognano et al.
Francisco Lopez-Jimenez et al.
Background: Non-invasive, continuous blood pressure monitoring technologies require additional validation beyond standard cuff-based methods. This study evaluates a non-invasive, multiparametric wearable cuffless blood pr...
Long Non-Coding RNAs in Diabetic Cardiomyopathy: Potential Function as Biomarkers and Therapeutic Targets of Exercise Training [0.03%]
糖尿病心肌病中长链非编码RNA的潜在作用：运动训练生物标志物和治疗靶点的功能
Jie Hu,Xinwen Miao,Li-Hua Yu
Jie Hu
Recent studies emphasize the beneficial effects of exercise on diabetic cardiomyopathy (DCM), adding to the growing body of evidence that underscores the role of exercise in improving health outcomes. Despite this, a notable gap persists in...
Senescence-related Genes as Prognostic Markers for STEMI Patients: LASSO Regression-Based Bioinformatics and External Validation [0.03%]
基于LASSO回归的生物信息学和外部验证发现与STEMI患者预后相关的衰老基因标志物
Xing-Jie Wang,Lei Huang,Min Hou et al.
Xing-Jie Wang et al.
The prognostic value of differentially expressed senescence-related genes(DESRGs) in ST-segment elevation myocardial infarction(STEMI) patients is unclear. We used GEO2R to identify DESRGs from GSE60993 and performed functional enrichment a...
Bufalin Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Macrophage Pyroptosis via P62 Pathway [0.03%]
白桦脂醇通过P62信号通路抑制巨噬细胞焦亡改善心肌缺血再灌注损伤
Chang Li,Zhen Ma,Xiang Wei et al.
Chang Li et al.
Bufalin, which is isolated from toad venom, exerts positive effects on hearts under pathological circumstance. We aimed to investigate the effects and mechanisms of bufalin on myocardial I/R injury. In vivo, bufalin ameliorated myocardial I...
Diagnostic Value and Short-Term Prognosis Assessment of Copeptin in Non-ST-Elevation Acute Coronary Syndrome [0.03%]
copeptin在非ST段抬高型急性冠脉综合征诊断及短期预后评估中的价值
Facai Cui,Xueliang Pei,Mingzhi Ling et al.
Facai Cui et al.
This study explored the early diagnosis and prognostic value of copeptin in non-ST-segment elevation acute coronary syndrome (NSTE-ACS). 171 patients with chest pain or myocardial ischemia symptoms were enrolled. Patients with NSTE-ACS were...
Correction: AIM2 Deficiency Alleviates Cardiac Inflammation and Hypertrophy in HFD/STZ-Induced Diabetic Mice by Inhibiting the NLRC4/IRF1 Signaling Pathway [0.03%]
纠正：AIM2缺乏通过抑制NLRC4/IRF1信号通路缓解高脂饮食/链脲佐菌素诱导的糖尿病小鼠心脏炎症和肥大
Jian-Ping Wu,Cheng Wu,Yuan-Ji Ma et al.
Jian-Ping Wu et al.
Machine Learning Model for Risk Prediction of Prolonged Intensive Care Unit in Patients Receiving Intra-aortic Balloon Pump Therapy during Coronary Artery Bypass Graft Surgery [0.03%]
冠状动脉旁路移植术期间主动脉内球囊泵治疗患者的重症监护时间延长的风险预测的机器学习模型
Changqing Yang,Peng Zheng,Qian Zhang et al.
Changqing Yang et al.
This study aimed to construct machine learning models and predict prolonged intensive care units (ICU) stay in patients receiving perioperative intra-aortic balloon pump (IABP) therapy during cardiac surgery. 236 patients were divided into ...
NAT10 Modulates Atherosclerosis Progression Mediated by Macrophage Polarization Through Regulating ac4C Modification of TLR9 [0.03%]
NAT10通过调控TLR9的ac4C修饰调节巨噬细胞极化介导动脉粥样硬化进展
Wei Yin,Jie Wang,Lingling Li et al.
Wei Yin et al.
Atherosclerosis (AS) is an inflammatory disease affected by macrophage polarization. N4-acetylcytosine (ac4C) modification mediated by N-acetyltransferase 10 (NAT10). In this study, we aimed to elucidate the role of ac4C modification mediat...
Associations of Blood Lipid-Related Polygenic Scores, Lifestyle Factors and Their Combined Effects with Risk of Coronary Artery Disease in the UK Biobank Cohort [0.03%]
基于英国生物样本库队列的血脂多基因评分、生活方式因素及其联合作用与冠心病风险的相关性研究
Jungyoon Choi,Wanqing Wen,Guochong Jia et al.
Jungyoon Choi et al.
Circulating lipids play a crucial role in the development of coronary artery disease (CAD). However, it is unclear whether the genetic susceptibility to hyperlipidemia may interact with lifestyle factors in CAD risk. Using UK Biobank data f...
Prediction of Major Adverse Limb Events in Females with Peripheral Artery Disease using Blood-Based Biomarkers and Clinical Features [0.03%]
基于血液生物标志物和临床特征预测外周动脉疾病女性患者的重大不良下肢事件
Ben Li,Hamzah Khan,Farah Shaikh et al.
Ben Li et al.
The objective of this study was to identify a female-specific prognostic biomarker for peripheral artery disease (PAD) and develop a prediction model for 2-year major adverse limb events (MALE). Patients with/without PAD were recruited (n=4...