Soluble ST2 and Risk of Arrhythmias, Heart Failure, or Death in Patients with Mildly Symptomatic Heart Failure: Results from MADIT-CRT [0.03%]
可溶性ST2与轻度症状性心力衰竭患者的心律失常、心力衰竭或死亡风险的关系：MADIT-CRT研究结果
Hicham Skali,Robert Gerwien,Timothy E Meyer et al.
Hicham Skali et al.
Soluble ST2 is an established biomarker of heart failure (HF) progression. Data about its prognostic implications in patients with mildly symptomatic HF eligible to receive cardiac resynchronization therapy defibrillators (CRT-D) are limite...
Randomized Controlled Trial
Journal of cardiovascular translational research. 2016 Dec;9(5-6):421-428. DOI:10.1007/s12265-016-9713-1 2016
ST2-Based Precision Medicine in Device Management: the Next Frontier Beyond MADIT-CRT? [0.03%]
基于ST2的器械管理精准医疗：MADIT-CRT研究之后的新前沿？
Antoni Bayes-Genis
Antoni Bayes-Genis
Bioresorbable Scaffolds in Cardiac Allograft Vasculopathy-Searching for the Holy Grail [0.03%]
可吸收支架在心脏移植血管病中的应用——寻找圣杯般的疗法
Luís Leite,João Silva Marques,Vítor Matos et al.
Luís Leite et al.
Reply: Bioresorbable Scaffolds in Cardiac Allograft Vasculopathy-Searching for the Holy Grail Facing the challenge of the "Perilous Seat" [0.03%]
回复：心脏同种异体移植血管病变中的生物可吸收支架-寻找“圣杯”以应对“危险席”的挑战
Michele Pighi,Fabrizio Tomai,Flavio Ribichini
Michele Pighi
Zunzhe Wang,Xing Rong,Bihui Luo et al.
Zunzhe Wang et al.
Many cardiac aging studies are performed on mice first and then, due to difficulty in mouse cardiomyocyte culture, applied the rat neonatal cardiomyocytes to further determine the mechanisms in vitro. Now, the technological challenge of mou...
Serial Echocardiographic Characteristics, Novel Biomarkers and Cachexia Development in Patients with Stable Chronic Heart Failure [0.03%]
慢性稳定性心脏病患者的系列床旁超声心动图特征、新型生物标志物和恶病质发生的关系
Hanna K Gaggin,Arianna M Belcher,Parul U Gandhi et al.
Hanna K Gaggin et al.
Little is known regarding objective predictors of cachexia affecting patients with heart failure (HF). We studied 108 stable chronic systolic HF patients with serial echocardiography and biomarker measurements over 10 months. Cachexia was d...
Randomized Controlled Trial
Journal of cardiovascular translational research. 2016 Dec;9(5-6):429-431. DOI:10.1007/s12265-016-9710-4 2016
Arne A N Bruyneel,Apurv Sehgal,Sophia Malandraki-Miller et al.
Arne A N Bruyneel et al.
When stressed by ageing or disease, the adult human heart is unable to regenerate, leading to scarring and hypertrophy and eventually heart failure. As a result, stem cell therapy has been proposed as an ultimate therapeutic strategy, as st...
Systemic Delivery of Nanoparticles Loaded with Pentagalloyl Glucose Protects Elastic Lamina and Prevents Abdominal Aortic Aneurysm in Rats [0.03%]
载五倍子素葡萄糖纳米颗粒的系统给药保护弹性纤维层并预防大鼠腹主动脉瘤
Nasim Nosoudi,Aniqa Chowdhury,Steven Siclari et al.
Nasim Nosoudi et al.
Degeneration of elastin plays a vital role in the pathology and progression of abdominal aortic aneurysm (AAA). Our previous study showed that pentagalloyl glucose (PGG), a core derivative of tannic acid, hinders the development of AAAs in ...
Bone Marrow-Derived Progenitor Cells Are Functionally Impaired in Ischemic Heart Disease [0.03%]
骨髓源性祖细胞在缺血性心脏病患者中的功能紊乱
Evelien Nollet,Vicky Y Hoymans,Inez R Rodrigus et al.
Evelien Nollet et al.
To determine whether the presence of ischemic heart disease (IHD) per se, or rather the co-presence of heart failure (HF), is the primum movens for less effective stem cell products in autologous stem cell therapy, we assessed numbers and f...
Patient-Specific Simulations Reveal Significant Differences in Mechanical Stimuli in Venous and Arterial Coronary Grafts [0.03%]
基于患者的模拟发现动静脉移植冠状动脉手术后力学刺激差异较大
Abhay B Ramachandra,Andrew M Kahn,Alison L Marsden
Abhay B Ramachandra
Mechanical stimuli are key to understanding disease progression and clinically observed differences in failure rates between arterial and venous grafts following coronary artery bypass graft surgery. We quantify biologically relevant mechan...