Platelet microRNA Expression Can Predict Bleeding in HeartMate3 Patients Treated With or Without Aspirin [0.03%]
血小板microRNA表达可预测Heartmate3患者出血风险：随机使用阿司匹林的影响
Chiara Foglieni,Davide Ravanelli,Maria Lombardi et al.
Chiara Foglieni et al.
We tested whether platelet microRNAs (miRs) expression can predict bleeding in patients supported with the HeartMate3 (HM3) left ventricular assist device (LVAD). The levels of expression of platelet miR-126, miR-233, miR-151a, and miR-454 ...
The Proteome Profile of Stress Test Assessed Cardiovascular Disease Risk-Prone Diabetic Subjects [0.03%]
糖尿病患者压力测试评估的心血管疾病风险的蛋白质组学谱型分析
Yugendra R Patil,Shalbha Tiwari,A G Unnikrishnan et al.
Yugendra R Patil et al.
Cardiovascular disease (CVD) is the leading cause of death in the diabetic population. There is a need for specific predictive markers to assess CVD risk. The present study explored the plasma proteome profile of treadmill test (TMT) assess...
Circulating miRNAs Signature as a Predictor of Cachexia in Chronic Heart Failure: Diagnostic and Prognostic Implications [0.03%]
循环miRNA谱作为慢性心力衰竭恶病质预测标志物的诊断及预后价值
Tomasz Powrózek,Marcin Mazurek,Aneta Skwarek-Dziekanowska et al.
Tomasz Powrózek et al.
Cachexia, often seen in chronic heart failure (CHF), worsens patient outcomes and survival. Early detection is crucial, and circulating miRNAs offer potential as biomarkers linking heart function, inflammation, and cachexia. This study aime...
Ferroptosis Related Serum Gpx4 Correlates to Severity of Coronary Artery Stenosis, and in-Stent Restenosis in Patients [0.03%]
血清Gpx4介导的铁死亡相关蛋白与冠状动脉狭窄及支架内再狭窄的关系研究
Xiufang Jiang,Yanling Lei,Yajuan Yin et al.
Xiufang Jiang et al.
This study aimed to explore the association between serum ferritin and glutathione peroxidase 4 (Gpx4), markers of ferroptosis, with the severity of coronary artery stenosis and the occurrence of in-stent restenosis after percutaneous coron...
Recent Insights Into Targeting Interleukin-27 in Coronary Artery Disease [0.03%]
针对冠状动脉疾病中白细胞介素-27的最新研究进展
Wei-Lin Liang,Liang Liu,Bo Liang
Wei-Lin Liang
Coronary artery disease (CAD) is increasingly recognized as a chronic inflammatory condition. Interleukin-27 (IL-27), a cytokine from the IL-12 and IL-6 families, plays a dual role in CAD pathogenesis. It exacerbates disease by interacting ...
A Molecular Perspective on the Intricate Interplay Among Exosomes, Bioenergetic Metabolism, and the Pathogenesis of Diabetic Cardiomyopathy [0.03%]
从分子角度探讨外泌体、生物能量代谢与糖尿病心肌病发病机制之间的复杂相互作用
Kaviyarasi Renu
Kaviyarasi Renu
Diabetic cardiomyopathy (DCM), defined as cardiac impairment resulting from the development of diabetes mellitus, has emerged as a global epidemic. DCM primarily denotes myocardial metabolic impairment induced by elevated glucose levels, wi...
Identification of Prognostic Factors for Sepsis or Septic Shock Patients with Cardiac Dysfunction [0.03%]
脓毒症或感染性休克合并心功能不全患者的预后因素分析
Jinsheng Tian,Yan Liu,Yutong Zhao et al.
Jinsheng Tian et al.
Myocardial markers and inflammatory factors have been identified as risk factors for the development of sepsis-induced cardiac dysfunction (SIC), the prognostic significance and clinical utility of utilizing a multi-index combined prognosti...
Acetyl-CoA Short-Chain Synthetase-2 Regulates Myocardial Ischemia/Reperfusion Injury by Targeting Histone Acetylation [0.03%]
乙酰辅酶A短链合成酶-2通过靶向组蛋白乙酰化调节心肌缺血再灌注损伤
Xinhui Chen,Qingling Xu,Wei Ding et al.
Xinhui Chen et al.
Myocardial infarction (MI) remains a leading cause of mortality, and although reperfusion therapy is essential for myocardial salvage, it often results in ischemia-reperfusion (I/R) injury, which contributes substantially to cardiomyocyte n...
Intracoronary Stenting and Restenosis - Randomized Trial of Drug-Eluting Stent Implantation or Drug-Coated Balloon Angioplasty According to Neointima Morphology in Drug-Eluting Stent REstenosis 5: Rationale and Design of the ISAR-DESIRE 5 Trial [0.03%]
冠脉内支架置入与再狭窄：药物洗脱支架植入和药物涂层球囊血管成形术的随机对照试验（ISAR-DESIRE 5）——设计及立题依据
Fiorenzo Simonetti,Felix Voll,Fernando Alfonso et al.
Fiorenzo Simonetti et al.
In-stent restenosis (ISR) is the leading cause of revascularization failure, occurring in up to 10% of patients within 10 years after drug-eluting stent (DES) implantation, and is associated with increased mortality and rehospitalization. G...
Small Interfering RNA (siRNA) for Cardiorenal Disease: Mechanistic Insights from Preclinical and Clinical Studies [0.03%]
小干扰RNA（siRNA）治疗心血管肾脏疾病：来自临床前和临床研究的见解
Sukriti Wadehra,Shareen Singh,Sandeep Kaur et al.
Sukriti Wadehra et al.
Small Interfering RNA (siRNA) is a class of double-stranded, noncoding RNA that silences pathogenic mRNA through the process of RNA interference (RNAi). Its medical application is extensive, particularly in targeting genes associated with c...