Attenuated human bone morphogenetic protein-2-mediated bone regeneration in a rat model of composite bone and muscle injury [0.03%]
人骨形态发生蛋白-2削弱引起的复合骨肌损伤模型中的骨再生受损
Nick J Willett,Mon-Tzu A Li,Brent A Uhrig et al.
Nick J Willett et al.
Extremity injuries involving large bone defects with concomitant severe muscle damage are a significant clinical challenge often requiring multiple treatment procedures and possible amputation. Even if limb salvage is achieved, patients are...
Optimized hyaluronic acid-hydrogel design and culture conditions for preservation of mesenchymal stem cell properties [0.03%]
优化的透明质酸水凝胶设计及培养条件以保持间充质干细胞特性
Faïza Mohand-Kaci,Nabila Assoul,Isabelle Martelly et al.
Faïza Mohand-Kaci et al.
A novel approach that preserved most mesenchymal stem cell (MSC) characteristics was developed using MSC encapsulation in a hydrogel based on hyaluronic acid (HA). An optimized HA-hydrogel composition, whose characteristics were assessed by...
Bioengineering human blood vessel mimics for medical device testing using serum-free conditions and scaffold variations [0.03%]
使用无血清条件和支架变异用于医疗设备测试的工程人体血管模型
Jeremy S Touroo,Jacob R Dale,Stuart K Williams
Jeremy S Touroo
The three-dimensional culture of blood vessel wall cells now permits the construction of a human blood vessel mimic (BVM). Previous studies have used the human BVM as a tool to perform in vitro testing of medical devices and imaging instrum...
A novel murine femoral segmental critical-sized defect model stabilized by plate osteosynthesis for bone tissue engineering purposes [0.03%]
一种新颖的用于骨组织工程的稳定小鼠股骨节段型大缺损模型
Mathieu Manassero,Véronique Viateau,Romano Matthys et al.
Mathieu Manassero et al.
Mouse models are invaluable tools for mechanistic and efficacy studies of the healing process of large bone defects resulting in atrophic nonunions, a severe medical problem and a financial health-care-related burden. Models of atrophic non...
Zero echo time magnetic resonance imaging of contrast-agent-enhanced calcium phosphate bone defect fillers [0.03%]
无回波时间磁共振成像评估磷酸钙骨缺损填充材料的对比剂增强效应
Yi Sun,Manuela Ventura,Egbert Oosterwijk et al.
Yi Sun et al.
Calcium phosphate cements (CPCs) are widely used bone substitutes. However, CPCs have similar radiopacity as natural bone, rendering them difficult to be differentiated in classical X-ray and computed tomography imaging. As conventional mag...
Synthetic peptide-acrylate surface for self-renewal of human retinal progenitor cells [0.03%]
用于人视网膜神经干细胞自我更新的合成肽-丙烯酸酯表面
Petr Baranov,Caio Regatieri,Gustavo Melo et al.
Petr Baranov et al.
Human retinal progenitor cells (hRPCs), isolated from fetal retina, require extracellular matrix proteins such as fibronectin or laminin for successful attachment and self-renewal in vitro. Here we have shown that a novel synthetic vitronec...
Michael T Chung,Jeong S Hyun,David D Lo et al.
Michael T Chung et al.
Background: Although autologous fat grafting has revolutionized the field of soft tissue reconstruction and augmentation, long-term maintenance of fat grafts is unpredictable. Recent studies have reported survival rates o...
The potential of prolonged tissue culture to reduce stress generation and retraction in engineered heart valve tissues [0.03%]
长期组织培养减少工程心脏瓣膜组织应激生成和回缩的潜力
Marijke A A van Vlimmeren,Anita Driessen-Mol,Cees W J Oomens et al.
Marijke A A van Vlimmeren et al.
In tissue-engineered (TE) heart valves, cell-mediated processes cause tissue compaction during culture and leaflet retraction at time of implantation. We have quantified and correlated stress generation, compaction, retraction, and tissue q...
Immortalized functional endothelial progenitor cell lines from umbilical cord blood for vascular tissue engineering [0.03%]
来自脐带血的内皮前体细胞系在血管组织工程中的应用
Praveen K Sobhan,Mahendra Seervi,Jeena Joseph et al.
Praveen K Sobhan et al.
Endothelial progenitor cells (EPCs) play a significant role in multiple biological processes such as vascular homeostasis, regeneration, and tumor angiogenesis. This makes them a promising cell of choice for studying a variety of biological...
Fibrin-based tissue engineering: comparison of different methods of autologous fibrinogen isolation [0.03%]
基于纤维蛋白的组织工程：不同方法的自身纤维蛋白原分离比较
Maren Dietrich,Johanna Heselhaus,Justyna Wozniak et al.
Maren Dietrich et al.
Objective: This study is focussed on the optimal method of autologous fibrinogen isolation with regard to the yield and the use as a scaffold material. This is particularly relevant for pediatric patients with strictly li...
Comparative Study
Tissue engineering. Part C, Methods. 2013 Mar;19(3):216-26. DOI:10.1089/ten.TEC.2011.0473 2013