Mesenchymal stem cells maintain long-term in vitro stemness during explant culture [0.03%]
间充质干细胞在组织块培养中长期维持体内和体外多能性
Anna Otte,Vesna Bucan,Kerstin Reimers et al.
Anna Otte et al.
The advantage of mesenchymal stem cells (MSC) in view of cell and/or tissue replacement after transplantation and their prolonged clinical use raises heavy debates not only in the fields of tissue engineering and regenerative medicine to da...
Efficient generation of functional epithelial and epidermal cells from human pluripotent stem cells under defined conditions [0.03%]
在无饲养层的培养条件下高效地从人多能干细胞中诱导产生功能性的上皮细胞和表皮细胞
Joshua A Selekman,Nicholas J Grundl,Joshua M Kolz et al.
Joshua A Selekman et al.
Human pluripotent stem cells (hPSCs) have an unparalleled potential to generate limitless quantities of any somatic cell type. However, current methods for producing populations of various somatic cell types from hPSCs are generally not sta...
Fabrication of electrospun poly(L-lactide-co-ε-caprolactone)/collagen nanoyarn network as a novel, three-dimensional, macroporous, aligned scaffold for tendon tissue engineering [0.03%]
制备电纺聚乳酸-.Caprolactone/胶原蛋白纳米线网络作为新颖的三维宏观孔对齐支架用于肌腱组织工程
Yuan Xu,Jinglei Wu,Haoming Wang et al.
Yuan Xu et al.
Tissue engineering techniques using novel scaffolding materials offer potential alternatives for managing tendon disorders. An ideal tendon tissue engineered scaffold should mimic the three-dimensional (3D) structure of the natural extracel...
Designing a multicellular organotypic 3D liver model with a detachable, nanoscale polymeric Space of Disse [0.03%]
一种可拆卸的纳米级多细胞器官型三维肝模型及迪斯空间（Space of Disse）的设计
Adam L Larkin,Richard R Rodrigues,T M Murali et al.
Adam L Larkin et al.
The design of in vitro models that mimic the stratified multicellular hepatic microenvironment continues to be challenging. Although several in vitro hepatic cultures have been shown to exhibit liver functions, their physiological relevance...
Validation of Na,K-ATPase pump function of corneal endothelial cells for corneal regenerative medicine [0.03%]
角膜内皮细胞钠钾三磷酸腺苷酶泵功能验证在角膜再生医学中的应用
Shin Hatou,Kazunari Higa,Emi Inagaki et al.
Shin Hatou et al.
Tissue-engineering approaches to cultivate corneal endothelial cells (CECs) or induce CECs from stem cells are under investigation for the treatment of endothelial dysfunction. Before clinical application, a validation method to determine t...
Growing bone tissue-engineered niches with graded osteogenicity: an in vitro method for biomimetic construct assembly [0.03%]
具有分级成骨性的生长骨组织工程生态位的体外组装方法
Serena Danti,Lorenzo Pio Serino,Delfo D&#x;Alessandro et al.
Serena Danti et al.
The traditional bone tissue-engineering approach exploits mesenchymal stem cells (MSCs) to be seeded once only on three-dimensional (3D) scaffolds, hence, differentiated for a certain period of time and resulting in a homogeneous osteoblast...
Comparing autograft, allograft, and tricalcium phosphate ceramic in a goat instrumented posterolateral fusion model [0.03%]
山羊后外侧融合模型中自体移植、异体移植和三钙磷酸盐陶瓷的比较研究
Diyar Delawi,Moyo C Kruyt,Yuan Huipin et al.
Diyar Delawi et al.
The most common application of bone grafts is spinal fusion surgery, in which the use of iliac crest autograft is the gold standard. Harvesting of autograft, however, requires an extra surgical procedure, which is associated with additional...
Comparative Study
Tissue engineering. Part C, Methods. 2013 Nov;19(11):821-8. DOI:10.1089/ten.TEC.2012.0576 2013
In vitro angiogenesis induced by tumor-endothelial cell co-culture in bilayered, collagen I hydrogel bioengineered tumors [0.03%]
双层胶原I型水凝胶生物工程肿瘤中肿瘤内皮细胞共培养诱导的体外血管生成作用研究
Christopher S Szot,Cara F Buchanan,Joseph W Freeman et al.
Christopher S Szot et al.
Although successful remission has been achieved when cancer is diagnosed and treated during its earliest stages of development, a tumor that has established neovascularization poses a significantly greater risk of mortality. The inability t...
Reduction of sample size requirements by bilateral versus unilateral research designs in animal models for cartilage tissue engineering [0.03%]
采用双边与单边研究设计减少动物模型软骨组织工程样本量的要求
Patrick Orth,David Zurakowski,Mauro Alini et al.
Patrick Orth et al.
Advanced tissue engineering approaches for articular cartilage repair in the knee joint rely on translational animal models. In these investigations, cartilage defects may be established either in one joint (unilateral design) or in both jo...
Comparative Study
Tissue engineering. Part C, Methods. 2013 Nov;19(11):885-91. DOI:10.1089/ten.TEC.2012.0699 2013
Effects of humidity and solution viscosity on electrospun fiber morphology [0.03%]
湿度和溶液粘度对电纺纳米纤维形态的影响研究
Roya M Nezarati,Michelle B Eifert,Elizabeth Cosgriff-Hernandez
Roya M Nezarati
Electrospinning is a popular technique to fabricate tissue engineering scaffolds due to the exceptional tunability of fiber morphology that can be used to control scaffold mechanical properties, degradation rate, and cell behavior. Although...