A novel axial-stress bioreactor system combined with a substance exchanger for tissue engineering of 3D constructs [0.03%]
一种新型轴向应力生物反应器系统结合物质交换器用于三维构建组织工程
Song-Tao Li,Yong Liu,Qiang Zhou et al.
Song-Tao Li et al.
This study introduced a prototype of an axial-stress bioreactor system that supports long-term growth and development of engineered tissues. The main features of this bioreactor are an integrated substance exchanger and feedback control of ...
Bone marrow-derived cell concentrates have limited effects on osteochondral reconstructions in the mini pig [0.03%]
骨髓源细胞浓缩物对迷你猪骨软骨复合体修复的有限效果
Michael Jagodzinski,Chaoxu Liu,Daniel Guenther et al.
Michael Jagodzinski et al.
This study investigates the effects of seeding a chondrogenic and osteogenic scaffold with a bone marrow-derived cell concentrate (BMCC) and reports the histological and mechanical properties 3 months after implantation in the miniature pig...
A safe and efficient method to retrieve mesenchymal stem cells from three-dimensional fibrin gels [0.03%]
一种从三维纤黏蛋白凝胶中提取间充质干细胞的安全高效的方法
Bita Carrion,Isaac A Janson,Yen P Kong et al.
Bita Carrion et al.
Mesenchymal stem cells (MSCs) display multipotent characteristics that make them ideal for potential therapeutic applications. MSCs are typically cultured as monolayers on tissue culture plastic, but there is increasing evidence suggesting ...
Three-dimensional characterization of tissue-engineered constructs by contrast-enhanced nanofocus computed tomography [0.03%]
对比增强纳焦点计算机断层扫描技术在组织工程构建体三维表征中的应用研究
Ioannis Papantoniou,Maarten Sonnaert,Liesbet Geris et al.
Ioannis Papantoniou et al.
To successfully implement tissue-engineered (TE) constructs as part of a clinical therapy, it is necessary to develop quality control tools that will ensure accurate and consistent TE construct release specifications. Hence, advanced method...
Pulp cell tracking by radionuclide imaging for dental tissue engineering [0.03%]
应用放射性示踪成像技术追踪 pulp细胞用于牙组织工程
Jean-Baptiste Souron,Anne Petiet,Franck Decup et al.
Jean-Baptiste Souron et al.
Pulp engineering with dental mesenchymal stem cells is a promising therapy for injured teeth. An important point is to determine the fate of implanted cells in the pulp over time and particularly during the early phase following implantatio...
Inhibition of ROCK-myosin II signaling pathway enables culturing of human pluripotent stem cells on microcarriers without extracellular matrix coating [0.03%]
ROCK-肌球蛋白II信号通路的抑制使人类多能干细胞能够在未经细胞外基质包被的小载体上培养
Allen Kuan-Liang Chen,Xiaoli Chen,Yu Ming Lim et al.
Allen Kuan-Liang Chen et al.
Large quantities of human pluripotent stem cells (hPSCs) needed for therapeutic applications can be grown in scalable suspended microcarrier cultures. These microcarriers are coated with animal or human extracellular matrix (ECM) proteins t...
Extracellular matrix domain formation as an indicator of chondrocyte dedifferentiation and hypertrophy [0.03%]
细胞外基质结构域形成作为软骨细胞去分化和肥大的指示指标
Ling Wu,Stephanie Gonzalez,Saumya Shah et al.
Ling Wu et al.
Cartilage injury represents one of the most significant clinical conditions. Implantation of expanded autologous chondrocytes from noninjured compartments of the joint is a typical strategy for repairing cartilage. However, two-dimensional ...
A facile method to fabricate hydrogels with microchannel-like porosity for tissue engineering [0.03%]
一种用于组织工程的类似微通道多孔水凝胶的简易制备方法
Joshua Hammer,Li-Hsin Han,Xinming Tong et al.
Joshua Hammer et al.
Hydrogels are widely used as three-dimensional (3D) tissue engineering scaffolds due to their tissue-like water content, as well as their tunable physical and chemical properties. Hydrogel-based scaffolds are generally associated with nanos...
Three-dimensional microfluidic collagen hydrogels for investigating flow-mediated tumor-endothelial signaling and vascular organization [0.03%]
三维微流控胶原凝胶用于研究流动介导的肿瘤内皮信号传导和血管组织化
Cara F Buchanan,Elizabeth E Voigt,Christopher S Szot et al.
Cara F Buchanan et al.
Hyperpermeable tumor vessels are responsible for elevated interstitial fluid pressure and altered flow patterns within the tumor microenvironment. These aberrant hydrodynamic stresses may enhance tumor development by stimulating the angioge...
The design and development of a high-throughput magneto-mechanostimulation device for cartilage tissue engineering [0.03%]
一种用于软骨组织工程的高通量磁机械刺激装置的设计与开发
Mariea A Brady,Reva Vaze,Harsh D Amin et al.
Mariea A Brady et al.
To recapitulate the in vivo environment and create neo-organoids that replace lost or damaged tissue requires the engineering of devices, which provide appropriate biophysical cues. To date, bioreactors for cartilage tissue engineering have...