Micro-computed tomography-based three-dimensional kinematic analysis during lateral bending for spinal fusion assessment in a rat posterolateral lumbar fusion model [0.03%]
基于微计算机断层摄影的三维运动学分析在侧弯过程中评估脊椎融合的实验研究(大鼠posterolateral腰椎融合模型)
Tomonori Yamaguchi,Nozomu Inoue,Robert L Sah et al.
Tomonori Yamaguchi et al.
Rat posterolateral lumbar fusion (PLF) models have been used to assess the safety and effectiveness of new bone substitutes and osteoinductive growth factors using palpation, radiography, micro-computed tomography (μCT), and histology as s...
Image-based, fiber guiding scaffolds: a platform for regenerating tissue interfaces [0.03%]
基于图像的纤维导向支架:用于再生组织界面的平台
Chan Ho Park,Hector F Rios,Andrei D Taut et al.
Chan Ho Park et al.
In the oral and craniofacial complex, tooth loss is the most commonly acquired disfiguring injury. Among the most formidable challenges of reconstructing tooth-supporting osseous defects in the oral cavity is the regeneration of functional ...
Vivian Lee,Gurtej Singh,John P Trasatti et al.
Vivian Lee et al.
Three-dimensional (3D) bioprinting, a flexible automated on-demand platform for the free-form fabrication of complex living architectures, is a novel approach for the design and engineering of human organs and tissues. Here, we demonstrate ...
Computed tomography-guided tissue engineering of upper airway cartilage [0.03%]
计算机断层扫描引导的上呼吸道软骨组织工程计算体层摄片指导的气道软骨组织工程
Bryan N Brown,Nicholas J Siebenlist,Jonathan Cheetham et al.
Bryan N Brown et al.
Normal laryngeal function has a large impact on quality of life, and dysfunction can be life threatening. In general, airway obstructions arise from a reduction in neuromuscular function or a decrease in mechanical stiffness of the structur...
Rainer Burgkart,Alexandru Tron,Peter Prodinger et al.
Rainer Burgkart et al.
The vascularization of tissue-engineered constructs is yet an unsolved problem. Here, recent work on the decellularization of whole organs has opened new perspectives on tissue engineering. However, existing decellularization protocols last...
Benedikt Weber,Jérôme Robert,Agnieszka Ksiazek et al.
Benedikt Weber et al.
Background: Chronic venous insufficiency (CVI) represents a major global health problem with increasing prevalence and morbidity. CVI is due to an incompetence of the venous valves, which causes venous reflux and distal v...
Control of perfusable microvascular network morphology using a multiculture microfluidic system [0.03%]
利用微流控系统控制可灌注的微血管网络形态
Jordan A Whisler,Michelle B Chen,Roger D Kamm
Jordan A Whisler
The mechanical and biochemical microenvironment influences the morphological characteristics of microvascular networks (MVNs) formed by endothelial cells (ECs) undergoing the process of vasculogenesis. The objective of this study was to qua...
Evaluation of native mesenchymal stem cells from bone marrow and local tissue in an atrophic nonunion model [0.03%]
评估骨髓和局部组织来源的内源性间充质干细胞在萎缩性非联合模型中的效果
Tulyapruek Tawonsawatruk,Michael Kelly,Hamish Simpson
Tulyapruek Tawonsawatruk
Introduction: It has been reported that cells or growth factors might improve bone regeneration in nonunion. However, the intrinsic potential of the nonunion tissue to regenerate bone is still unclear; in particular, it i...
Osteoporotic rat models for evaluation of osseointegration of bone implants [0.03%]
骨质疏松大鼠模型用于评价骨科植入物的骨整合能力
Hamdan S Alghamdi,Jeroen J J P van den Beucken,John A Jansen
Hamdan S Alghamdi
Osseointegration of dental and orthopedic bone implants is the important process that leads to mechanical fixation of implants and warrants implant functionality. In view of increasing numbers of osteoporotic patients, bone implant surface ...
Cell-derived polymer/extracellular matrix composite scaffolds for cartilage regeneration, Part 2: construct devitalization and determination of chondroinductive capacity [0.03%]
细胞衍生聚合物/细胞外基质复合支架用于软骨再生(第二部分):移除细胞成分及评估成软骨诱导能力
Erica J Levorson,Olivia Hu,Paschalia M Mountziaris et al.
Erica J Levorson et al.
This work examined the chondrogenic potential of chondrocyte and mesenchymal stem cell (MSC) coculture generated poly(ɛ-caprolactone) (PCL)/extracellular matrix (ECM) hybrid scaffolds. Five different ratios of chondrocytes and MSCs were co...