Non-Invasive Real-Time Evaluation of Antimicrobial Effects of Biomaterials Through In Vivo Bacterial Tracking [0.03%]
通过活体细菌追踪实时评估生物材料的抗菌效果
Jiahe Li,Liang Zhou,Mingxiao Liu et al.
Jiahe Li et al.
Currently, the evaluation of in vivo antimicrobial efficacy predominantly relies on endpoint detection methods, such as Colony Forming Units (CFU) counting and histopathological staining following animal sacrifice, to assess the antimicrobi...
Improving Human Respiratory Mucosa Tissue Models with Polyamide 6 Scaffolds [0.03%]
具有聚酰胺6支架的改善的人呼吸黏膜组织模型
Niklas Pallmann,Elena Lajtha,Heike Oberwinkler et al.
Niklas Pallmann et al.
Advanced tissue-engineered respiratory models are essential for studying drug or cosmetic toxicity, infection biology and xenobiotic metabolism. Here, we investigated a polyamide 6 (PA6)-based electrospun stromal scaffold as a substitute fo...
Optimizing α-Gal Epitope Removal in Porcine Dermal Matrix: Enzyme Selection and Tissue Form Matter [0.03%]
猪真皮基质中α-半乳糖表位去除的优化：酶的选择和组织形式的影响
Yu-Yue Zhang,Yu-Ting Tang,Sen-Li Huang et al.
Yu-Yue Zhang et al.
Decellularization does not completely remove the matrix-bound α-Gal epitopes in porcine acellular dermal matrix (pADM), and the presence of residual α-Gal epitopes could elicit adverse immunological reactions and cause potential early fai...
Reyhaneh Abolghasemi,Esmat Davoudi-Monfared
Reyhaneh Abolghasemi
Based on various research, different cells are effective for improving the symptoms and paraclinical indicators of patients with chronic spinal cord injury (SCI). A big gap in front of researchers and doctors is to know the source, the numb...
Kareme D Alder,Mason F Carstens,Cole E Bothun et al.
Kareme D Alder et al.
Experimental analyses of knee joint contractures have traditionally utilized a 6-month rabbit model as the gold standard. However, this model is time-intensive and costly. The purpose of this study was to develop an abbreviated rabbit model...
Editorial: The Need for Validation of Organoids in Regenerative Medicine Research [0.03%]
论点：再生医学研究中类器官验证的必要性
John A Jansen
John A Jansen
Natural Killer Cell Membrane Isolation with Minimal Nuclear, Mitochondrial, and Cytosol Contamination [0.03%]
低核DNA、线粒体和细胞质污染的自然杀伤细胞膜分离技术
Vaishali Chugh,Vijaya Krishna K,Vaibhav Patil et al.
Vaishali Chugh et al.
Cell membrane isolation is essential for diverse biological investigations, ranging from fundamental research to advanced therapeutic applications. This study compared two methods-differential centrifugation and discontinuous sucrose densit...
Progress of Pyruvate Kinase M2 in Hepatocellular Carcinoma-Associated Signaling Pathway [0.03%]
乳酸激酶M2在肝细胞癌相关信号通路中的研究进展
Qi Wan,Chunlian Zhao,Rui Zhao
Qi Wan
Hepatocellular carcinoma (HCC) is an aggressive liver tumor with a unique metabolic profile and a shift to glycolytic metabolism. This review discusses the contribution of pyruvate kinase M2 (PKM2) to HCC development and its potential as a ...