Editorial: The Need for Validation of Organoids in Regenerative Medicine Research [0.03%]
论点：再生医学研究中类器官验证的必要性
John A Jansen
John A Jansen
Natural Killer Cell Membrane Isolation with Minimal Nuclear, Mitochondrial, and Cytosol Contamination [0.03%]
低核DNA、线粒体和细胞质污染的自然杀伤细胞膜分离技术
Vaishali Chugh,Vijaya Krishna K,Vaibhav Patil et al.
Vaishali Chugh et al.
Cell membrane isolation is essential for diverse biological investigations, ranging from fundamental research to advanced therapeutic applications. This study compared two methods-differential centrifugation and discontinuous sucrose densit...
Progress of Pyruvate Kinase M2 in Hepatocellular Carcinoma-Associated Signaling Pathway [0.03%]
乳酸激酶M2在肝细胞癌相关信号通路中的研究进展
Qi Wan,Chunlian Zhao,Rui Zhao
Qi Wan
Hepatocellular carcinoma (HCC) is an aggressive liver tumor with a unique metabolic profile and a shift to glycolytic metabolism. This review discusses the contribution of pyruvate kinase M2 (PKM2) to HCC development and its potential as a ...
Mice Models for Peripheral Denervation to Enhance Vascular Regeneration [0.03%]
周围神经节段性切除的小鼠模型在增强血管再生中的应用
Taylor K Brown,Caitlyn Dang,Aurea Del Carmen et al.
Taylor K Brown et al.
Sympathetic innervation plays a critical role in regulating vascular function, yet its influence on vascular regeneration and reinnervation following ischemic injury remains poorly understood. This study develops and validates murine models...
Comparative Insights into Bone Substitutes for Two-Stage Maxillary Sinus Floor Elevation: A Bayesian Network Approach [0.03%]
双阶段上颌窦底提升比较骨替代物的见解：贝叶斯网络方法
Jiayi Chen
Jiayi Chen
To investigate the histomorphometric performance of two-stage maxillary sinus floor elevation (TMSFE) with various bone substitutes in the treatment of atrophic posterior maxilla. Four databases (PubMed, Embase, Web of Science, and The Coch...
Spontaneous Spheroids of hUC-MSCs Regulate Osteogenic Differentiation for Enhancing Osteogenesis [0.03%]
人脐带MSC的自发形成的球体调节成骨分化以增强成骨作用
Xiaotong Wei,Xianqi Li,Zhu Wen et al.
Xiaotong Wei et al.
Stem cells play a critical role in the regeneration process by proliferating and differentiating to form new bone tissue. However, stem cells tend to lose their stemness and pluripotency during in vitro expansion, resulting in reduced bone ...
Research Trends and Hot Topics of Nanozymes in Wound Care: A Bibliometric Analysis [0.03%]
纳米酶在伤口护理中的研究趋势和热点问题的文献计量分析
Shuilan Bao,Yiren Wang,Yuxin Zhong et al.
Shuilan Bao et al.
Nanozymes, as innovative enzyme mimics, hold significant promise for wound care, including antibacterial properties and tissue regeneration. Given their potential to transform wound management, this study utilizes advanced bibliometric tool...
Development of 3D Muscle Cell Culture-Based Screening System for Metabolic Syndrome Drug Research [0.03%]
代谢综合征药物研究的三维肌肉细胞培养基筛查系统的开发
Yoon-Ju Na,Kyoung Jin Choi,Won Hoon Jung et al.
Yoon-Ju Na et al.
Developing effective drug screening methods for type 2 diabetes requires physiologically relevant models. Traditional 2D cell cultures have limitations in replicating in vivo conditions, leading to challenges in assessing drug efficacy. To ...
The Use of HuEpiderm for Evaluating the Effectiveness of Biomaterials in Skin Repair [0.03%]
HuEpiderm在皮肤修复用生物材料有效性评估中的应用研究
Fanshan Qiu,Hang Zeng,Xiaomeng Su et al.
Fanshan Qiu et al.
In vitro experiments, a crucial component of preclinical research, are widely used due to their accessibility and controlled conditions. However, traditional two-dimensional (2D) cell models are limited in their ability to simulate the comp...