Effects of WNT3A and WNT16 on the Osteogenic and Adipogenic Differentiation of Perivascular Stem/Stromal Cells [0.03%]
WNT3A和WNT16对血管周围干细胞成骨及成脂分化的影响
Jia Shen,Xuepeng Chen,Haichao Jia et al.
Jia Shen et al.
Human perivascular stem/stromal cells (hPSC) are a multipotent mesenchymogenic stromal cell population defined by their perivascular locale. Recent studies have demonstrated the high potential for clinical translation of this fluorescence-a...
* Tissue-Specific Extracellular Matrix Enhances Skeletal Muscle Precursor Cell Expansion and Differentiation for Potential Application in Cell Therapy [0.03%]
组织特异性细胞外基质增强骨骼肌前体细胞的增殖和分化以用于细胞治疗
Deying Zhang,Yong Zhang,Yuanyuan Zhang et al.
Deying Zhang et al.
Skeletal muscle precursor cells (MPCs) are considered a key candidate for cell therapy in the treatment of skeletal muscle dysfunction due to injury, disease, or age. However, expansion of a sufficient number of functional skeletal muscle c...
Meniscal Tissue Engineering Using Aligned Collagen Fibrous Scaffolds: Comparison of Different Human Cell Sources [0.03%]
应用有序胶原纤维支架的半月板组织工程：不同人源细胞系的比较研究
Jihye Baek,Sujata Sovani,Wonchul Choi et al.
Jihye Baek et al.
Hydrogel and electrospun scaffold materials support cell attachment and neotissue development and can be tuned to structurally and mechanically resemble native extracellular matrix by altering either electrospun fiber or hydrogel properties...
* Early and Marked Enhancement of New Bone Quality by Alendronate-Loaded Collagen Sponge Combined with Bone Morphogenetic Protein-2 at High Dose: A Long-Term Study in Calvarial Defects in a Rat Model [0.03%]
载有阿仑膦酸的胶原海绵与高剂量骨形态发生蛋白-2早期并显著改善修复块骨中新生骨质量：大鼠颅顶缺损长期实验研究
Tae Hyung Cho,In Sook Kim,Beomseok Lee et al.
Tae Hyung Cho et al.
Choice of appropriate biomaterial is a key factor for the success of recombinant human bone morphogenetic protein (rhBMP)-2 therapy. Inspired by osteogenic cell-differentiating and osteoclast-suppressing capabilities of alendronate (ALN), w...
* Bone Regeneration Mediated by a Bioactive and Biodegradable Extracellular Matrix-Like Hydrogel Based on Elastin-Like Recombinamers [0.03%]
基于弹性蛋白样重组多肽的生物活性和可降解的仿细胞外基质水凝胶介导的骨再生
Dante J Coletta,Arturo Ibáñez-Fonseca,Liliana R Missana et al.
Dante J Coletta et al.
The morbidity of bone fractures and defects is steadily increasing due to changes in the age pyramid. As such, novel biomaterials that are able to promote the healing and regeneration of injured bones are needed to overcome the limitations ...
Exosome-Like Vesicles Derived from Adipose Tissue Provide Biochemical Cues for Adipose Tissue Regeneration [0.03%]
源自脂肪组织的类脂质体为脂肪组织再生提供生化线索
Minjia Dai,Mei Yu,Yan Zhang et al.
Minjia Dai et al.
There is an emerging need for soft tissue replacements in the field of reconstructive surgery for the treatment of congenital deformities, posttraumatic repair, and cancer rehabilitation. Previous studies have shown that the bioactive adipo...
Functional Tissue Engineering: A Prevascularized Cardiac Muscle Construct for Validating Human Mesenchymal Stem Cells Engraftment Potential In Vitro [0.03%]
功能组织工程学：一种预血管化的骨骼肌构造用于验证体内的人骨髓间充质干细胞的植入潜能
Mani T Valarmathi,John W Fuseler,Jay D Potts et al.
Mani T Valarmathi et al.
The influence of somatic stem cells in the stimulation of mammalian cardiac muscle regeneration is still in its early stages, and so far, it has been difficult to determine the efficacy of the procedures that have been employed. The outstan...
Heparin Augmentation Enhances Bioactive Properties of Acellular Extracellular Matrix Scaffold [0.03%]
肝素增强提高无细胞基质支架的活性属性
Daniel S J Park,Holly E M Mewhort,Guoqi Teng et al.
Daniel S J Park et al.
Extracellular matrix (ECM) maintains a reservoir of bioactive growth factors and matricellular proteins that provide bioinductive effects on local cells that influence phenotype and behaviors. Bioactive acellular ECM scaffolds can be used t...
Nadine Lehmann,Torsten Christ,Aila Daugs et al.
Nadine Lehmann et al.
Background: Decellularization of xenogenous cardiovascular structures is a promising approach to create scaffolds for tissue engineering. Unfortunately, handling and pliability of the unfixed tissue is challenging. N-(3-d...
Jenna L Dziki,Luai Huleihel,Michelle E Scarritt et al.
Jenna L Dziki et al.
Suppression of the recipient immune response is a common component of tissue and organ transplantation strategies and has also been used as a method of mitigating the inflammatory and scar tissue response to many biomaterials. It is now rec...