Muscle-Secreted Factors Improve Anterior Cruciate Ligament Graft Healing: An In Vitro and In Vivo Analysis [0.03%]
肌肉分泌因子改善前交叉韧带移植的愈合：体外和体内分析
Corina Adriana Ghebes,Nathalie Groen,Yau Chuk Cheuk et al.
Corina Adriana Ghebes et al.
One of the ligaments most often damaged during sports-the anterior cruciate ligament (ACL)-has poor healing capacity. On damage, reconstructive surgery is performed to restore the mechanical stability of the knee and to reduce the inflammat...
* Efficacy of a Self-Assembling Peptide Hydrogel, SPG-178-Gel, for Bone Regeneration and Three-Dimensional Osteogenic Induction of Dental Pulp Stem Cells [0.03%]
自组装肽水凝胶SPG-178-Gel促进牙髓干细胞三维成骨及骨再生的疗效研究
Jun Tsukamoto,Keiko Naruse,Yusuke Nagai et al.
Jun Tsukamoto et al.
The aim of this study was to assess the efficacy of a self-assembling peptide hydrogel as a scaffold for bone regeneration. We used a neutral and injectable self-assembling peptide hydrogel, SPG-178-Gel. Bone defects (5 mm in diameter) in r...
A Combination of a Polycaprolactone Fumarate Scaffold with Polyethylene Terephthalate Sutures for Intra-Articular Ligament Regeneration [0.03%]
聚己内酯富马酸支架与聚对苯二甲酸乙二醇酯缝线结合的关节内韧带再生方法
Joshua A Parry,Eric R Wagner,Peter L Kok et al.
Joshua A Parry et al.
Intra-articular ligamentous injuries are typically unrepairable and have limited outcomes after graft reconstruction. A combination of porous polycaprolactone fumarate (PCLF) scaffolds with polyethylene terephthalate (PET) sutures was devel...
Michela Bosetti,Alessia Borrone,Massimiliano Leigheb et al.
Michela Bosetti et al.
With the aim to obtain an injectable bioactive scaffold that can accelerate bone formation in sinus lift augmentation, in bony void and fracture repair, we have developed a three-dimensional (3D) jelly collagen containing lysophosphatidic a...
A Tunable, Three-Dimensional In Vitro Culture Model of Growth Plate Cartilage Using Alginate Hydrogel Scaffolds [0.03%]
一种用于生长板软骨的藻酸盐水凝胶支架的可调三维体外培养模型
Alek G Erickson,Taylor D Laughlin,Sarah M Romereim et al.
Alek G Erickson et al.
Defining the final size and geometry of engineered tissues through precise control of the scalar and vector components of tissue growth is a necessary benchmark for regenerative medicine, but it has proved to be a significant challenge for ...
Pivotal Role of Non-cardiomyocytes in Electromechanical and Therapeutic Potential of Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissue [0.03%]
诱导多能干细胞工程心脏组织中非心肌细胞的主导作用及其电机械和治疗潜能
Hiroko Iseoka,Shigeru Miyagawa,Satsuki Fukushima et al.
Hiroko Iseoka et al.
Although engineered cardiac tissues (ECTs) derived from induced pluripotent stem cells (iPSCs) are promising for myocardial regenerative therapy, the appropriate ratio of cardiomyocytes to non-cardiomyocytes is not fully understood. Here, w...
* In Vitro Generated Intervertebral Discs: Toward Engineering Tissue Integration [0.03%]
体外生成的椎间盘：走向工程组织整合方向
Jonathan Iu,Eric Massicotte,Shu-Qiu Li et al.
Jonathan Iu et al.
The intervertebral disc (IVD) is composed of nucleus pulposus (NP) surrounded by multilamellated annulus fibrosus (AF), and is located between the vertebral bodies. Current treatments for chronic neck or low back pain do not completely rest...
Efficacy and Persistence of Allogeneic Adipose-Derived Mesenchymal Stem Cells Combined with Hyaluronic Acid in Osteoarthritis After Intra-articular Injection in a Sheep Model [0.03%]
羊模型膝关节内注射同种异体脂肪来源的间充质干细胞联合透明质酸治疗骨关节炎的有效性和持久性研究
Chenchen Feng,Xuan Luo,Na He et al.
Chenchen Feng et al.
Although a number of studies have reported efficacy of autologous adipose-derived mesenchymal stem cells (AD-MSCs) in treating osteoarthritis (OA) no reliable evidences demonstrate whether allogeneic AD-MSCs can efficiently block OA progres...
Role of Bone Marrow Mononuclear Cell Seeding for Nanofiber Vascular Grafts [0.03%]
骨髓单个核细胞在纳米纤维血管移植物成体中的作用
Takuma Fukunishi,Cameron A Best,Chin Siang Ong et al.
Takuma Fukunishi et al.
Objective: Electrospinning is a promising technology that provides biodegradable nanofiber scaffolds for cardiovascular tissue engineering. However, success with these materials has been limited, and the optimal combinati...
Stromal Cell-Derived Factor-1 Accelerates Cartilage Defect Repairing by Recruiting Bone Marrow Mesenchymal Stem Cells and Promoting Chondrogenic Differentiation<sup/> [0.03%]
干细胞衍生因子-1通过募集骨髓间充质干细胞促进软骨细胞分化以及修复软骨缺陷损伤
Yuze Wang,Xiaojuan Sun,Jia Lv et al.
Yuze Wang et al.
Chemokine stromal cell-derived factor-1 (SDF-1) is a powerful chemoattractant for the localization of CXCR4-positive bone marrow mesenchymal stem cells (BMSCs) into the bone marrow. We studied the effects of SDF-1 on the cartilage defect re...