Influence of External Beam Radiotherapy on the Properties of Polymethyl Methacrylate-Versus Silicone-Induced Membranes in a Bilateral Segmental Bone Defect in Rats [0.03%]
外照射对双侧段骨缺损中PMMA-诱发膜和硅胶-诱发膜的属性的影响研究
Thomas Sagardoy,Camille Ehret,Reine Bareille et al.
Thomas Sagardoy et al.
Introduction: Standard care for malignant tumors arising next to a bone structure is surgical removal with safety margins, followed by external beam radiotherapy (EBRT). Complete tumor removal can result in large bone def...
Kevin Dzobo,Dimakatso Alice Senthebane,Michael Pillay et al.
Kevin Dzobo et al.
Human Beta-Defensin-2 and -3 Mitigate the Negative Effects of Bacterial Contamination on Bone Healing in Rat Calvarial Defect [0.03%]
人β-防御素-2和-3可缓解细菌污染对骨缺损愈合的负面影响：一项大鼠颅顶骨缺损研究
Po-Hui Lee,Meng-Yu Chen,Yu-Lin Lai et al.
Po-Hui Lee et al.
Bacterial contamination during the healing of bone defects frequently compromises the effects of bone regenerative therapy. Human beta-defensin-2 (hBD2) and -3 (hBD3) are antimicrobial peptides of human innate immune system with a broad ant...
Osteogenic Potential of Tauroursodeoxycholic Acid as an Alternative to rhBMP-2 in a Mouse Spinal Fusion Model [0.03%]
以鼠脊柱融合模型评价牛磺胆酸作为rhBMP-2替代物的成骨潜能
Byoung Ju Kim,Yoshie Arai,Eun-Mi Park et al.
Byoung Ju Kim et al.
The non-union rate after lumbar spinal fusion is potentially as high as 48%. To support efficient bone regeneration, recombinant human bone morphogenetic protein-2 (rhBMP-2) is commonly used as it is regarded as the most potent bone-inducin...
Nondestructive/Noninvasive Imaging Evaluation of Cellular Differentiation Progression During In Vitro Mesenchymal Stem Cell-Derived Chondrogenesis [0.03%]
体外间充质干细胞向软骨细胞分化的非破坏性成像评估
Diego Correa,Rodrigo A Somoza,Arnold I Caplan
Diego Correa
Chondrogenic cell differentiation constitutes a multistep program that is spatially and temporally modulated by combinations of bioactive factors that drives the establishment of specific cellular phenotypes. This sequence of events results...
Derivation of Cortical Spheroids from Human Induced Pluripotent Stem Cells in a Suspension Bioreactor [0.03%]
人诱导多能干细胞在悬浮生物反应器中形成皮层类器官球体的分化
Yuanwei Yan,Liqing Song,Jason Madinya et al.
Yuanwei Yan et al.
Human induced pluripotent stem cells (hiPSCs) emerge as a promising source to construct human brain-like tissues, spheroids, or organoids in vitro for disease modeling and drug screening. A suspension bioreactor can be used to generate larg...
* Meltblown Polymer Fabrics as Candidate Scaffolds for Rotator Cuff Tendon Tissue Engineering [0.03%]
静电纺丝聚合物纤维作为肩袖肌腱组织工程候选材料的研究
Thomas L Jenkins,Sean Meehan,Behnam Pourdeyhimi et al.
Thomas L Jenkins et al.
Various biomaterial technologies are promising for tissue engineering, including electrospinning, but commercial scale-up of throughput is difficult. The goal of the study was to evaluate meltblown fabrics as candidate scaffolds for rotator...
* Special Issue on Strategic Directions in Musculoskeletal Tissue Engineering [0.03%]
专题：骨科组织工程的未来方向
Megan L Killian,Anne Gingery
Megan L Killian
* Three-Dimensional Bioprinting of Polycaprolactone Reinforced Gene Activated Bioinks for Bone Tissue Engineering [0.03%]
用于骨组织工程的聚己内酯增强基因激活生物墨水的三维生物打印
Gráinne M Cunniffe,Tomas Gonzalez-Fernandez,Andrew Daly et al.
Gráinne M Cunniffe et al.
Regeneration of complex bone defects remains a significant clinical challenge. Multi-tool biofabrication has permitted the combination of various biomaterials to create multifaceted composites with tailorable mechanical properties and spati...
* Roughness and Hydrophilicity as Osteogenic Biomimetic Surface Properties [0.03%]
粗糙度和亲水性作为生物模拟骨诱导表面属性
Barbara D Boyan,Ethan M Lotz,Zvi Schwartz
Barbara D Boyan
Successful dental and orthopedic implant outcomes are determined by the degree of osseointegration. Over the last 60 years, endosseous implants have evolved to stimulate osteogenesis without the need for exogenous biologics such as bone mor...