Effect of Platelet-Rich Plasma on Chondrogenic Differentiation of Adipose- and Bone Marrow-Derived Mesenchymal Stem Cells [0.03%]
富血小板血浆对脂肪和骨髓来源间充质干细胞软骨分化的效应
Jr-Jiun Liou,Benjamin B Rothrauff,Peter G Alexander et al.
Jr-Jiun Liou et al.
Post-traumatic and focal cartilage defects of the knee affect over 3 million Americans annually. Autologous cell-based cartilage repair, for example, autologous chondrocyte implantation, is limited by the need for ex vivo chondrocyte expans...
An Overview of the Tissue Engineering Market in the United States from 2011 to 2018 [0.03%]
2011-2018年美国组织工程市场概况
Yu Seon Kim,Mollie M Smoak,Anthony J Melchiorri et al.
Yu Seon Kim et al.
This report seeks to provide an update of the current landscape of the tissue engineering market in the United States from an unbiased point of view by analyzing the financial reports provided by tissue engineering companies, as well as dat...
Urinary Bladder Matrix Protects Host in a Murine Model of Bacterial-Induced Lung Infection [0.03%]
尿膀胱基质在细菌诱导的小鼠肺部感染模型中对宿主具有保护作用
Chen Chen,Xiaoping Zhang,Qiao Lin et al.
Chen Chen et al.
Lung infection is a leading cause of human life lost to morbidity and/or mortality. This problem is exacerbated by the alarming emergence of increasingly antibiotic-resistant (AR) microorganisms worldwide and the lack of effective antimicro...
Preformed Vascular Networks Survive and Enhance Vascularization in Critical Sized Cranial Defects [0.03%]
预成型血管网络在颅骨缺损中的存活及促血管化作用
Brianna M Roux,Banu Akar,Wei Zhou et al.
Brianna M Roux et al.
Vascular networks provide nutrients, oxygen, and progenitor cells that are essential for bone function. It has been proposed that a preformed vascular network may enhance the performance of engineered bone. In this study vascular networks w...
An Improved, Chemically Modified RNA Encoding BMP-2 Enhances Osteogenesis In Vitro and In Vivo [0.03%]
改良的化学修饰RNA编码BMP-2可增强体内外成骨效应
Wen Zhang,Rodolfo E De La Vega,Michael J Coenen et al.
Wen Zhang et al.
The use of chemically modified RNA (cmRNA) with increased stability using translation initiator of short untranslated regions (TISU) offers the prospect of finally allowing us to unlock the potent osteogenic properties of BMP-2 in a clinica...
The Role of Continuous Cerebrospinal Fluid Pulsation Stress in the Remodeling of Artificial Vertebral Laminae: A Comparison Experiment [0.03%]
脑脊液连续脉动应力在人工椎板重塑过程中作用的比较实验研究
Linli Li,Yiqun He,Xujun Chen et al.
Linli Li et al.
In this study, we designed a comparison study to investigate the effect of continuous cerebrospinal fluid pulsation (CSFP) stress on the remodeling of artificial vertebral laminae, and we found that the continuous CSFP stress played an impo...
Lattice Microarchitecture for Bone Tissue Engineering from Calcium Phosphate Compared to Titanium [0.03%]
基于磷酸钙与钛的骨组织工程体外试验用微晶格架构的生物相容性及力学性能研究
Tse-Hsiang Chen,Chafik Ghayor,Barbara Siegenthaler et al.
Tse-Hsiang Chen et al.
Additive manufacturing of bone tissue engineering scaffolds will become a key element for personalized bone tissue engineering in the near future. Several additive manufacturing processes are based on extrusion where the deposition of the f...
A Bilayered Poly (Lactic-Co-Glycolic Acid) Scaffold Provides Differential Cues for the Differentiation of Dental Pulp Stem Cells [0.03%]
双层聚乳酸-co-乙交酯支架为牙髓干细胞分化提供不同的线索
Riddhi A Gangolli,Sean M Devlin,Jonathan A Gerstenhaber et al.
Riddhi A Gangolli et al.
In this article we used an FDA-approved biodegradable biomaterial, poly (lactic-co-glycolic acid) (PLGA 75:25) to generate a bilayered scaffold with the capacity to induce differential, layer-specific dentinogenic differentiation of dental ...
Mechanochemical Effects on Extracellular Signal-Regulated Kinase Dynamics in Stem Cell Differentiation [0.03%]
力学作用对干细胞分化过程中ERK动态特性的影响研究
Anirudh Dharmarajan,Michael Floren,Lewis Cox et al.
Anirudh Dharmarajan et al.
Understanding how key signaling molecules are coregulated by biochemical agents and physical stimuli during stem cell differentiation is critical but often lacking. Due to the important role of extracellular signal-regulated kinase (ERK), t...
Human and Rat Bone Marrow-Derived Mesenchymal Stem Cells Differ in Their Response to Fibroblast Growth Factor and Platelet-Derived Growth Factor [0.03%]
人和鼠骨髓来源的间充质干细胞对成纤维细胞生长因子和血小板衍生生长因子的反应不同
Donald Lennon,Luis A Solchaga,Rodrigo A Somoza et al.
Donald Lennon et al.
Tissue engineering requires large numbers of cells with enhanced differentiation properties. Thus, the effect of expansion conditions must be explored. Human and rat marrow-derived mesenchymal stem cells (hMSCs and rMSCs, respectively) were...