Preparation of Immunotolerant Space Under the Skin and Transplantation of Islets in the Space [0.03%]
皮肤下免疫豁免区的制备及胰岛的移植
Rei Kuwabara,Masahide Hamaguchi,Takuya Fukuda et al.
Rei Kuwabara et al.
Although transplantation of islets of Langerhans has been accepted as a fundamental treatment for insulin-dependent diabetes mellitus (IDDM), several problems are still remaining in order that it becomes the standard medical treatment of ID...
Extracellular Matrix Degradation Products Downregulate Neoplastic Esophageal Cell Phenotype [0.03%]
细胞外基质降解产物可下调新生物性食管细胞表型
Lindsey T Saldin,Shil Patel,Li Zhang et al.
Lindsey T Saldin et al.
Extracellular matrix (ECM) biomaterials were used to treat esophageal cancer patients after cancer resection and promoted regrowth of normal mucosa without recurrence of cancer. The present study investigates the mechanisms by which these m...
Injectable Chitosan Hydrogels with Enhanced Mechanical Properties for Nucleus Pulposus Regeneration [0.03%]
一种用于髓核再生的高强度可注射壳聚糖水凝胶研究
Yasaman Alinejad,Atma Adoungotchodo,Michael P Grant et al.
Yasaman Alinejad et al.
A thermosensitive chitosan-based hydrogel was developed, which mimics the mechanical properties of the human nucleus pulposus (NP) tissue and provides a suitable environment for seeded NP cells to live and produce glycosaminoglycans. This s...
Development of Decellularized Cornea by Organic Acid Treatment for Corneal Regeneration [0.03%]
有机酸处理角膜脱细胞技术促进角膜原位再生研究
Hung-Jun Lin,Tsung-Jen Wang,Ting-Wei Li et al.
Hung-Jun Lin et al.
This study successfully developed decellularized corneal scaffolds that were prepared by organic acid, which safely exist in animal tissues and plants. The results showed the highly efficient removal of cell debris from porcine corneas, and...
Optimization of the Platelet-Rich Plasma Concentration for Mesenchymal Stem Cell Applications [0.03%]
优化富含血小板血浆浓度以用于间充质干细胞的研究
Ketao Wang,Zhongli Li,Ji Li et al.
Ketao Wang et al.
In the current study, we screened the effects of different concentrations of platelet-rich plasma (PRP) on the mesenchymal stem cell (MSC) proliferation and differentiation. Our data demonstrated that concentrated PRP exerted different effe...
Effect of Electron Beam Sterilization on Three-Dimensional-Printed Polycaprolactone/Beta-Tricalcium Phosphate Scaffolds for Bone Tissue Engineering [0.03%]
电子束辐照对3D打印聚己内酯/β-磷酸三钙骨组织工程支架的影响
Arnaud Bruyas,Seyedsina Moeinzadeh,Sungwoo Kim et al.
Arnaud Bruyas et al.
Providing customized geometries and improved control in physical and biological properties, 3D-printed polycaprolactone/beta-tricalcium phosphate (PCL/β-TCP) composite constructs are of high interest for bone tissue engineering application...
Construction of Continuous Capillary Networks Stabilized by Pericyte-like Perivascular Cells [0.03%]
类周细胞的管周细胞稳定连续性毛细血管网络的构建
Kyoko Yamamoto,Kohei Tanimura,Masafumi Watanabe et al.
Kyoko Yamamoto et al.
Construction of capillary networks is a fundamental challenge for the development of three-dimensional (3D) tissue engineering. However, it is not well understood how to construct stable capillary networks that maintain a luminal size simil...
The Effects of Metabolic Substrate Availability on Human Adipose-Derived Stem Cell Spheroid Survival [0.03%]
人源脂肪组织来源干细胞球体存活的代谢底物供应的影响
Robert Coyle,Jenny Yao,Dylan Richards et al.
Robert Coyle et al.
Human adipose-derived stem cells (hADSCs) spheroids have displayed remarkable potential for treating ischemic injury. However, low nutrient (i.e., glucose and oxygen) availability in ischemic environments results in limited tissue viability...
Fabricating Muscle-Neuron Constructs with Improved Contractile Force Generation [0.03%]
具有更强收缩力的肌神经结合组织的构建
Md Arifuzzaman,Akira Ito,Kazushi Ikeda et al.
Md Arifuzzaman et al.
In this study, we fabricated innervated skeletal muscle tissue constructs comprising C2C12 myoblasts and PC12 neural cells using a magnetic force-based tissue engineering technique. We found that the C2C12/PC12 co-culture enhanced neural di...
Core-Shell Biphasic Microspheres with Tunable Density of Shell Micropores Providing Tailorable Bone Regeneration [0.03%]
具有可调壳微孔密度的核-壳双相微球用于骨再生修复
Jia Fu,Chen Zhuang,Jiandi Qiu et al.
Jia Fu et al.
We have developed the new core-shell bioceramic CSi-Sr4@CaP-px microspheres with tuning porous shell layer so that the biodegradation of both CSi-Sr4 core and CaP shell is readily adjusted synergistically. This is for the first time, to the...