Effect of Fibroblast Growth Factor-2 and Serum on Canine Mesenchymal Stem Cell Chondrogenesis [0.03%]
表皮生长因子和血清对犬间充质干细胞软骨分化的影响
Kentaro Endo,Naoki Fujita,Takayuki Nakagawa et al.
Kentaro Endo et al.
Tissue engineering using the chondrogenic potential of mesenchymal stem cells (MSCs) is a promising approach for cartilage regenerative therapy. Although dogs are widely used as an animal model for cartilage regeneration, chondrogenic diffe...
Enrichment and Identification of Neural Stem Cells in Neurospheres Using Rigidity-Tunable Gels [0.03%]
利用 rigidity-可调凝胶在神经球中丰富和鉴定神经干细胞
Sweelin Chew,Yukai Zeng,David Khoo et al.
Sweelin Chew et al.
Neural stem cells (NCSs) are integral to establishing in vitro models and regenerative medicine. To this day, there is an unmet need to enrich these cells from a heterogeneous cell population for clinical applications without irreversible m...
Timothy Chen,Gordana Vunjak-Novakovic
Timothy Chen
Reducing ischemia-reperfusion injury would significantly improve patient survival. Current preclinical models are inadequate because they rely on animals, which do not emulate human physiology and the clinical setting. We developed a human ...
Human Testis Extracellular Matrix Enhances Human Spermatogonial Stem Cell Survival In Vitro [0.03%]
人测验干细胞体外存活率增强器
Mark H Murdock,Sherin David,Ilea T Swinehart et al.
Mark H Murdock et al.
This study developed and characterized human testis extracellular matrix (htECM) and porcine testis ECM (ptECM) for testing in human spermatogonial stem cell (hSSC) culture. Results confirmed the hypothesis that ECM from the homologous spec...
Effect of the Bone Morphogenetic Protein-2 Doses on the Osteogenic Potential of Human Multipotent Stromal Cells- Containing Tissue Engineered Constructs [0.03%]
不同浓度骨形态发生蛋白-2对含人多能基质细胞组织工程骨诱导潜能的影响
Adeline Decambron,Nausikaa Devriendt,Nathanael Larochette et al.
Adeline Decambron et al.
A strategy for improving the efficacy of stem cell-based bone tissue engineering (TE) constructs is to combine bone morphogenetic protein-2 (BMP-2) with multipotent stromal cells (MSC). Previous studies on the potential cooperative effect o...
Gingiva-Derived Mesenchymal Stem Cell-Extracellular Vesicles Activate Schwann Cell Repair Phenotype and Promote Nerve Regeneration [0.03%]
牙龈来源的间充质干细胞外泌体激活施万细胞修复表型并促进神经再生
Qin Mao,Phuong D Nguyen,Rabie M Shanti et al.
Qin Mao et al.
Peripheral nerve injuries (PNIs) are common and debilitating, usually resulting in considerable long-term disability and remaining an unmet clinical need. Even though the combination of mesenchymal stem cells (MSCs) and the state-of-the-art...
Generation of Functional Human Adipose Tissue in Mice from Primed Progenitor Cells [0.03%]
在小鼠中，前体细胞生成功能人类脂肪组织
Raziel Rojas-Rodriguez,Jorge Lujan-Hernandez,So Yun Min et al.
Raziel Rojas-Rodriguez et al.
This research describes the use of human mesenchymal progenitor cells for generating functional adipose tissue in vivo in a nude mouse model. Further preclinical development of the methods and insights described in this article can lead to ...
Amnion-Based Scaffold with Enhanced Strength and Biocompatibility for In Vivo Vascular Repair [0.03%]
一种用于体内血管修复的羊膜基血管支架及其制备方法和应用
Megan M Swim,Ambra Albertario,Dominga Iacobazzi et al.
Megan M Swim et al.
This study aimed at developing an amnion-based scaffold suitable for vascular tissue engineering applications and in vivo usage. We successfully produced a multilayered scaffold with improved biomechanical properties and biocompatibility fo...
Production of Tissue-Engineered Small Intestine in Rats with Different Ages of Cell Donors [0.03%]
不同供体年龄细胞构建组织工程小肠的实验研究
Yanchun Liu,Yijie Wang,Jason Chakroff et al.
Yanchun Liu et al.
This study compared side-by-side the impact of donor age on the production of tissue-engineered small intestine (TESI). Each age represents a specific period of life: E18 for fetuses, 5-day-old pups for neonates, 21-day-old rats for weanlin...
Dynamic Culture Substrates That Mimic the Topography of the Epidermal-Dermal Junction [0.03%]
模仿表皮-真皮连接处拓扑结构的动态培养基质
Ayelen L Helling,Priyalakshmi Viswanathan,Katerina S Cheliotis et al.
Ayelen L Helling et al.
In human skin the junction between the epidermis and dermis undulates. Epidermal stem cells pattern according to their position relative to those undulations. Here we describe a rig in which epidermal cells are cultured on a collagen-coated...