Long-Term Cryopreservation and Revival of Tissue-Engineered Skeletal Muscle [0.03%]
长期冷藏及组织工程化骨骼肌的复苏
Lauren Grant,Ritu Raman,Caroline Cvetkovic et al.
Lauren Grant et al.
The ability to freeze, revive, and prolong the lifetime of tissue-engineered skeletal muscle without incurring any loss of function represents a significant advancement in the field of tissue engineering. Cryopreservation enables the effici...
Swine Meniscus: Are Femoral-Tibial Surfaces Properly Tuned to Bear the Forces Exerted on the Tissue? [0.03%]
猪半月板：股骨-胫骨表面承受组织所受力是否合适？
Giuseppe M Peretti,Umberto Polito,Mauro Di Giancamillo et al.
Giuseppe M Peretti et al.
The importance of the present study is linked to how the contact forces act on the knee meniscus in particular, considering the femoral condyles and tibial plateau: this can be useful as a base for the ultimate creation of tissue-engineered...
Poly(Thioketal Urethane) Autograft Extenders in an Intertransverse Process Model of Bone Formation [0.03%]
聚硫酮尿烷自体移植扩展剂的椎间孔骨形成模型试验研究
Madison A P McGough,Stefanie M Shiels,Lauren A Boller et al.
Madison A P McGough et al.
The development of autograft extenders is a significant clinical need in bone tissue engineering. We report new settable poly(thioketal urethane)-based autograft extenders that have bone-like mechanical properties and handling properties co...
Formation of Neoarteries with Optimal Remodeling Using Rapidly Degrading Textile Vascular Grafts [0.03%]
利用可快速降解的纺织血管移植物形成优化重塑的 neoarteries
Takuma Fukunishi,Chin Siang Ong,Cecillia Lui et al.
Takuma Fukunishi et al.
We utilized innovative textile technology to create tissue-engineered vascular grafts (TEVGs) comprised exclusively of rapidly degrading material poly(glycolic acid). Our new technology led to robust neotissue formation in the TEVGs, especi...
Regeneration of Osteochondral Defects Using Developmentally Inspired Cartilaginous Templates [0.03%]
基于软骨模板的软骨骨缺损再生治疗骨折非union或慢性感染骨不连的国际共识和建议
Susan Critchley,Gráinne Cunniffe,Adam O&#x;Reilly et al.
Susan Critchley et al.
Successfully treating osteochondral defects involves regenerating both the damaged articular cartilage and the underlying subchondral bone, in addition to the complex interface that separates these tissues. In this study, we demonstrate tha...
Bone Marrow-Derived Macrophages Enhance Vessel Stability in Modular Engineered Tissues [0.03%]
骨髓来源的巨噬细胞可增强模块化组织工程血管的稳定性
Michael E D West,Elana J B Sefton,Michael V Sefton
Michael E D West
This work demonstrates an effective method of enhancing the stability of a newly formed vasculature in modular engineered tissues in vivo through the counterintuitive implantation of allogeneic macrophages. Furthermore, we provide a detaile...
Peptides and Astroglia Improve the Regenerative Capacity of Alginate Gels in the Injured Spinal Cord [0.03%]
肽和星形胶质细胞增强藻酸盐凝胶在脊髓损伤处的再生能力
Thomas Schackel,Prateek Kumar,Manuel Günther et al.
Thomas Schackel et al.
Axonal bridging across a lesion in the injured spinal cord requires a growth substrate and guidance cues. Using alginate hydrogels with capillary channels we show that poly-l-ornithine and laminin can be stably bound and improve cell adhesi...
Jonathan H Lee,Xiaoman Luo,Xiafei Ren et al.
Jonathan H Lee et al.
Repairing damaged joint cartilage remains a significant challenge. Treatment involving microfracture, tissue grafting, or cell therapy provides some benefit, but seldom regenerates lost articular cartilage. Providing a point-of-care solutio...
Partial Meniscus Replacement with a Collagen-Hyaluronan Infused Three-Dimensional Printed Polymeric Scaffold [0.03%]
一种三维打印聚合物支架的半月板部分置换修复技术：植入支架由胶原透明质酸混合液浸泡而成
Salim A Ghodbane,Andrzej Brzezinski,Jay M Patel et al.
Salim A Ghodbane et al.
The only FDA-approved partial meniscus scaffold, the Collagen Meniscus Implant (CMI), is not approved for reimbursement by government and only reimbursable by certain private insurers. Scaffolds with improved mechanical properties and great...
Hypoxia and TGF-β3 Synergistically Mediate Inner Meniscus-Like Matrix Formation by Fibrochondrocytes [0.03%]
缺氧和TGF-β3协同介导纤维软骨细胞向内侧半月板基质分化的机制研究
Alexander R A Szojka,Brayden D Lyons,Colleen N Moore et al.
Alexander R A Szojka et al.
The interactions of hypoxia and TGF-β3 in aggregates of human meniscus fibrochondrocytes are synergistic in nature, suggesting combinatorial strategies using these factors are promising for tissue engineering the inner meniscus regions. Hy...