Wei Liu,Yilin Cao
Wei Liu
The presented translational research work represents the important progress and evolution of tissue engineering (TE) researches in China from proof-of-concept to actual application of TE technology for health management and biotechnology de...
Comparing Single Cell Versus Pellet Encapsulation of Mesenchymal Stem Cells in Three-Dimensional Hydrogels for Cartilage Regeneration [0.03%]
比较软骨再生三维水凝胶中单细胞与聚集体封装间充质干细胞的效果
Heather Rogan,Francisco Ilagan,Fan Yang
Heather Rogan
While the gold standard for inducing mesenchymal stem cell (MSC) chondrogenesis utilizes pellet culture, most tissue engineering strategies for cartilage regeneration encapsulate MSCs as single cells, partially due to the technical challeng...
Comparative Study
Tissue engineering. Part A. 2019 Oct;25(19-20):1404-1412. DOI:10.1089/ten.TEA.2018.0289 2019
Arnold I Caplan
Arnold I Caplan
This "invited submission" concisely reviews the author's involvement in the early era of tissue engineering and summarizes his perspective. He points out the journal was present in this early era and that it functions as a viewing chamber f...
Preconditioned or IL4-Secreting Mesenchymal Stem Cells Enhanced Osteogenesis at Different Stages [0.03%]
预处理或分泌IL4的间充质干细胞在不同阶段促进骨生成
Tzuhua Lin,Yusuke Kohno,Jhih-Fong Huang et al.
Tzuhua Lin et al.
Pathogen-associated molecular patterns, damage-associated molecular patterns, and other noxious stimuli activate macrophages to induce the proinflammatory responses. Modulation of inflammatory macrophages (M1) into an anti-inflammatory tiss...
Development of Intestinal Scaffolds that Mimic Native Mammalian Intestinal Tissue [0.03%]
模仿原小肠结构的类肠组织工程支架的设计及构建
Mitchell R Ladd,Cait M Costello,Carolyn Gosztyla et al.
Mitchell R Ladd et al.
This study is significant because it demonstrates an attempt to design a scaffold specifically for small intestine using a novel fabrication method, resulting in an architecture that resembles intestinal villi. In addition, we use the versa...
Biochemical Myogenic Differentiation of Adipogenic Stem Cells Is Donor Dependent and Requires Sound Characterization [0.03%]
肌源性分化具有供者依赖性和良好的特征刻画性质的脂肪干细胞的生化分析
Skadi Lau,Melanie Klingenberg,Anna Mrugalla et al.
Skadi Lau et al.
We here showed that even under optimized conditions for biochemical differentiation of adipose-derived stem cells (with respect to a pronounced marker protein expression for a reasonable period of time) it was not possible to obtain functio...
Functional Cortical Axon Tracts Generated from Human Stem Cell-Derived Neurons [0.03%]
由人干细胞衍生神经元组成的具有功能的皮层轴突束
H Isaac Chen,Dennis Jgamadze,James Lim et al.
H Isaac Chen et al.
Axon regeneration is negligible in the adult mammalian brain, and thus, white matter damage often leads to permanent neurological deficits. A novel approach for axon repair is the generation of axon tracts in the laboratory setting followed...
Anne Bernhardt,Emilia Weiser,Sophie Wolf et al.
Anne Bernhardt et al.
Osteocytes play a key role in orchestrating bone homeostasis and turnover and, therefore, in vitro investigations with osteocytes are of high relevance for biomaterial and drug testing in future. In this study, collagen type I gels and coll...
Zhifang Wu,Fu Wang,Zhipeng Fan et al.
Zhifang Wu et al.
The methods developed in this study to manipulate pig tooth germ cells in vitro and in vivo provide a reference for studying whole-tooth regeneration and tooth development in large animals. Of importance, compared with conventional ectopic ...
Hydroxyapatite/Collagen Three-Dimensional Printed Scaffolds and Their Osteogenic Effects on Human Bone Marrow-Derived Mesenchymal Stem Cells [0.03%]
羟基磷灰石/胶原三维打印支架及其对人骨髓间充质干细胞成骨作用的影响
Qing Li,Xiongxin Lei,Xiaofei Wang et al.
Qing Li et al.
Bone loss due to trauma, inflammation, and surgical processes has posed great difficulty in the aesthetic reconstruction of a functional alveolar bone. Tissue engineering and biomaterials, which can promote alveolar bone regeneration, have ...