A Strategy Toward Bridging a Complete Spinal Cord Lesion Using Stretch-Grown Axons [0.03%]
利用拉伸生长的轴突修复完全性脊髓损伤的策略研究
Mindy Ezra Sadik,Ali K Ozturk,Ahmed Albayar et al.
Mindy Ezra Sadik et al.
In this study, we evaluated the ability of stretch-grown tissue-engineered nerve grafts (TENGs) to perform as a living scaffold for axonal regeneration across a severed spinal cord lesion. TENGs, consisting of stretch-grown axons spanning t...
Global Trends of Organoid and Organ-On-a-Chip in the Past Decade: A Bibliometric and Comparative Study [0.03%]
近十年类器官和芯片器官研究的全球趋势：一次 bibliometrix 可视化分析及比较研究
Zhen Wang,Xingdao He,Haowen Qiao et al.
Zhen Wang et al.
Organoid and organ-on-a-chip have evolved as two critical but distinct approaches to develop human physiologically and pathologically relevant in vitro models. Although rapid progress has been witnessed in the past decade, there is no syste...
Polyplexes System to Enhance the LL-37 Antimicrobial Peptide Expression in Human Skin Cells [0.03%]
用于增强LL-37抗菌肽在人类皮肤细胞表达的多聚复合物系统
Maria Isabel Patiño Vargas,Mónica Mesa Cadavid,Claudia Marcela Arenas Gómez et al.
Maria Isabel Patiño Vargas et al.
Inefficient autologous tissue recovery in diverse skin injuries increases the susceptibility of patients to infections caused by multiresistant microorganisms, resulting in a high mortality rate. Nonviral transfection is an attractive alter...
Porcine Small Intestinal Submucosa Mitral Valve Material Responses Support Acute Somatic Growth [0.03%]
猪小肠粘膜下组织二尖瓣材料的反应支持急性躯体生长
Brittany A Gonzalez,Elnaz Pour Issa,Omkar V Mankame et al.
Brittany A Gonzalez et al.
Background: Conceptually, a tissue engineered heart valve would be especially appealing in the pediatric setting since small size and somatic growth constraints would be alleviated. In this study, we utilized porcine small intestinal submuc...
Allogeneic Chondrogenic Mesenchymal Stromal Cells Alter Helper T Cell Subsets in CD4+ Memory T Cells [0.03%]
同种异体软骨基质细胞改变CD4+记忆T细胞中的辅助性T细胞亚群比例
Caoimhe H Kiernan,Patrick S Asmawidjaja,Niamh Fahy et al.
Caoimhe H Kiernan et al.
Implantation of chondrogenically differentiated mesenchymal stromal cells (MSCs) leads to bone formation in vivo through the process of endochondral ossification. The use of allogeneic MSCs for this purpose may be a promising new approach t...
Three-Dimensional Co-culture of Primary Human Osteocytes and Mature Human Osteoclasts in Collagen Gels [0.03%]
人原代骨细胞和成熟破骨细胞的胶原凝胶共培养体系构建及鉴定
Anne Bernhardt,Violetta Österreich,Michael Gelinsky
Anne Bernhardt
Osteoclasts are pivotal cells for bone remodeling and their activity is coordinated by osteocytes that reside inside the bone matrix. In vitro co-cultures of osteocytes and osteoclasts are therefore advantageous to analyze the crosstalk bet...
In Vivo Evaluation of Three-Dimensional Printed, Keratin-Based Hydrogels in a Porcine Thermal Burn Model [0.03%]
基于角蛋白的水凝胶三维打印在猪热烧伤模型中的体内评估
Javier Navarro,Ryan M Clohessy,Robert C Holder et al.
Javier Navarro et al.
Keratin is a natural material that can be derived from the cortex of human hair. Our group had previously presented a method for the printed, sequential production of three-dimensional (3D) keratin scaffolds. Using a riboflavin-sodium persu...
Design and Fabrication of an Automatable, 3D Printed Perfusion Device for Tissue Infusion and Perfusion Engineering [0.03%]
一种用于组织灌注和 perfusion工程的可自动化的、3D 打印的灌注装置的设计与制造
Benjamin K Schilling,Kimberly K Lamberti,Malik J Snowden et al.
Benjamin K Schilling et al.
Tissue decellularization for generating extracellular matrices has become a staple of regenerative medicine in the recent decades, extending from the research setting to clinical usage. Although methods and protocols for tissue decellulariz...
Jenny Robinson,Brendan Harley,Ariella Shikanov
Jenny Robinson
Wharton's Jelly for Augmented Cleft Palate Repair in a Rat Critical-Size Alveolar Bone Defect Model [0.03%]
人胎盘滑膜间充质干细胞修复大鼠上颌骨临界大小缺损的效果研究
Suchit Sahai,Marysuna Wilkerson,Hasen Xue et al.
Suchit Sahai et al.
Secondary alveolar bone grafts (ABGs) are the standard treatment for the alveolar defect in patients with cleft lip and palate (CLP), but remain invasive and have several disadvantages such as delayed timing of alveolar repair, donor-site c...