LINC00687 Regulates PRDX2 Expression in High Glucose-Induced Nonunion after Digital Replantation [0.03%]
高血糖诱导的断指再植不愈合中长链非编码RNA LINC00687对过氧化物酶体丙二醛抗氧化酶2表达的调控作用
Xiangying Wang,Xin He
Xiangying Wang
Diabetic nonunion is a major clinical challenge with unclear molecular mechanisms. This study systematically investigated the key genes and molecular mechanisms of bone nonunion after finger replantation induced by high glucose using Gene E...
Jiahe Li,Liang Zhou,Mingxiao Liu et al.
Jiahe Li et al.
Successful osseointegration is crucial for dental implant stability, yet it remains challenging due to adverse local microenvironments, particularly infection and inflammation. While carbon monoxide (CO) has been recognized as a promising g...
Tissue-Engineered Endothelial Keratoplasty with Controlled Cell Density: Toward Super TEEKs [0.03%]
具有可控细胞密度的组织工程角膜内皮移植向超级TEEKs发展
Inès Aouimeur,Louise Coulomb,Sofiane Fraine et al.
Inès Aouimeur et al.
Over the past 20 years, endothelial keratoplasty procedures have revolutionized the treatment of corneal endothelial disorders. These conditions have now become the leading indication for corneal transplantation in Western countries and acc...
Developing a Functional Osteoarthritis Model Using Human Osteochondral-Synovial Explants [0.03%]
基于人骨软骨-滑膜组织片的膝骨关节炎功能模型构建及其应用研究
Luminita Labusca,Camelia-Mihaela Zara-Danceanu,Anca Emanuela Minuti et al.
Luminita Labusca et al.
Osteochondral explants can serve as valuable ex vivo models for investigating joint development and testing therapeutic interventions in osteoarthritis (OA). The incorporation of synovial tissue in coculture settings more closely reproduces...
Electrically Triggered Fluorescein and Dexamethasone Release from Conducting Polymer Hydrogels [0.03%]
导电聚合物水凝胶中电气触发的荧光素和醋酸倍他米松释放
Matthew S Horrocks,Kirill E Zhurenkov,Matthew S Ting et al.
Matthew S Horrocks et al.
Spatially and temporally controlled drug delivery is an important field to address the limitations of conventional pharmaceutical administration. While many effective controlled drug delivery systems exist, the repertoire of systems that ad...
Sage S Frehner,Matthew Fainor,Galina Dulatov et al.
Sage S Frehner et al.
Cell and tissue engineering therapies provide promise for regenerating damaged intervertebral disc (IVD) tissue and resolving the low back pain that often accompanies it. However, these treatments remain experimental and unavailable for pat...
Chitosan Bioceramic Composites for Bone Regeneration: Insights from In Vitro and In Vivo Studies [0.03%]
基于体外和体内研究的壳聚糖生物陶瓷复合材料的骨再生性能研究
Jeffrey Huang,Jithendra Ratnayake,Maree Gould et al.
Jeffrey Huang et al.
Bone-related pathologies due to injuries, trauma, and disease are a burden on the current health system that will only continue to grow as the population's life expectancy increases. The field of biomaterials aims to address these concerns ...
Engineering Vascularized Transplantable Soft Tissue Free Flaps in Sheep Using the Arteriovenous Loop Technique [0.03%]
采用动脉-静脉环技术制造可供移植的山羊血管化软组织皮瓣
Florian Falkner,Simon Andreas Mayer,Benjamin Thomas et al.
Florian Falkner et al.
The aim of this study was to grow axially vascularized soft tissue flaps in sheep using the arteriovenous loop (AVL) technique to be transplanted for defect reconstruction. This technique may be a promising alternative to conventional free ...
Applications of Tissue-Inducing Biomaterials in Nonosseous Tissues: Evidence Map of Animal Studies [0.03%]
组织诱导性生物材料在非骨组织中的应用：动物研究的证据地图
Yanli Liu,Qiang Wu,Wanlu Zhao et al.
Yanli Liu et al.
Tissue-inducing biomaterials, which promote tissue regeneration without the addition of exogenous cells and/or bioactive factors, have recently attracted increasing interest in the repair of nonosseous tissues. As a key strategy for transfo...
Oxygenation and Temperature Conditioning Alter the Vascular Morphology of Microvascular Constructs [0.03%]
氧合和温度调节改变微血管结构的血管形态
Samuel Nightheart,Adam Rauff,Ethan Dinh et al.
Samuel Nightheart et al.
Revascularization remains a challenge for regenerative medicine strategies. Extensive research has been done to identify key moments of the dynamic wound healing cascade where targeted therapies can elicit a proregenerative response. Howeve...