Tissue Engineering Clinical Council Roundtable Discussion: Opportunities and Challenges in Clinical Translation [0.03%]
组织工程临床咨询圆桌会议讨论：临床转化中的机遇与挑战
J Peter Rubin,Geoffrey C Gurtner,Wei Liu et al.
J Peter Rubin et al.
Sustained Postnatal Skin Regeneration Upon Prenatal Application of Functionalized Collagen Scaffolds [0.03%]
孕期使用功能化胶原支架进行产后持久性皮肤再生
Corien Oostendorp,Paul J Geutjes,Frank Smit et al.
Corien Oostendorp et al.
Primary closure of fetal skin in spina bifida protects the spinal cord and improves clinical outcome, but is also associated with postnatal growth malformations and spinal cord tethering. In this study, we evaluated the postnatal effects of...
Process-Structure-Quality Relationships of Three-Dimensional Printed Poly(Caprolactone)-Hydroxyapatite Scaffolds [0.03%]
聚己内酯/羟基磷灰石多孔支架的三维打印工艺-结构-性能关系研究
Sam Gerdes,Azadeh Mostafavi,Srikanthan Ramesh et al.
Sam Gerdes et al.
Bone defects are common and, in many cases, challenging to treat. Tissue engineering is an interdisciplinary approach with promising potential for treating bone defects. Within tissue engineering, three-dimensional (3D) printing strategies ...
Acellular Biologic Nipple-Areolar Complex Graft: In Vivo Murine and Nonhuman Primate Host Response Evaluation [0.03%]
非细胞生物乳头乳晕复合体移植物的体内小鼠和非人灵长类动物宿主反应评估
Nicholas C Pashos,David M Graham,Brian J Burkett et al.
Nicholas C Pashos et al.
There are more than 3 million breast cancer survivors living in the United States of which a significant number have undergone mastectomy followed by breast and nipple-areolar complex (NAC) reconstruction. Current strategies for NAC reconst...
Acoustic Patterning of Growth Factor for Three-Dimensional Tissue Engineering [0.03%]
声学技术在三维组织工程生长因子图案化中的应用研究
Yaser Shanjani,Sean Michael Siebert,Dai Fei Elmer Ker et al.
Yaser Shanjani et al.
Temporal and spatial presentations of biological cues are critical for tissue engineering. There is a great need in improving the incorporation of bioagent(s) (specifically growth factor(s) [GF(s)]) onto three-dimensional scaffolds. In this...
HepaRG Self-Assembled Spheroids in Alginate Beads Meet the Clinical Needs for Bioartificial Liver [0.03%]
藻酸盐微凝胶内HepaRG自发形成的类器官球体用于生物人工肝的临床需求
Mattia Pasqua,Ulysse Pereira,Antonietta Messina et al.
Mattia Pasqua et al.
In liver tissue engineering, cell culture in spheroids is now well recognized to promote the maintenance of hepatic functions. However, the process leading to spheroids formation is time consuming, costly, and not easy to scale-up for furth...
Type II Photoinitiator and Tuneable Poly(Ethylene Glycol)-Based Materials Library for Visible Light Photolithography [0.03%]
基于聚乙二醇的II型光引发剂和可调材料库用于可见光光刻技术
Xin Yang,Mina Mohseni,Onur Bas et al.
Xin Yang et al.
Stereolithography (SL) has several advantages over traditional biomanufacturing techniques such as fused deposition modeling, including increased speed, accuracy, and efficiency. While SL has been broadly used in tissue engineering for the ...
Application of a Porcine Small Intestine Submucosa Nerve Cap for Prevention of Neuromas and Associated Pain [0.03%]
猪小肠黏膜下组织神经帽的应用及其预防神经瘤和相关疼痛的效果研究
Shahryar Tork,Jennifer Faleris,Anne Engemann et al.
Shahryar Tork et al.
Painful neuroma formation is a common and debilitating sequela of traumatic or oncologic nerve amputations. Studies suggest that isolating transected nerve stumps within protective caps during amputation surgery or revision procedures may a...
Bioprinted Skin Recapitulates Normal Collagen Remodeling in Full-Thickness Wounds [0.03%]
生物打印的皮肤可模拟全层伤口正常的胶原重建造模
Adam M Jorgensen,Mathew Varkey,Anastasiya Gorkun et al.
Adam M Jorgensen et al.
Over 1 million burn injuries are treated annually in the United States, and current tissue engineered skin fails to meet the need for full-thickness replacement. Bioprinting technology has allowed fabrication of full-thickness skin and has ...
Pharmacological Mitigation of Fibrosis in a Porcine Model of Volumetric Muscle Loss Injury [0.03%]
药理学方法缓解体积肌肉损失损伤猪模型中的纤维化现象
Benjamin T Corona,Jessica C Rivera,Kyle A Dalske et al.
Benjamin T Corona et al.
Volumetric muscle loss (VML) resulting from extremity trauma presents functional deficits and fibrosis, ultimately manifesting disability. The extensive fibrotic accumulation is expected to interfere with neural, trophic, vascular, and mech...