A Novel 3D Bioprinting Strategy for Bioengineering of Urethra with Clinical Relevance [0.03%]
一种临床相关的新型3D生物打印策略用于尿道组织工程构建
Teresa Olsen Ekerhult,Mazhar Ortac,Wei Nie et al.
Teresa Olsen Ekerhult et al.
Urethral strictures can cause significant discomfort and progressive urinary tract damage if left untreated. Current reconstructive options, including urethral resection and buccal mucosa grafting, are associated with several limitations su...
Hydrogel-Encapsulated Primed MSCs Enhance Regeneration in Full-Thickness Porcine Burn Wounds [0.03%]
水凝胶包封的预处理间充质干细胞促进猪全层烧伤伤口再生
Kristopher White,Victor Pozzo,Alec R Andrews et al.
Kristopher White et al.
Severe burn injuries pose significant clinical challenges, with high risks of infection, excessive inflammation, and impaired wound healing. Mesenchymal stem cells (MSCs) have shown regenerative and antimicrobial potential; however, their t...
Unidirectional Porous Carbonate Apatite Fabricated by Gelatin-Based Freeze Casting for Bone Regeneration [0.03%]
基于明胶的定向多孔碳酸磷灰石骨修复材料的制备及其性能研究
Zhanrui Lou,Ryo Kishida,Pery Freitas et al.
Zhanrui Lou et al.
To develop bone grafts with superior osteoconductivity, we have fabricated unidirectionally connected porous carbonate apatite (CAp) via gelatin gelation combined with freeze-drying. A composite of calcium carbonate (CaCO3) and gelatin was ...
Regenerative Nanoscaffolds for Chronic Tympanic Membrane Perforation: From Bench to Clinical Translation [0.03%]
用于慢性鼓膜穿孔的再生纳米支架：从实验到临床转化
Woochan Kim,Sang Won Beom,Selin Choi et al.
Woochan Kim et al.
Chronic tympanic membrane (TM) perforation remains difficult to resolve without surgery because of poor intrinsic healing capacity and limitations of passive, nonsurgical materials. Although patch-based approaches are common, most merely pr...
Impact of IFN-γ-Pretreated Umbilical Cord Mesenchymal Stem Cells Implanted in Mesh on Pelvic Organ Prolapse [0.03%]
干扰素-γ预处理的胎盘间充质干细胞植入补片修复盆腔器官脱垂的实验研究
Shiyu Liu,Fei Meng,Yanting Sun et al.
Shiyu Liu et al.
Pelvic organ prolapse (POP) is an urgent clinical challenge, and traditional surgical treatment is limited by high recurrence rate, erosion, mesh exposure, pain, and other complications. Recently, umbilical cord mesenchymal stem cells (UMSC...
The Driving Force of Hierarchical Collagen Fiber Formation: A Review of Tendon, Ligament, and Meniscus Mechanobiology [0.03%]
基于肌腱、韧带和半月板的力学生物学的层级胶原纤维形成的驱动力：综述
Tristan Strayer,Jennifer L Puetzer
Tristan Strayer
In tendons, ligaments, and menisci, collagen fibers running the length of the tissue are the primary source of strength and function. Cells assemble these fibers hierarchically from nanometer-wide fibrils into larger fibers and fascicles, i...
A Nondestructive Raman Spectral Method for Temporal Tracking of Articular Cartilage Maturation [0.03%]
一种用于软骨成熟时间追踪的无损拉曼光谱方法
Nathan J Castro,Greta Babakhanova,Ryan Donahue et al.
Nathan J Castro et al.
Because articular cartilage (AC) lacks inherent repair capacity, research has focused on translating tissue-engineered cartilage to the clinic. Toward this, rapid and nondestructive methods would be useful for determining in-process and rel...
Biosponges Embedded with GDNF Enhance Neuromuscular Recovery Following Volumetric Muscle Loss [0.03%]
嵌有GDNF的生物海绵可增强体积性肌肉损失后的神经肌肉恢复功能
Jamshid Tadiwala,Connor Tobo,Kevin D Sekerak et al.
Jamshid Tadiwala et al.
Volumetric muscle loss (VML) injuries result in an irrecoverable loss of muscle mass and function. VML injury causes loss of both contractile tissue and associated neuromuscular junctions (NMJs). Biosponge (BSG) scaffolds, composed of gelat...
Radiation Modulates the Mechanoresponse of Bone-Homing Triple-Negative Breast Cancer Cells [0.03%]
辐射调节向骨转移的三阴性乳腺癌细胞的力学刺激响应属性
Shreya Venkatesh,Andrea Ordonez,William R Thompson et al.
Shreya Venkatesh et al.
Bone is a common site of breast cancer metastasis, which dramatically increases fracture risk. Recent in vivo bone metastasis studies show that mechanical loading is osteoprotective; however, little is known about how loading regulates brea...