Matrix-Bound Nanovesicles Promote Prohealing Immunomodulation Without Immunosuppression [0.03%]
矩阵结合的纳米囊泡可促进促愈合免疫调节而不会导致免疫抑制
Héctor Capella-Monsonís,Raphael J Crum,William D&#x;Angelo et al.
Héctor Capella-Monsonís et al.
Bioscaffolds composed of extracellular matrix (ECM) have been shown to promote a profound transition in macrophages and T-cells from a proinflammatory to a prohealing phenotype with associated site-appropriate and constructive tissue remode...
Farshid Guilak,Michael Detamore,Gabriela Espinosa et al.
Farshid Guilak et al.
Connor Wright,Serafina Faith Zotter,Wei Shao Tung et al.
Connor Wright et al.
Cartilage injuries are extremely common in the general population, and conventional interventions have failed to produce optimal results. Tissue engineering (TE) technology has been developed to produce neocartilage for use in a variety of ...
A Bioabsorbable Implant Seeded with Adipose-Derived Stem Cells for Adipose Regeneration [0.03%]
负载脂肪来源干细胞的可吸收生物支架用于组织再生修复研究进展
Qiannan Zhao,Shuichi Ogino,Yoshihiro Sowa et al.
Qiannan Zhao et al.
Adipose tissue engineering requires effective strategies for regenerating adipose tissue, with adipose-derived stem cells (ASCs) being favored due to their robust self-renewal capacity and multipotent differentiation potential. In this stud...
Improved Mesenchymal Stem Cell Viability in High-Stiffness, Translational Cartilage Matrix Hydrogels [0.03%]
高强度、转化软骨基质水凝胶中的间充质干细胞存活率较高
Emi A Kiyotake,Claudia Iribagiza,Krisha Pramod et al.
Emi A Kiyotake et al.
Scaffolds made from cartilage extracellular matrix are promising materials for articular cartilage repair, attributed to their intrinsic bioactivity that may promote chondrogenesis. While several cartilage matrix-based scaffolds have suppor...
Interspecies Comparison of Multilayer Mechanical Properties of Synovium Using Atomic Force Microscopy [0.03%]
利用原子力显微镜比较多种生物滑膜的多层力学性质
Shamimur R Akanda,Christopher Walter,Alexandra L Davis et al.
Shamimur R Akanda et al.
The synovium is a loose connective tissue that separates the intra-articular (IA) joint compartments of all diarthrodial joints from the systemic circulation. It can be divided into two layers: the intima, a thin and cell-dense layer atop a...
Primary Human Macrophage and Tenocyte Tendon Healing Phenotypes Changed by Exosomes Per Cell Origin [0.03%]
细胞起源的外泌体改变了主要的人类巨噬细胞和腱细胞的肌腱愈合表型
Devin von Stade,Melinda Meyers,James Johnson et al.
Devin von Stade et al.
The high failure rate of surgical repair for tendinopathies has spurred interest in adjunct therapies, including exosomes (EVs). Mesenchymal stromal cell (MSC)-derived EVs (MSCdEVs) have been of particular interest as they improve several m...
Biodegradable PHBVHHx-PEG/Collagen Hydrogel Scaffolds for Cartilage Repair [0.03%]
用于软骨修复的生物可降解PHBVHHx-PEG/胶原水凝胶支架
Peng Su,Yunan Hu,Jian Li et al.
Peng Su et al.
Recently, there has been increased attention on the treatment of cartilage repair. Overall, we constructed PHBVHHx-COL, a composite hydrogel of PHBVHHx-co-PEG and collagen, and evaluated its cartilage repair efficacy through in vitro and in...
TGFβ-1 and Healing of Bone Defects in Large Animal and Rabbit Models: A Systematic Review [0.03%]
转化生长因子-β1与骨缺损修复的大动物及兔模型系统评价
Sara Trbojevic,Juan M Taboas,Alejandro J Almarza
Sara Trbojevic
Long bone and craniofacial bone fractures amount to an overwhelming expenditure for patients and health care systems each year. Overall, 5-10% of all bone fractures result in some form of delayed or nonunion fractures. Nonunions occur from ...