Comprehensive single-cell analysis reveals cellular heterogeneity and immune interactions in colorectal cancer [0.03%]
Zhenyu Chi,Rui Kong,Song Wang et al.
Zhenyu Chi et al.
Colorectal cancer (CRC) presents considerable therapeutic challenges due to its diverse cellular composition and intricate microenvironment. Our study utilized single-cell RNA sequencing (scRNA-seq) on CRC tissues, examining 18,741 individu...
Wen Fang,Yang Wu,Zhenyu Yang et al.
Wen Fang et al.
Marked interindividual variability in cancer treatment outcomes indicates that traditional strategies focused solely on direct tumor cell eradication are insufficient to explain real world clinical responses. Host responsiveness to therapeu...
Deciphering IFN signaling in gastric cancer: A single-cell and bulk transcriptomic integration reveals CXCR4 as a key immunomodulator and prognostic determinant [0.03%]
Jintian Song,Feihua Wu,Yi Wang et al.
Jintian Song et al.
Background: Gastric cancer (GC), a prevalent solid tumor, features a complex tumor microenvironment (TME) that influences immunotherapy responses. Leveraging single-cell RNA sequencing (scRNA-seq) and bulk transcriptomics...
Inflammatory biomarkers refine progression risk stratification in NSCLC patients with stable disease [0.03%]
Kleinberger M,Laengle S,Berger Jm et al.
Kleinberger M et al.
Introduction: Early risk stratification of non-small cell lung cancer (NSCLC) patients with stable disease (SD) at first restaging is particularly challenging. We explored the prognostic value of clinical and inflammatory...
Single-Cell sequencing investigation of endoplasmic reticulum stress-related genes in gastric cancer prognostic models and identification of NOX5 as a novel therapeutic target [0.03%]
Yue Fan,Feng Liu,Huijun Zuo et al.
Yue Fan et al.
Background: Gastric cancer (GC) has a poor prognosis, and its pathogenesis remains incompletely understood. Endoplasmic reticulum stress (ERS) may influence GC progression, yet ERS-based prognostic models are lacking. We ...
Integrated multi-omics and machine learning highlight PTM-related genes as potential biomarkers in endometrial cancer [0.03%]
Xiaoming Zhou
Xiaoming Zhou
Background: Endometrial cancer, the most common gynecological malignancy, represents about 5 % of all cancers in women, with rising incidence rates. Early-stage patients have favorable outcomes, but advanced or recurrent ...
Inhibition of PTCH1 drug efflux activity enhances chemotherapy efficacy against triple negative breast cancers [0.03%]
Sarah Cogoluegnes,Sandra Kovachka,Thierry Dubois et al.
Sarah Cogoluegnes et al.
Our previous work has revealed that PTCH1, a Hedgehog receptor which is expressed in many aggressive cancers, plays a role in transporting chemotherapeutic drugs out of cancer cells and contributes to their resistance to chemotherapy. PTCH1...
Farrukh Afaq,Satya S Pathi,Balabhadrapatruni V S K Chakravarthi et al.
Farrukh Afaq et al.
Prostate cancer (PCa), a common malignancy, is a leading cause of cancer-related deaths among men. Advances in high-throughput technologies have led to the identification of various genetic alterations, including amplifications, deletions, ...
Corrigendum to "Androgen receptor may promote tumor progression via TTF-1/EGFR pathway in metastatic nasopharyngeal carcinoma" [Translational Oncology, Volume 65, March 2026, 102670] [0.03%]
Chiao-Yun Lin,Chen-Yang Huang,Kar-Wai Lui et al.
Chiao-Yun Lin et al.
Published Erratum
Translational oncology. 2026 May:67:102727. DOI:10.1016/j.tranon.2026.102727 2026
Corrigendum to " Computed tomography- and magnetic resonance imaging-based multi-modality radiomics models for predicting survival in esophageal cancer patients" [Translational Oncology 65 (2026) 102686] [0.03%]
Funing Chu,Dexuan Li,Zhaoqi Wang et al.
Funing Chu et al.
Published Erratum
Translational oncology. 2026 May:67:102702. DOI:10.1016/j.tranon.2026.102702 2026