Helminth-infected Mozambican children with malaria have increased anaemia, cytokines and helminth-specific antibodies [0.03%]
莫桑比克患疟疾的寄生虫感染儿童出现贫血、细胞因子和寄生虫特异性抗体增多的现象
Inocência Cuamba,Rebeca Santano,Berta Grau-Pujol et al.
Inocência Cuamba et al.
Owing to their overlapping geographical distribution and the consequent occurrence of coinfections, several studies have evaluated the impact of helminth infections on malaria immune responses and clinical outcomes. However, little has been...
Cardiotoxin from Naja atra Activates the NLRP3/Caspase-1/GSDMD Pyroptosis Pathway to Induce Skin Tissue Injury [0.03%]
基于NLRP3/caspase-1/GSDMD途径激活的银环蛇心脏毒素致皮肤组织焦亡损伤作用及机制研究
Nianying Qin,Yiling Zhai,Hongying Cao et al.
Nianying Qin et al.
Background: Cardiotoxin (CTX) from Naja atra venom is a principal virulence factor responsible for progressive local tissue necrosis and systemic inflammation following snakebite. Despite its clinical importance, the mole...
Novel binding partners of the Vacuolar Transporter Chaperone (VTC) complex in Acidocalcisomes of Leishmania tarentolae [0.03%]
利什曼原疟虫酸钙体中的Vacuolar Transporter Chaperone (VTC)复合物的新结合蛋白
Paulina Królak,Orquidea Ribeiro,Bernadette Gehl-Väisänen et al.
Paulina Królak et al.
Acidocalcisomes are evolutionarily conserved acidic organelles that are rich in cations and inorganic phosphate, primarily polyphosphates. In kinetoplastid parasites, acidocalcisomes and their polyphosphate content are essential for osmoreg...
Fidelity of the implementation of antirabies vaccination for dogs and cats in the Plurinational State of Bolivia [0.03%]
玻利维亚犬猫狂犬病疫苗实施的准确性
Andrés Rodrigo Gómez-Vidal,Héctor Vélez Santamaría,Nathalia M Correa-Valencia et al.
Andrés Rodrigo Gómez-Vidal et al.
The rabies virus is a serious global public health threat that primarily affects vulnerable populations in rural areas. Despite vaccination efforts, some countries, such as the Plurinational State of Bolivia, continue to report human fatali...
Observational Study
PLoS neglected tropical diseases. 2026 Jul 10;20(7):e0014535. DOI:10.1371/journal.pntd.0014535 2026
Infection of Rhesus Macaques with O'nyong-nyong virus UVRI-0804 recapitulates key aspects of human clinical disease [0.03%]
O'nyong-nyong病毒UVRI-0804感染食蟹猴可重现人类临床症状的关键方面
Hannah K Jaeger,Michael Denton,Takeshi F Andoh et al.
Hannah K Jaeger et al.
O'nyong-nyong virus (ONNV) is a mosquito-borne alphavirus first isolated in Uganda in 1959. Since its discovery, ONNV has caused several outbreaks in Africa, manifesting clinically as fever, rash, and joint/muscle pain lasting months. Curre...
Anthrax outbreak associated with the consumption and handling of carcasses of livestock that suddenly died, Kanungu District, Uganda, June-November 2024 [0.03%]
2024年6月至11月乌干达卡努恩古地区与食用和处理突然死亡的牲畜尸体相关的炭疽疫情
Charity Mutesi,Richard Migisha,Hannington Katumba et al.
Charity Mutesi et al.
Background: Anthrax is a recurrent zoonosis in Uganda, with 11 outbreaks reported in 2024. On September 17, 2024, the Ministry of Health received reports of two human deaths in Kanungu District, later confirmed as anthrax...
The convergence of health system, climate, and social pathways in Malawi's 2022-2024 cholera outbreak - A qualitative assessment [0.03%]
马拉维2022至2024年霍乱疫情中卫生系统、气候与社会途径的汇聚——定性评估
Shahar Livne,Matamando Mwendera,Stellar Chibvunde et al.
Shahar Livne et al.
Climate-related disasters increase cholera risks, yet their contribution to outbreaks is often explained through microbiological, epidemiological or ecological lenses, limiting our understanding of system convergence. Examining the 2022-202...
Time trends in the burden of scabies from 1990 to 2021, and projections to 2050: Insights based on the Global Burden of Disease Study 2021 [0.03%]
基于全球疾病负担研究（2021年）的1990至2021年的疥疮疾病负担变化及2050年预测趋势分析
Fangqin Peng,Wenjie Hao,Yating Peng
Fangqin Peng
Background: Scabies is a parasitic skin disease known since ancient times, yet it remains a persistent and significant global health challenge in the modern era affecting populations around the world. This study aims to a...
Co-circulation of Trypanosoma cruzi and Leishmania spp. in Northwestern Colombia, a major migratory corridor [0.03%]
哥伦比亚西北部查格RES病毒流行的驱动因素及其对美洲锥虫病和利什曼病传播的影响
Omar Cantillo-Barraza,Adriana Pabón,Hugo O Valdivia et al.
Omar Cantillo-Barraza et al.
Trypanosoma cruzi and Leishmania spp. are the causative agents of Chagas disease and Leishmaniasis, respectively. These flagellates have complex transmission cycles involving a variety of mammal hosts, some of which may serve as potential r...
Socioeconomic and ecological drivers of contagious pig diseases in free-range systems: Evidence from Gwembe Valley, Zambia [0.03%]
赞比亚格韦姆贝谷地放养猪的传染病流行的社会经济和生态驱动因素：证据来自格韦姆贝山谷，赞比亚
Catherine Besnart Dzombe,Herman Chambaro,Karl Rich et al.
Catherine Besnart Dzombe et al.
Free-range pig systems support rural livelihoods in Zambia but increase exposure to contagious diseases through unrestricted movement, environmental contamination, and informal trade. We explored non-biological drivers of disease risk in Gw...