Time-specific bidirectional links between the maternal microbiome, milk composition, and infant gut microbiota [0.03%]
母体微生物组、乳汁组成和婴儿肠道微生物组的时间特异性双向联系
Lishi Deng,Kelsey Fehr,Laeticia Celine Toe et al.
Lishi Deng et al.
Early-life gut microbiome development is shaped by complex maternal and nutritional influences, yet the temporal and directional structure of these interactions remains unclear. In a longitudinal study of 152 mother-infant dyads in rural Bu...
Transitions in lung microbiota landscape associate with distinct patterns of pneumonia progression [0.03%]
肺微生物群的转变与不同类型的肺炎进展模式有关
Jack T Sumner,Stefanie Huttelmaier,Chiagozie I Pickens et al.
Jack T Sumner et al.
The precise microbial determinants driving clinical outcomes in severe pneumonia are unknown. Competing ecological forces produce dynamic microbiota states in health and disease, and a more thorough understanding of these states has the pot...
Richard A Insel,John B Jarman,Pedro J Torres et al.
Richard A Insel et al.
An early-life microbiota with increased Bifidobacterium and human milk oligosaccharide (HMO) utilization genes has been linked to decreased risk of childhood allergic disease. As infant microbiomes increasingly have reduced Bifidobacterium,...
Anne E D&#x;Armond,Jay K Kolls
Anne E D&#x;Armond
In this issue of Cell Host & Microbe, Sumner et al. utilize a multi-omics approach to delineate various "pneumotypes," or distinct microbial states, in the lungs of patients with pneumonia. These pneumotypes have potential predictive value ...
Hide and seek: Cryptococcus evasion of microglial sensing enables meningitis [0.03%]
藏与追：新隐球菌躲避小胶质细胞的感应能力致脑膜炎
Jessica C Hargarten,Amariliz Rivera
Jessica C Hargarten
In this issue of Cell Host & Microbe, Reyes et al.1 uncovered that delayed microglial activation provides Cryptococcus a temporal advantage in establishing central nervous system infections in a CD4+ T cell-competent setting. This delay car...
Daniela Ramírez-Sánchez,Detlef Weigel
Daniela Ramírez-Sánchez
In this issue of Cell Host & Microbe, Xu and colleagues investigate host pH modulation as a microbiome-mediated defense mechanism. Pseudomonas strains can protect wheat against the pathogenic fungus Fusarium graminearum by counteracting alk...
Chrishan M Fernando,Nicole D Marino
Chrishan M Fernando
Across all domains of life, immune systems rely on nucleotide-based signaling molecules to activate defense responses. In a recent Cell Host & Microbe study, Doherty, Nomburg, and colleagues identify and characterize diverse families of vir...
Maren Ziegler,Claudia Pogoreutz
Maren Ziegler
Microbial symbioses enable animals to colonize the most extreme habitats on Earth. The study by Wei et al.1 in this issue of Cell Host & Microbe elucidates how intricate molecular adaptations of a coral host and its newly discovered microbi...
Frances Pitsillides,Hassan Salem
Frances Pitsillides
In a recent publication in Science, Nishino et al.1 reveal the evolutionary co-option of an auditory structure into a newly identified type of symbiotic organ. This organ, found on the hindlegs of female stinkbugs, houses fungi that act as ...
A commensal bacterium secretes effector proteins to establish population heterogeneity in the gut [0.03%]
一种共生细菌分泌效应蛋白以在肠道中建立种群异质性
Anna P Zagieboylo,Ran Mo,Bentley Lim et al.
Anna P Zagieboylo et al.
The gut microbiome, comprising hundreds of individual species, is a complex and dynamic host-associated microbial community. However, how microbes interact within populations of the same species is largely unexplored. Using single-cell appr...