The genetic repertoire of deep-sea microbiome: From sequence to structure and function [0.03%]
深海微生物组的遗传组成：从序列到结构和功能
Yang Guo,Zongan Wang,Denghui Li et al.
Yang Guo et al.
The deep sea, as the largest and maybe most hostile environment on Earth, is still underexplored, especially regarding its genetic repertoire. Yet, previous work has revealed significant habitat-specific deep-sea biodiversity. Here, we pres...
Variations in the latitudinal diversity gradients of the ocean microbiome [0.03%]
海洋微生物群的纬度多样性变化规律差异
Dominic Eriksson,Jonas Schiller,Alexandre Schickele et al.
Dominic Eriksson et al.
Latitudinal diversity gradients (LDGs), which typically decline from the equator to the poles, are a pervasive macroecological pattern. However, their generality and drivers in the ocean microbiome remain widely unresolved. We integrated gl...
William J Massey,J Mark Brown
William J Massey
There is now overwhelming evidence that glucagon-like peptide 1 (GLP-1) receptor agonists have many health benefits. In this issue of Cell Host & Microbe, Bian et al. find that the gut microbiome is implicated in the psychological effects o...
Kelvin G K Goh,Glen C Ulett
Kelvin G K Goh
In this issue of Cell Host & Microbe, Cohen and colleagues evaluate bacterial-fungal co-infection of the female reproductive tract. They demonstrate that cross-kingdom co-infections can lead to intricate polymicrobial interactions, enhanced...
Katsumi Maenaka,Shunsuke Kita,Hideo Fukuhara
Katsumi Maenaka
The measles vaccine provides lifelong protection despite high virus mutation rates. In this issue of Cell Host & Microbe, Acciani et al. demonstrate that vaccine-induced antibodies target highly conserved epitopes within the viral glycoprot...
Guangqing Lu,Jun R Huh
Guangqing Lu
Maternal helminth exposure may confer offspring protection against respiratory viruses, but the immune pathways and mediators are not well known. In this issue, Fernandes et al. demonstrate that helminth-induced remodeling of maternal micro...
NAD to the bone: How bacteria put phages under aRES-t … and how phages fight back [0.03%]
深入骨髓的NDM：细菌如何使噬菌体ARS止步……以及噬菌体如何反击
Danny P Williams-Jones,Jack P K Bravo
Danny P Williams-Jones
In this issue of Cell Host & Microbe, Osterman et al. discover aRES,1 a new family of bacterial immune proteins that deplete cellular NAD+, generating cleavage products that cannot be utilized by canonical phage NAD+ regeneration pathways. ...
Cynthia L Hsu
Cynthia L Hsu
Hepatic encephalopathy is a devastating neuroinflammatory complication of cirrhosis driven by systemic metabolic dysregulation across the gut-liver-brain axis. In a recent article in Cell, Aggarwal et al. engineered a multi-strain bacterial...
Microbiota-driven gut-brain signaling underlies antidepressant effects of a GLP-1 analog [0.03%]
肠道菌群驱动的肠脑信号传导决定了GLP-1类似物的抗抑郁效果
Liang Bian,Yang Cai,Yuan Zhang et al.
Liang Bian et al.
Despite widespread clinical use of glucagon-like peptide-1 receptor (GLP-1R) agonists for metabolic disease, their neuropsychiatric effects remain poorly understood and controversial. Here, we demonstrate that liraglutide alleviates depress...
Microbiota-derived short-chain fatty acids mediate Candida albicans gastrointestinal colonization resistance [0.03%]
短链脂肪酸介导肠道微生物群对白色念珠菌定植的抵抗作用
Animesh A Mishra,Suzette N Palmer,Christina M Zarek et al.
Animesh A Mishra et al.
The gut microbiota plays critical roles in constraining Candida albicans colonization of the gastrointestinal (GI) tract, which is a key precursor to disseminated fungal infection in immunocompromised hosts. Depletion of commensal microbiot...