Colin D Sempeck,Matthew R Olm
Colin D Sempeck
Many microbiome analysis techniques can only detect the microbes present in the reference genome database used. In this issue of Cell Host & Microbe, Cha et al. establish an improved genome database of the human oral microbiome, which they ...
A duet of T6SS effectors [0.03%]
T6SS效应蛋白双人舞
Lingfang Zhu,Xihui Shen
Lingfang Zhu
How do gut bacteria outcompete rivals in dense microbial ecosystems? In this issue of Cell Host & Microbe, Li et al.1 report a Bacteroides T6SS adaptor protein C-orchestrated co-secretion mechanism of T6SS effectors Bacteroides T6SS phospha...
Lei Song,Zhao-Qing Luo
Lei Song
Bacterial pathogens interfere with host cell signaling by inducing post-translational modifications. In this issue, Xu and colleagues report that the Shigella flexneri effector OspB catalyzes an unusual recombination reaction between pro-de...
Xinyi Gu,Bing Zhai
Xinyi Gu
Due to the presence of gut microbiota, enteric pathogens such as Salmonella are rarely alone in their battleground with the host. In a recent study published in Nature, Jaswal et al. revealed that Candida albicans, a fungus frequently found...
Biao Wan,Muammar Mansor
Biao Wan
Discovering new microbial metabolism is every microbiologist's dream. Microorganisms that respire iron coupled to sulfide oxidation were considered a myth, incapable of competing against fast abiotic reactions. Recently, in Nature, Chen et ...
The impact of COVID-19 on children and lessons for pandemic preparedness [0.03%]
新冠肺炎疫情对儿童的影响及启示：完善大流行病防范机制
Shaun K Morris,Karina A Top
Shaun K Morris
Children and adults experienced the COVID-19 pandemic differently. While the impact on children was significant, it was different from what had originally been expected. Here, we outline key developments and learnings from the COVID-19 pand...
The Africa COVID-19 legacy-Improved vaccinology for pandemic preparedness [0.03%]
非洲新冠肺炎疫情的遗产——提高大流行病准备状态下的疫苗学研究水平
Penny L Moore,Shabir A Madhi,Glenda Gray
Penny L Moore
The COVID-19 pandemic caused global disruption that reverberated across Africa and revealed deep systemic vulnerabilities. Nonetheless, the scientific response to SARS-CoV-2 catalyzed unprecedented global scientific collaboration, establish...
Thiago Cerqueira-Silva,Manoel Barral-Netto,Viviane Sampaio Boaventura
Thiago Cerqueira-Silva
Despite proven effectiveness, vaccine uptake in high-risk groups remains low due to access barriers, misinformation, and limited trial data. In this Forum, we discuss how targeted communication, optimized vaccine formulations, inclusive tri...
Systems virology as a cornerstone for pandemic responsiveness: A G2P-Japan perspective [0.03%]
系统病毒学作为大流行应对的基石：G2P-Japan的视角
Kei Sato
Kei Sato
Pandemic preparedness is critical as we face potential threats of infectious diseases. Systems virology and collaborative/responsive science are key infrastructures that facilitated scientific advances during the SARS-CoV-2 pandemic. As dis...
Bette Korber,Will Fischer,James Theiler
Bette Korber
The global response to COVID-19 during the pandemic resulted in an unprecedented view of viral evolution. Here, we discuss both the capacity of the scientific community to monitor viral evolution on a global scale in real time and the mutat...