Mitochondrial dysfunction generates a growth-restraining signal linked to pyruvate in Drosophila larvae [0.03%]
线粒体功能紊乱通过与乳酸相互作用的方式在果蝇幼虫生长限制信号中产生了一种增长抑制信号
Jack George,Tea Tuomela,Esko Kemppainen et al.
Jack George et al.
The Drosophila bang-sensitive mutant tko25t, manifesting a global deficiency in oxidative phosphorylation due to a mitochondrial protein synthesis defect, exhibits a pronounced delay in larval development. We previously identified a number ...
Expansion of a fly TBI model to four levels of injury severity reveals synergistic effects of repetitive injury for moderate injury conditions [0.03%]
扩展果蝇TBI模型以涵盖四个不同的损伤严重程度并揭示中度损伤条件下重复损伤的协同效应
Lauren J Putnam,Ashley M Willes,Brooke E Kalata et al.
Lauren J Putnam et al.
Several million traumatic brain injury (TBI) events are reported in the United States annually. However, mild TBI events often go unreported, and mild and repetitive mild TBI conditions are challenging to model. Fruit flies (Drosophila mela...
A standardized nomenclature and atlas of the male terminalia of Drosophila melanogaster [0.03%]
果蝇(Drosophila melanogaster)雄性外生殖器的命名法和图谱标准
Gavin Rice,Jean R David,Yoshitaka Kamimura et al.
Gavin Rice et al.
Animal terminalia represent some of the most diverse and rapidly evolving structures in the animal kingdom, and for this reason have been a mainstay in the taxonomic description of species. The terminalia of Drosophila melanogaster, with it...
Bivalency in Drosophila embryos is associated with strong inducibility of Polycomb target genes [0.03%]
双向性与果蝇胚胎中Polycomb靶基因的强诱导性有关
Arslan Akmammedov,Marco Geigges,Renato Paro
Arslan Akmammedov
Polycomb group (PcG) and Trithorax group (TrxG) proteins orchestrate development of a multicellular organism by faithfully maintaining cell fate decisions made early in embryogenesis. An important chromatin mark connected to PcG/TrxG regula...
A modular toolset of phiC31-based fluorescent protein tagging vectors for Drosophila [0.03%]
一系列基于phiC31的荧光蛋白标记载体在果蝇中的应用
Jun Luo,Pingping Shen,Jiong Chen
Jun Luo
The Drosophila transgenic technology and fluorescent protein fusions are powerful tools to analyze protein expression patterns, subcellular localization and protein dynamics. Recently, the Drosophila transgenic technology has been improved ...
Christopher M Groen,Jewel L Podratz,Kevin Treb et al.
Christopher M Groen et al.
Drosophila melanogaster has recently been developed as a simple, in vivo, genetic model of chemotherapy-induced peripheral neuropathy. Flies treated with the chemotherapy agent cisplatin display both a neurodegenerative phenotype and cell d...
Maintenance of Rhodopsin levels in Drosophila photoreceptor and phototransduction requires Protein Kinase D [0.03%]
果蝇视杆细胞中视紫红质的维持需要蛋白激酶D
Sudipta Ashe,Shweta Yadav
Sudipta Ashe
During Drosophila phototransduction, the G protein coupled receptor (GPCR) Rhodopsin (Rh1) transduces photon absorption into electrical signal via G-protein coupled activation of phospholipase C (PLC). Rh1 levels in the plasma membrane are ...
A model-based high throughput method for fecundity estimation in fruit fly studies [0.03%]
基于模型的果蝇繁殖力估计的高通量方法
Enoch Ng&#x;oma,Elizabeth G King,Kevin M Middleton
Enoch Ng&#x;oma
The ability to quantify fecundity is critically important to a wide range of experimental applications, particularly in widely-used model organisms such as Drosophila melanogaster. However, the standard method of manually counting eggs is t...
Functional interplay between ribosomal protein paralogues in the eRpL22 family in Drosophila melanogaster [0.03%]
拟南芥中rpl22家族同源异形体的功能互作
Catherine M Mageeney,Michael G Kearse,Brett W Gershman et al.
Catherine M Mageeney et al.
Duplicated ribosomal protein (RP) genes in the Drosophila melanogaster eRpL22 family encode structurally-divergent and differentially-expressed rRNA-binding RPs. eRpL22 is expressed ubiquitously and eRpL22-like expression is tissue-restrict...
Localization and translation control of slam in Drosophila cellularization [0.03%]
果蝇细胞形成期SLAM的局部化和翻译调控
Shuling Yan,Jörg Großhans
Shuling Yan
In this extra view, we comment on our recent work concerning the mRNA localization of the gene slow as molasses (slam). slam is a gene essential for the polarized invagination of the plasma membrane and separation of basal and lateral corti...