Cuiyun Geng,Paul M Macdonald
Cuiyun Geng
Axial patterning in Drosophila relies on the deployment of patterning proteins at specific regions within the developing oocyte. This process involves transport of mRNAs from the nurse cells to the oocyte, localization of mRNAs within the o...
Mary Ann Price
Mary Ann Price
Many exciting new discoveries in the fields of cell biology and development were presented at JDRC8, including the molecular characterization of long-studied phenomena such as cell competition, the discovery of long-sought-after molecules s...
The Genetics Society of Canada takes a flight with Drosophila to celebrate its 50th year [0.03%]
加拿大遗传学会高举果蝇大旗庆祝五十周年大庆
Paul Lasko
Paul Lasko
The Genetics Society of Canada (GSC) held its 50th Anniversary Celebration June 18-21, 2007 in the New Residence Hall of McGill University in Montreal in conjunction with the 9(th) Canadian Drosophila Research Conference (CanFly), which is ...
Design and utility of temperature-sensitive Gal4 mutants for conditional gene expression in Drosophila [0.03%]
条件性基因表达的温度敏感型Gal4突变体的设计、制备及其应用价值探讨——以果蝇为例
Kajari Mondal,K VijayRaghavan,Raghavan Varadarajan
Kajari Mondal
Temperature-sensitive (ts) mutants are valuable tools to study the function of essential genes in vivo. Despite their widespread use, little is known about mechanisms responsible for the temperature-sensitive (ts) phenotype, or of the trans...
Sunil Archak,Javaregowda Nagaraju
Sunil Archak
Microsatellites show tremendous variation between genomes in terms of their occurrence and composition. Availability of whole genome sequences allows us to study microsatellite characteristics of fully sequenced insect genomes to understand...
Yun Zhao,Chao Tong,Jin Jiang
Yun Zhao
Cell signaling mediated by the Hedgehog (Hh) family of secreted proteins is essential for metazoan development and its malfunction causes congenital disorders and cancer. The seven-transmembrane protein Smoothened (Smo) transduces the Hh si...
On the roles of the Drosophila KASH domain proteins Msp-300 and Klarsicht [0.03%]
果蝇KASH域蛋白Msp-300和Klarsicht的作用机制研究进展
Xuanhua Xie,Janice A Fischer
Xuanhua Xie
KASH (Klarsicht, Anc-1, Syne-1 homology) domain-containing proteins anchor the nucleus to the actin cytoskeleton or to microtubules. KASH proteins thus play pivotal roles in a variety of developmental processes where nuclear positioning is ...
Azaria Kam Yan Wong,Ho Yin Edwin Chan,Wing Man Chan
Azaria Kam Yan Wong
Pei-Yu Wang,Wei-Ling Chang,Li-Mei Pai
Pei-Yu Wang
Morphogen gradients provide unique positional information within a tissue. Cells that are sensitive to the concentration of the morphogen integrate this signal and develop an appropriately distinct cell fate. A morphogen gradient is usually...
Nicholas S Tolwinski
Nicholas S Tolwinski
The 49(th) Annual Drosophila Research Conference was held in the sunny confines of San Diego. As usual, large numbers of Drosophila scientists working in fields as different as immunology and evolution descended on the venue. The meeting sh...