Tomoko Yamakawa,Elzava Yuslimatin Mujizah,Kenji Matsuno
Tomoko Yamakawa
The development of all animal embryos is initially directed by the gene products supplied by their mothers. With the progression of embryogenesis, the embryo's genome is activated to command subsequent developments. This transition, which h...
Lydie Couturier,Juan Luna,Khalil Mazouni et al.
Lydie Couturier et al.
Multiscale analysis of morphogenesis requires to follow and measure in real-time the in vivo behaviour of large numbers of individual cells over long period of time. Despite recent progress, the large-scale automated tracking of cells in de...
Gina Hauptman,Marie C Reichert,Muna A Abdal Rhida et al.
Gina Hauptman et al.
Receptor proteins of the Roundabout (Robo) family regulate axon guidance decisions during nervous system development. Among the three Drosophila robo family genes (robo1, robo2 and robo3), robo2 displays a dynamic expression pattern and reg...
Dynamic movement and turnover of extracellular matrices during tissue development and maintenance [0.03%]
组织发生和维持过程中的细胞外基质动力学行为及周转率
Yutaka Matsubayashi
Yutaka Matsubayashi
Extracellular matrices (ECMs) are essential for the architecture and function of animal tissues. ECMs have been thought to be highly stable structures; however, too much stability of ECMs would hamper tissue remodelling required for organ d...
Studies of neurodegenerative diseases using Drosophila and the development of novel approaches for their analysis [0.03%]
采用果蝇研究神经退行性疾病及分析新方法的发展
Yohei Nitta,Atsushi Sugie
Yohei Nitta
The use of Drosophila in neurodegenerative disease research has contributed to the identification of modifier genes for the pathology. The basis for neurodegenerative disease occurrence in Drosophila is the conservation of genes across spec...
Ancestral dietary change alters the development of Drosophila larvae through MAPK signalling [0.03%]
祖先饮食变化通过MAPK信号通路改变果蝇幼虫发育
Samuel G Towarnicki,Neil A Youngson,Susan M Corley et al.
Samuel G Towarnicki et al.
Studies in a broad range of animal species have revealed phenotypes that are caused by ancestral life experiences, including stress and diet. Ancestral dietary macronutrient composition and quantity (over- and under-nutrition) have been sho...
Cell mechanics and cell-cell recognition controls by Toll-like receptors in tissue morphogenesis and homeostasis [0.03%]
toll样受体控制的细胞机械力及细胞间识别在组织形态建成和稳态维持中的作用
Daiki Umetsu
Daiki Umetsu
Signal transduction by the Toll-like receptors (TLRs) is conserved and essential for innate immunity in metazoans. The founding member of the TLR family, Drosophila Toll-1, was initially identified for its role in dorsoventral axis formatio...
A standardized nomenclature and atlas of the female terminalia of Drosophila melanogaster [0.03%]
拟南芥和果蝇性别二态性研究取得进展
Eden W McQueen,Mehrnaz Afkhami,Joel Atallah et al.
Eden W McQueen et al.
The model organism Drosophila melanogaster has become a focal system for investigations of rapidly evolving genital morphology as well as the development and functions of insect reproductive structures. To follow up on a previous paper outl...
Cutting edge technologies expose the temporal regulation of neurogenesis in the Drosophila nervous system [0.03%]
最新的技术揭示了神经干细胞在果蝇神经系统中的动态变化规律
Makoto Sato,Takumi Suzuki
Makoto Sato
During the development of the central nervous system (CNS), extremely large numbers of neurons are produced in a regular fashion to form precise neural circuits. During this process, neural progenitor cells produce different neurons over ti...
Interorgan communication through peripherally derived peptide hormones in Drosophila [0.03%]
果蝇通过外周来源的肽激素进行器官间通讯
Naoki Okamoto,Akira Watanabe
Naoki Okamoto
In multicellular organisms, endocrine factors such as hormones and cytokines regulate development and homoeostasis through communication between different organs. For understanding such interorgan communications through endocrine factors, t...