Orie Thomas Shafer
Orie Thomas Shafer
The field of Drosophila sleep research, which began 25 years ago, has identified more than 200 genes influencing sleep. In this review, I summarize the foundation of the field and the growing list of genes implicated in sleep regulation. I ...
Enhancing drug administration in Drosophila melanogaster: a method for using solid dispersions for improved solubility and bioavailability [0.03%]
改善模式生物小菜蛾和果蝇的药物处理方法学：固态分散技术提高难溶药剂溶解度及生物利用度的研究
Sunayn Cheku,Blase Rokusek,Mahesh Pattabiraman et al.
Sunayn Cheku et al.
Drosophila melanogaster is a widely used model organism for diseases such as Parkinson's disease, Alzheimer's disease, obesity, and diabetes. However, compound administration-based toxicological and behavioural studies on Drosophila have be...
An updated proteomic analysis of Drosophila haemolymph after bacterial infection [0.03%]
果蝇细菌感染后的血淋巴蛋白组学分析更新
Samuel Rommelaere,Fanny Schüpfer,Florence Armand et al.
Samuel Rommelaere et al.
Using an in-depth Mass Spectrometry-based proteomics approach, we provide a comprehensive characterization of the hemolymphatic proteome of adult flies upon bacterial infection. We detected and quantified changes in abundance of several kno...
Esther D Domenie,Paola Cusumano,Sara Montagnese et al.
Esther D Domenie et al.
The aim of the present study was to assess sleep timing in Drosophila melanogaster at different ages, within the setting of an enforced schedule of varying light-dark stimuli, simulating light exposure variations between four typical office...
Simon G Sprecher
Simon G Sprecher
Exploring the versatility of Drosophila melanogaster as a model organism in biomedical research: a comprehensive review [0.03%]
果蝇作为生物医学研究模式生物的多样性和应用性：全面综述
Ayomide Victor Atoki,Patrick Maduabuchi Aja,Tijjani Salihu Shinkafi et al.
Ayomide Victor Atoki et al.
Drosophila melanogaster is a highly versatile model organism that has profoundly advanced our understanding of human diseases. With more than 60% of its genes having human homologs, Drosophila provides an invaluable system for modelling a w...
A face-off between Smaug and Caspar modulates primordial germ cell count and identity in Drosophila embryos [0.03%]
Smaug和Caspar相互作用调控果蝇胚胎原始生殖细胞的数量和身份属性
Girish Deshpande,Subhradip Das,Adheena Elsa Roy et al.
Girish Deshpande et al.
Proper formation and specification of Primordial Germ Cells (PGCs) is of special significance as they gradually transform into Germline Stem Cells (GSCs) that are ultimately responsible for generating the gametes. Intriguingly, not only the...
A history of studies of reproductive isolation between Drosophila pseudoobscura and D. persimilis [0.03%]
DPS和DPH间生殖隔离的研究历史
Stewart Leigh,Michael G Ritchie
Stewart Leigh
Drosophila pseudoobscura and D. persimilis are a sister species pair that have been used as a model for studies of reproductive isolation and speciation for almost 100 years owing to their close evolutionary history, well characterized gene...
Effects of adaptation to crowded larval environment on the evolution of sperm competitive ability in males of Drosophila melanogaster [0.03%]
拥挤幼虫环境适应对果蝇黑腹属雄性精子竞争能力进化的影响
Rohit Kapila,Komal Maggu,Neetika Ahlawat et al.
Rohit Kapila et al.
Two of the most important environmental factors that affect the sperm competitive ability in males are the availability of resources and the socio-sexual environment. Numerous studies have investigated the individual effects of these factor...
A fast in situ hybridization chain reaction method in Drosophila embryos and ovaries [0.03%]
果蝇胚胎和卵巢中快速的原位杂交链反应法
Kyohei Mikami,Yasuhiro Kozono,Masaki Masukawa et al.
Kyohei Mikami et al.
The in situ hybridization chain reaction (isHCR) is a powerful method for visualizing mRNA in many species. We present a rapid isHCR method for Drosophila embryos and ovaries. Ethylene carbonate was added to the hybridization buffer to faci...