Correspondence of Drosophila polycomb group proteins with broad H3K27me3 silent domains [0.03%]
果蝇polycomb组蛋白与Broad H3K27精氨酸甲基转移酶沉默区域的对应关系
Youngsook L Jung,Hyuckjoon Kang,Peter J Park et al.
Youngsook L Jung et al.
Starving for more: Nutrient sensing by LIN-28 in adult intestinal progenitor cells [0.03%]
营养我还有更多想要感知：LIN-28在成年肠道干细胞中的作用
Arthur Luhur,Nicholas Sokol
Arthur Luhur
In this Extra View, we extend our recent work on the protein LIN-28 and its role in adult stem cell divisions. LIN-28 is an mRNA- and microRNA-binding protein that is conserved from worms to humans. When expressed ectopically, it promotes t...
Understanding the role of chromatin remodeling in the regulation of circadian transcription in Drosophila [0.03%]
解读染色质重塑在调节果蝇昼夜节律转录中的作用
Rosanna S Kwok,Vu H Lam,Joanna C Chiu
Rosanna S Kwok
Circadian clocks enable organisms to anticipate daily changes in the environment and coordinate temporal rhythms in physiology and behavior with the 24-h day-night cycle. The robust cycling of circadian gene expression is critical for prope...
Billel Benmimoun,Marc Haenlin,Lucas Waltzer
Billel Benmimoun
Drosophila lymph gland, a larval haematopoietic organ, has emerged as a popular model to study regulatory mechanisms controlling blood cell progenitor fate. In this organ, the Posterior Signaling Center (PSC), a small group of cells express...
Dinis J S Afonso,Daniel R Machado,Kyunghee Koh
Dinis J S Afonso
Sleep is essential for health and cognition, but the molecular and neural mechanisms of sleep regulation are not well understood. We recently reported the identification of TARANIS (TARA) as a sleep-promoting factor that acts in a previousl...
Shigeyuki Koshikawa
Shigeyuki Koshikawa
Animals have modular cis-regulatory regions in their genomes, and expression of a single gene is often regulated by multiple enhancers residing in such a region. In the laboratory, and also in natural populations, loss of an enhancer can re...
High throughput preparation of fly genomic DNA in 96-well format using a paint-shaker [0.03%]
利用震荡机在96孔板上高效提取果蝇基因组DNA
Michael Lang,Olga Nagy,Claus Lang et al.
Michael Lang et al.
Sample homogenization is an essential step for genomic DNA extraction, with multiple downstream applications in Molecular Biology. Genotyping hundreds or thousands of samples requires an automation of this homogenization step, and high thro...
Marta Marzullo,Maurizio Gatti
Marta Marzullo
Drosophila telomeres are maintained by transposition to chromosome ends of the HeT-A, TART and TAHRE retrotransposons, collectively designated as HTT. Although all Drosophila telomeres terminate with HTT arrays and are capped by the termini...
Jiongming Lu,Steven J Marygold,Walid H Gharib et al.
Jiongming Lu et al.
Aminoacyl-tRNA synthetases (aaRSs) ligate amino acids to their cognate tRNAs, allowing them to decode the triplet code during translation. Through different mechanisms aaRSs also perform several non-canonical functions in transcription, tra...
Mesenchymal to epithelial transition during tissue homeostasis and regeneration: Patching up the Drosophila midgut epithelium [0.03%]
组织稳态和再生过程中的间叶细胞到上皮细胞的转变：补丁修复果蝇中肠上皮细胞
Zeus A Antonello,Tobias Reiff,Maria Dominguez
Zeus A Antonello
Stem cells are responsible for preserving morphology and function of adult tissues. Stem cells divide to self-renew and to generate progenitor cells to sustain cell demand from the tissue throughout the organism's life. Unlike stem cells, t...