H Bahar Sahin,Omer Faruk Karatas,Valeria Specchia et al.
H Bahar Sahin et al.
Aubergine is an RNA-binding protein of the Piwi clade, functioning in germline in the piRNA pathway that silences transposons and repetitive sequences. Several mutations of this gene exist, but they mostly result in truncated proteins or co...
Proteomic changes in response to crystal formation in Drosophila Malpighian tubules [0.03%]
果蝇Malpigen管晶体形成过程中的蛋白质组学变化
Vera Y Chung,Rebecca Konietzny,Philip Charles et al.
Vera Y Chung et al.
Kidney stone disease is a major health burden with a complex and poorly understood pathophysiology. Drosophila Malpighian tubules have been shown to resemble human renal tubules in their physiological function. Herein, we have used Drosophi...
Mitochondrial retrograde signaling in the Drosophila nervous system and beyond [0.03%]
线粒体逆向信号在果蝇神经系统的内外作用机制研究
Olivia F Duncan,Joseph M Bateman
Olivia F Duncan
Mitochondrial dysfunction has been suggested to contribute to neurodegenerative diseases, including Alzheimer and Parkinson disease. Cells respond to changes in the functional state of mitochondria via retrograde signaling pathways from the...
A rapid, gentle and scalable method for dissociation and fluorescent sorting of imaginal disc cells for mRNA sequencing [0.03%]
一种快速、温和且可扩展的方法用于 imaginal disc 组织的消化和荧光分选以进行转录组测序研究
Sumbul Jawed Khan,Syeda Nayab Fatima Abidi,Yuan Tian et al.
Sumbul Jawed Khan et al.
Dissociation of imaginal disc cells has been carried out previously to enable flow cytometry and cell sorting to analyze cell cycle progression, cell size, gene expression, and other aspects of imaginal tissues. However, the lengthy dissoci...
Regulated protein depletion by the auxin-inducible degradation system in Drosophila melanogaster [0.03%]
果蝇中由生长素诱导的降解系统介导的蛋白质耗尽
Martina Trost,Ariane C Blattner,Christian F Lehner
Martina Trost
The analysis of consequences resulting after experimental elimination of gene function has been and will continue to be an extremely successful strategy in biological research. Mutational elimination of gene function has been widely used in...
Bioinformatic analyses of sense and antisense expression from terminal inverted repeat transposons in Drosophila somatic cells [0.03%]
染色体末端倒位重复序列在果蝇体细胞中的正负链表达及生物信息学分析
Andrew W Harrington,Mindy Steiniger
Andrew W Harrington
Understanding regulation of transposon movement in somatic cells is important as mobile elements can cause detrimental genomic rearrangements. Generally, transposons move via one of 2 mechanisms; retrotransposons utilize an RNA intermediate...
A triangular connection between Cyclin G, PP2A and Akt1 in the regulation of growth and metabolism in Drosophila [0.03%]
Drosophila中cyclin G、PP2A和Akt1之间的三角联系在生长及代谢调控中的作用
Patrick Fischer,Anette Preiss,Anja C Nagel
Patrick Fischer
Size and weight control is a tightly regulated process, involving the highly conserved Insulin receptor/target of rapamycin (InR/TOR) signaling cascade. We recently identified Cyclin G (CycG) as an important modulator of InR/TOR signaling a...
Coupling of growth to nutritional status: The role of novel periphery-to-brain signaling by the CCHa2 peptide in Drosophila melanogaster [0.03%]
生长与营养状态的耦合：Drosophila melanogaster中新型周边至大脑信号传导CCHa2肽的作用
Hiroko Sano
Hiroko Sano
The coupling of growth to nutritional status is an important adaptive response of living organisms to their environment. For this ability, animals have evolved various strategies, including endocrine systems that respond to changing nutriti...
Ultrastructural features of spermatozoa and their phylogenetic application in Zaprionus (Diptera, Drosophilidae) [0.03%]
Zaprionus精子的超微结构特征及其在系统发育中的应用（双翅目，果蝇科）
Letícia do Nascimento Andrade de Almeida Rego,Kaio Cesar Chaboli Alevi,Maria Tercília Vilela de Azeredo-Oliveira et al.
Letícia do Nascimento Andrade de Almeida Rego et al.
The genus Zaprionus consists of approximately 60 species of drosophilids that are native to the Afrotropical region. The phylogenetic position of Zaprionus within the Drosophilidae family is still unresolved. In the present study, ultrastru...
Testing candidate genes for attention-deficit/hyperactivity disorder in fruit flies using a high throughput assay for complex behavior [0.03%]
利用果蝇行为高通量检测系统筛查注意缺陷多动症候选基因
Palle Duun Rohde,Lisbeth Strøm Madsen,Sandra Marie Neumann Arvidson et al.
Palle Duun Rohde et al.
Fruit flies are important model organisms for functional testing of candidate genes in multiple disciplines, including the study of human diseases. Here we use a high-throughput locomotor activity assay to test the response on activity beha...