Annick Sawala,Alex P Gould
Annick Sawala
Sexual size dimorphism (SSD), a sex difference in body size, is widespread throughout the animal kingdom, raising the question of how sex influences existing growth regulatory pathways to bring about SSD. In insects, somatic sexual differen...
Dietary management and physical exercise can improve climbing defects and mitochondrial activity in Drosophila melanogaster parkin null mutants [0.03%]
饮食管理和身体锻炼可以改善果蝇Parkin基因缺陷引起的运动缺陷和线粒体活性降低
Rijan Bajracharya,J William O Ballard
Rijan Bajracharya
Physical exercise can improve gait, balance, tremor, flexibility, grip strength and motor coordination in Parkinson's disease (PD) patients. Several lines of evidence have also shown the therapeutic potential of dietary management and suppl...
bantam microRNA is a negative regulator of the Drosophila decapentaplegic pathway [0.03%]
微小RNA bantam是果蝇decapentaplegic通路的负调控因子
Nanci S Kane,Mehul Vora,Richard W Padgett et al.
Nanci S Kane et al.
Decapentaplegic (Dpp), the Drosophila homolog of the vertebrate bone morphogenetic protein (BMP2/4), is crucial for patterning and growth in many developmental contexts. The Dpp pathway is regulated at many different levels to exquisitely c...
Keeping it tight: The relationship between bacterial dysbiosis, septate junctions, and the intestinal barrier in Drosophila [0.03%]
紧密关联：果蝇中细菌失调、分体连接和肠道屏障之间的关系
Martin Resnik-Docampo,Vivien Sauer,Joseph M Schinaman et al.
Martin Resnik-Docampo et al.
Maladaptive changes in the intestinal flora, typically referred to as bacterial dysbiosis, have been linked to intestinal aging phenotypes, including an increase in intestinal stem cell (ISC) proliferation, activation of inflammatory pathwa...
Mariana Muzzopappa,Marco Milán
Mariana Muzzopappa
The growth of epithelial tumors is often governed by cell interactions with the surrounding stroma. Drosophila has been instrumental in identifying the relevant molecular elements mediating these interactions. Of note is the role of the TNF...
Combining morphology and molecular data to improve Drosophila paulistorum (Diptera, Drosophilidae) taxonomic status [0.03%]
结合形态和分子数据以改善斑翅果蝇属保罗氏群（双翅目，果蝇族）的分类地位
Rebeca Zanini,Mário Josias Müller,Gilberto Cavalheiro Vieira et al.
Rebeca Zanini et al.
The willistoni species subgroup has been the subject of several studies since the latter half of the past century and is considered a Neotropical model for evolutionary studies, given the many levels of reproductive isolation and different ...
The COP9 signalosome inhibits Cullin-RING E3 ubiquitin ligases independently of its deneddylase activity [0.03%]
COP9信号体通过其去Nedd化活性独立抑制泛素连接酶Culne-RING类蛋白
Annabelle Suisse,Miklós Békés,Tony T Huang et al.
Annabelle Suisse et al.
The COP9 signalosome inhibits the activity of Cullin-RING E3 ubiquitin ligases by removing Nedd8 modifications from their Cullin subunits. Neddylation renders these complexes catalytically active, but deneddylation is also necessary for the...
Compromising asymmetric stem cell division in Drosophila central brain: Revisiting the connections with tumorigenesis [0.03%]
果蝇中枢脑干细胞的不对称分裂偏向性及其与肿瘤的关系探究
Ana Carmena
Ana Carmena
Asymmetric cell division (ACD) is an essential process during development for generating cell diversity. In addition, a more recent connection between ACD, cancer and stem cell biology has opened novel and highly intriguing venues in the fi...
FijiWingsPolarity: An open source toolkit for semi-automated detection of cell polarity [0.03%]
斐济翼极性：一个用于半自动检测细胞极性的开源工具包
Leonard L Dobens,Anna Shipman,Jeffrey D Axelrod
Leonard L Dobens
Epithelial cells are defined by apical-basal and planar cell polarity (PCP) signaling, the latter of which establishes an orthogonal plane of polarity in the epithelial sheet. PCP signaling is required for normal cell migration, differentia...
Identifying the minimum number of microsatellite loci needed to assess population genetic structure: A case study in fly culturing [0.03%]
通过果蝇培养例证分析鉴定用于评估种群遗传结构的最少微卫星基因座数量的方法
Wolfgang Arthofer,Carina Heussler,Patrick Krapf et al.
Wolfgang Arthofer et al.
Small, isolated populations are constantly threatened by loss of genetic diversity due to drift. Such situations are found, for instance, in laboratory culturing. In guarding against diversity loss, monitoring of potential changes in popula...