The cytoskeleton of the neuron--an essay in celebration of Paul Letourneau's career [0.03%]
神经元的细胞骨架——向保罗·乐唐庆祝其职业生涯的文章
Daphney C Jean,Mark M Black,Peter W Baas
Daphney C Jean
The neuronal cytoskeleton consists of microtubules, actin filaments, neurofilaments, and an array of accessory proteins that regulate and modify these three main filament systems. This essay celebrates the career of Paul Letourneau, a pione...
Dynamic morphometrics reveals contributions of dendritic growth cones and filopodia to dendritogenesis in the intact and awake embryonic brain [0.03%]
动态形态测量揭示了完整清醒的胚胎大脑中树突生长锥和丝状伪足在树突发生中的作用
Sharmin Hossain,D Sesath Hewapathirane,Kurt Haas
Sharmin Hossain
Using in vivo rapid and long-interval two-photon time-lapse imaging of brain neuronal growth within the intact and unanesthetized Xenopus laevis tadpole, we characterize dynamic dendritic growth behaviors of filopodia, branches, and dendrit...
Extracellular matrix molecules, their receptors, and secreted proteases in synaptic plasticity [0.03%]
细胞外基质分子、其受体和分泌蛋白酶在突触可塑性中的作用
Jakub Wlodarczyk,Irina Mukhina,Leszek Kaczmarek et al.
Jakub Wlodarczyk et al.
Neural cells secrete diverse molecules, which accumulate in the extracellular space and form the extracellular matrix (ECM). Interactions between cells and the ECM are well recognized to play the crucial role in cell migration and guidance ...
Valerie J Milton,Sean T Sweeney
Valerie J Milton
Oxidative stress, caused by increased levels of reactive oxidative species (ROS), is considered a major contributor to the aging process. How oxidative stress may bring about changes to structures and function in the aging brain is poorly u...
Enhanced expression of tubulin-specific chaperone protein A, mitochondrial ribosomal protein S27, and the DNA excision repair protein XPACCH in the song system of juvenile male zebra finches [0.03%]
腔棘鱼体内特定稳定蛋白A、线粒体核糖体蛋白S27及DNA切取修复蛋白XPACCH在小凤头鸟鹛歌唱系统中的表达增强
Linda M Qi,Margaret Mohr,Juli Wade
Linda M Qi
Recent evidence suggests that sexual dimorphisms in the zebra finch song system and behavior arise due to factors intrinsic to the brain, rather than being solely organized by circulating steroid hormones. The present study examined express...
14-3-3 proteins regulate retinal axon growth by modulating ADF/cofilin activity [0.03%]
14-3-3蛋白通过调控ADF/可调扭动蛋白活性来调节视网膜轴突生长
Byung C Yoon,Krishna H Zivraj,Laure Strochlic et al.
Byung C Yoon et al.
Precise navigation of axons to their targets is critical for establishing proper neuronal networks during development. Axon elongation, whereby axons extend far beyond the site of initiation to reach their target cells, is an essential step...
Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke [0.03%]
细胞外基质和受体在血脑屏障形成及卒中中的作用
Kim M Baeten,Katerina Akassoglou
Kim M Baeten
The blood-brain barrier (BBB) is formed primarily to protect the brain microenvironment from the influx of plasma components, which may disturb neuronal functions. The BBB is a functional unit that consists mainly of specialized endothelial...
Role of extracellular matrix proteins and their receptors in the development of the vertebrate neuromuscular junction [0.03%]
脊椎动物神经肌肉突触发育中细胞外基质蛋白及其受体的作用
Neha Singhal,Paul T Martin
Neha Singhal
The vertebrate neuromuscular junction (NMJ) remains the best-studied model for understanding the mechanisms involved in synaptogenesis, due to its relatively large size, its simplicity of patterning, and its unparalleled experimental access...
Marla B Feller,Y Henry Sun
Marla B Feller
Gaia Tavosanis
Gaia Tavosanis
Dendrites represent the compartment of neurons primarily devoted to collecting and computating input. Far from being static structures, dendrites are highly dynamic during development and appear to be capable of plastic changes during the a...