Adolescent White Matter Maturation Mediates Epigenetic Associations With Cognitive Development [0.03%]
表观遗传与认知发育的关系通过青少年白质成熟来介导
Dawn Jensen,Jiayu Chen,Jessica A Turner et al.
Dawn Jensen et al.
One hallmark of brain maturation in adolescence is increased myelination (fractional anisotropy [FA]) of the axons, although the epigenetic drivers of this stage of neurodevelopment are as yet poorly understood. Our previous study of a long...
Targeting Brain Plasticity: Vagal Nerve Stimulation as a Therapy for Autism-Like Symptoms in a Valproic Acid Mouse Model [0.03%]
靶向大脑可塑性：迷走神经刺激作为治疗,valproic酸小鼠自闭症模型的治疗方法
Aysen Calikusu,Merve Sevgi Ince,Hayrunnisa Bolay et al.
Aysen Calikusu et al.
Autism spectrum disorder (ASD) is a multifactorial neurodevelopmental condition defined by social deficits, stereotypical or repetitive behaviors, and anxiety. This study evaluates the therapeutic potential of transauricular vagal nerve sti...
A Review Study on Computational Insights Into Transition Metal Complex Cytotoxicity in Neurobiology [0.03%]
计算视角下过渡金属化合物神经毒性的研究进展及其作用机制综述
Roopashree B
Roopashree B
Transition metal complexes (TMCs) have emerged as promising agents in neurotherapeutics due to their redox activity, coordination flexibility, and ability to interact with biomolecular targets. However, their cytotoxic effects on neural tis...
Chromatin Profiling Reveals Distinct Male and Female Trajectories for Developmental Learning Potential [0.03%]
染色质分析揭示了男性和女性在发育学习潜能方面的不同轨迹
Grant W Kunzelman,Alice Batistuzzo,Sarah E London
Grant W Kunzelman
Adult patterns of behavior can often be explained by developmental experiences. In some cases, developmental experience can have permanent influence on brain and behavior only during specific ages; these phases are called critical or sensit...
Greater Increase in Hippocampal Activity During the Early Postnatal Period After Preterm Birth Is Associated With Better Cognitive and Motor Outcomes at 18 Months [0.03%]
早产出生后产后早期海马活动增加与18个月时较好的认知和运动结果相关
Anika Guha,Sharon K Hunter,Kristina T Legget et al.
Anika Guha et al.
Establishing a proper balance between neuronal excitation (E) and inhibition (I) is essential for healthy brain development, with alterations in this dynamic linked to neurodevelopmental disorders. Animal models suggest that hippocampal act...
Investigating the Role of Zebrafish Retinoschisin Homologs Rs1a and Rs1b During Retinal Development [0.03%]
斑马鱼视网膜发育过程中视黄蛋白Rs1a和Rs1b同源物的作用研究
Isa van der Veen,Céline Koster,Jacoline B Ten Brink et al.
Isa van der Veen et al.
Deficiency in the retinoschisin protein (RS1) causes X-linked juvenile retinoschisis (XLRS), a retinal degenerative disease that disrupts retinal layers and forms cystic cavities. In addition to its structural function, RS1 is believed to p...
Astrocytes and Microglia in Alzheimer's Disease: Friends, Foes, or Both? [0.03%]
阿尔茨海默病中的星形胶质细胞和小胶质细胞：是友军、敌军还是两者兼有？
Amit Sharma,Bhavin Parekh,Vinay Patil et al.
Amit Sharma et al.
Alzheimer's disease (AD), the most prevalent form of dementia, is neuropathologically defined by the accumulation of extracellular amyloid-beta (Aβ) plaques and intracellular neurofibrillary tangles of hyperphosphorylated tau. Although tra...
Facial Morphometric Features in Autism Spectrum Disorder: Preliminary Findings From Canonical Discriminant Analysis [0.03%]
典型判别分析下的自闭症光谱系面部形态学特征的初步研究结果
Fethiye Kılıçaslan,Serdar Babacan,Bahaddin Çolak et al.
Fethiye Kılıçaslan et al.
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by impairments in social communication and the presence of restricted, repetitive behaviors. Although there is no cure for ASD, early diagnosis and evidence-base...
Effect of 900 MHz Electromagnetic Field Exposure During Different Trimesters of Pregnancy on TRPM2-Mediated Ferroptosis and Neurotoxicity in the Trigeminal Ganglion of Rats: Protective Role of Ferrostatin-1 [0.03%]
900兆赫电磁场暴露对不同孕期大鼠三叉神经节TRPM2介导的铁死亡和神经毒性的影响：Ferrostatin-1的保护作用
Yener Yazğan,Kıymet Kübra Tüfekci,Betül Yazğan et al.
Yener Yazğan et al.
Electromagnetic field (EMF) exposure, unavoidable in modern life, is linked to oxidative stress and ferroptosis, processes linked to neurodevelopmental disorders. This study investigated the effects of EMF exposure during different pregnanc...
Silent Synapses in Multiple Sclerosis: From Synaptic Dysfunction to Reactivation-Based Therapies-A Narrative Review of Cognitive and Neuroplasticity Outcomes [0.03%]
沉默突触在多发性硬化症中的作用：从突触功能障碍到基于再激活的疗法-认知和神经可塑性结果叙事综述
Zinab Alatawi
Zinab Alatawi
Silent synapses in multiple sclerosis (MS) represent a key yet underexplored concept in the pathology of this disease, playing a crucial role in cognitive impairments and reduced neuroplasticity. These synapses, due to the inactivity of AMP...