Cannabis Oil Protects Against Valproic Acid-Induced Autism Spectrum Disorder by Reducing Oxidative Stress [0.03%]
大麻油通过减少氧化应激来保护伏隔核酸诱导的自闭症谱系障碍
Faiza Ali,Adeeb Shehzad,Raheem Shahzad et al.
Faiza Ali et al.
Autism spectrum disorder (ASD) is characterized by persistent problems in speech, social interaction, restricted and repetitive behavior patterns, lack of interest, and intellectual disabilities. Currently, there is no effective treatment a...
Michael R Deschenes,Max Rackley,Sophie Fernandez et al.
Michael R Deschenes et al.
The neuromuscular junction (NMJ) is the synapse that enables the requisite electrical communication between the motor nervous system and the myofibers that respond to such electrical stimulation with movement and force development. Changes ...
Distinct Developmental Programs Displayed by the Xenopus Tadpole Accessory Optic System and Retinotectal Projection [0.03%]
非洲爪蟾副眼和视网膜-顶扃核投射的发育程序的区别
Uwemedimo G Udoh,Kaiyuan Zheng,John R Bruno et al.
Uwemedimo G Udoh et al.
The retinotectal projection, the direct synapse between retinal ganglion cells (RGCs) of the eye and tectal neurons of the optic tectum, is a major component of the amphibian visual system. A model of circuit formation, this projection has ...
Elevated Serum Histamine N-Methyltransferase Levels Are Associated With the Pathophysiology of Major Depressive Disorder: A Case-Control Study [0.03%]
血清组胺N-甲基转移酶水平升高与重大抑郁障碍的病理生理学相关：一项病例对照研究
Mariya Akter,Dibbo Protim Ghosh,Toha Tasnem et al.
Mariya Akter et al.
Major depressive disorder (MDD) is a common neuropsychiatric disorder with persistent low mood, feelings of weakness, and a lack of interestin daily tasks. Histamine N-methyltransferase (HNMT) protein is involved in the inactivation process...
The Rare Syndrome Aicardi-Goutières 4: A Case Report and Literature Review [0.03%]
艾卡德里-戈泰尔兹综合征4型1例报告及文献复习
Hilal Aydin,Hilmi Bolat
Hilal Aydin
Aicardi-Goutières syndrome (AGS) is a genetically heterogeneous type of interferonopathy resulting from defects in the processing or sensing of nucleic acids. The AGS phenotype encompasses a broad range of neurological and non-neurological...
Maternal Treadmill Exercise and Zinc Supplementation Alleviate Prenatal Stress-Induced Cognitive Deficits and Restore Neurological Biomarkers in Offspring: A Study on Male Rats Aged 30 and 90 Days [0.03%]
母体跑步机运动和锌补充剂可缓解 prenatal stress 引起的大鼠子代认知缺陷并恢复其神经生物标志物：30 和 90 天龄雄性大鼠的研究
Sina Fatehfar,Parsa Sameei,Naseh Abdollahzade et al.
Sina Fatehfar et al.
The detrimental effects of prenatal stress (PS) on offspring's neurological and behavioral outcomes are well documented. However, strategies to mitigate these effects are underexplored. This study examines whether prenatal zinc supplementat...
Azilsartan Confers Protection Against Kainic Acid-Induced Hippocampal Neuron Damage by Upregulating Sirt3/Sod2 Pathway [0.03%]
通过上调Sirt3/Sod2通路阿利沙坦对戊酸钠诱导的海马神经元损伤具有保护作用
Hui-Hui Lv,Mao-Ying Xia
Hui-Hui Lv
Epilepsy refers to a diverse group of neurological pathologies, coupled with a significant worldwide impact. Azilsartan, an angiotensin receptor blocker, is broadly applied as an antihypertensive medication. Considering that the neuroprotec...
Cordycepin Ameliorates Kainic Acid-Induced HT22 Cell Neurotoxicity by Activating GPR120-Mediated Mitophagy [0.03%]
玉米素通过激活GPR120介导的线粒体自噬来改善奎尼酸诱导的HT22细胞神经毒性
Yongzhi San,Minghua Wang
Yongzhi San
Background: Mitophagy is important for normal neural activity. Epilepsy is intimately linked to neurotoxicity due to mitochondrial dysfunction. Cordycepin (Cor) has been shown to exert neuroprotective effects. This study ...
The Mechanism Behind the Therapeutic Role of Alpha-Tocopherol in Mitigating Hypobaric Hypoxia-Induced Eye Defect in Drosophila melanogaster [0.03%]
α-生育酚通过抗氧化应激途径减轻果蝇高原缺氧引起的眼缺陷的治疗机制研究
Seekha Naik,Smruti Sudha Biswal,Monalisa Mishra
Seekha Naik
Hypoxia, or low oxygen levels, is linked to several pathological disorders, including retinopathies. Retina being a metabolically active tissue, low oxygen levels resulted in retinal degradation. The developmental perspective of hypobaric h...
Raul Miranda-Ojeda,Anuksha Wickramasinghe,Georgios Ntolkeras et al.
Raul Miranda-Ojeda et al.
The term "neurodiversity" refers to the natural heterogeneity in human neurological functioning, which includes neurodevelopmental differences and other mental health conditions (e.g., autism spectrum disorder [ASD], attention-deficit hyper...