Characterization of Neural Stem Cells of the Human Embryonic Fetus Across Regions of the Central Nervous System and Through Standard Gestation Period Assessments [0.03%]
人胚胎儿中枢神经系统各区域标准胎龄评估的神经干细胞特征分析
Yu Mi Park,Hyun Young Kim
Yu Mi Park
In this study, the characteristics of human embryonic fetuses aborted due to ectopic pregnancy were preliminarily evaluated on the basis of gestational age (GA), crown-rump - length (CRL), and their carnegie stage (CS). Further, we attempte...
Kristof Laszlo,Zuzana Bacova,Dora Zelena et al.
Kristof Laszlo et al.
Although the early signs of autism spectrum disorder (ASD) are widely studied, the significant ambiguity and heterogeneity in symptoms require the comparison of available models, approaches, and the search for common denominators and key in...
Genetic Inactivation of the Serotonin Transporter Dysregulates Expression of Neurotransmission Genes and Genome-Wide DNA Methylation Levels in the Medial Prefrontal Cortex of Male Rats During Postnatal Development [0.03%]
五羟色胺转运蛋白基因失活扰乱雄性大鼠产后发育前期背侧前额叶皮层神经递质受体基因及全基因组DNA甲基化水平表达模式
Yvet Kroeze,Martin Oti,Roel H M Cooijmans et al.
Yvet Kroeze et al.
Reduced expression of the serotonin transporter (5-hydroxytryptamine transporter, 5-HTT) in early life has been associated with a delay in postnatal brain development and endophenotypes of a variety of neuropsychiatric and neurodevelopmenta...
Exploring the Role of NLRP3 in Neurodegeneration: Cutting-Edge Therapeutic Strategies and Inhibitors [0.03%]
NLRP3在神经退行性疾病中的作用探索：前沿治疗策略和抑制剂研究
Mohammed Ahmed Mustafa,Pooja Bansal,M S Pallavi et al.
Mohammed Ahmed Mustafa et al.
Inflammasomes, particularly the NLRP3 inflammasome, play a pivotal role in mediating neuroinflammation in neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), multiple s...
Islet-2 Is Required for the Survival of Islet-Expressing Retinal Ganglion Cells but Not for Their Pathfinding to the Contralateral Dorsal Lateral Geniculate Nucleus [0.03%]
索拉素-2对于表达索拉素的视网膜神经节细胞的存活是必需的，但对其导向对侧外侧膝状体核并不是必需的
Sadaf Abed,David A Feldheim
Sadaf Abed
Retinal ganglion cells (RGCs) exhibit remarkable diversity owing to their expression of developmentally expressed transcription factors. Many transcription factors are expressed in unique RGC populations, but their roles within these popula...
GATA Transcription Factors: A Cross-Road for Erythropoiesis, Neurodevelopment, and Synucleinopathies [0.03%]
GATA转录因子：红细胞生成、神经发育和突触核蛋白病的交汇点
Francesco Bellomi,Claudia Caturano,Viola Velardi et al.
Francesco Bellomi et al.
Alpha-synuclein (α-syn), a 140 amino acid protein, is abundantly expressed in the central nervous system (CNS) and in the erythrocytes, playing a pivotal role in the pathogenesis of Parkinson's disease (PD) and other synucleinopathies. Amo...
Disruption of Embryogenesis Biomarkers: A Critical Issue for Autism Therapeutics [0.03%]
胚胎发生生物标志物的破坏：自闭症治疗的关键问题
Abdulla A Al-Dulaimi,Turakulov Rustam,Mahmood Jawad et al.
Abdulla A Al-Dulaimi et al.
Recent advancements in the field of autism research have led to significant progress in identifying biomarkers associated with autism spectrum disorder (ASD). This article provides a comprehensive update on the current landscape of biomarke...
Maternal Stress and Maternal Microbiome Manipulations Remodel Offspring Medial Prefrontal Cortex in a Sex-Dependent Manner [0.03%]
母体压力和母体微生物群的操作以性别依赖的方式重塑后代腹内侧前额叶皮层结构
Luke Gohmann,Jessica A Cusick,Gregory E Demas et al.
Luke Gohmann et al.
Maternal stress and disruptions of the maternal microbiome during development can have profound organizational effects on the brain and behavior of offspring. We have previously demonstrated that these manipulations have marked, sex-depende...
Effects of the Missense Variants on Complete Phenotype and Splicing Variant on Severe Growth Retardation in the BPTF Gene [0.03%]
BPTF基因错义突变对完整表型及剪切变异对严重生长发育迟缓的影响
Gül Ünsel-Bolat,Hamide Betul Gerik-Celebi,Betül Diler Durgut et al.
Gül Ünsel-Bolat et al.
Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies (NEDDFL, OMIM no #617755) is an ultra-rare syndrome associated with heterozygous pathogenic variants in the BPTF gene. Haploinsufficiency of the BPTF gene, a chrom...
Mangrove-Crab Blood Cells Proliferate In Vitro and Display Neuronal Proteins Following Pituitary-Extract Stimulus [0.03%]
滩涂蟳的血细胞体外增殖及其对脑下垂体提取物刺激产生神经蛋白反应
Inês Júlia Ribas Wajsenzon,Isadora Santos de Abreu,Carlos Augusto Borges de Andrade Gomes et al.
Inês Júlia Ribas Wajsenzon et al.
In this study we propose a cell-culture protocol to better comprehend the involvement of immune/blood cells (hemocytes) in the adult neurogenesis of crustaceans. We examined whether the hemocytes of the crab Ucides cordatus may develop into...