Oligodendrocytes and myelin: Active players in neurodegenerative brains? [0.03%]
少突胶质细胞和髓鞘：神经退行性大脑中的活跃参与者？
Jing-Fei Chen,Fei Wang,Nan-Xing Huang et al.
Jing-Fei Chen et al.
Oligodendrocytes (OLs) are a major type of glial cells in the central nervous system that generate multiple myelin sheaths to wrap axons. Myelin ensures fast and efficient propagation of action potentials along axons and supports neurons wi...
Influence of developmental nicotine exposure on serotonergic control of breathing-related motor output [0.03%]
发育性尼古丁暴露对5-羟色胺能控制呼吸运动的影响
Lila Wollman,Andrew Hill,Brady Hasse et al.
Lila Wollman et al.
Serotonin plays an important role in the development of brainstem circuits that control breathing. Here, we test the hypothesis that developmental nicotine exposure (DNE) alters the breathing-related motor response to serotonin (5HT). Pregn...
Kang Zheng,Hao Huang,Junlin Yang et al.
Kang Zheng et al.
Astrocytes are the most abundant cell type in the central nervous system, carrying out a wide spectrum of biological functions. During early development, neural progenitor cells in the ventricular zone first produce neurons, followed by mac...
Regulation of axon pruning of mossy fiber projection in hippocampus by CRMP2 and CRMP4 [0.03%]
CRMP2和CRMP4调节海马区苔藓纤维投射的轴突修剪作用
Yurika Nakanishi,Satoshi Akinaga,Koki Osawa et al.
Yurika Nakanishi et al.
Axon pruning facilitates the removal of ectopic and misguided axons and plays an important role in neural circuit formation during brain development. Sema3F and its receptor neuropilin-2 (Nrp2) have been shown to be involved in the stereoty...
Manling Xie,Shunyi Zhao,Dale B Bosco et al.
Manling Xie et al.
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is an aggressive motor neuron degenerative disease characterized by selective loss of both upper and lower motor neurons. The mechanisms underlying disease initiation ...
Lijuan Zhang,Yue Cao,Xin Zhang et al.
Lijuan Zhang et al.
Microglia are important immune cells in the central nervous system. There is growing interest in the study of microglia due to their implication in neurodevelopment, acute injury, and neuropsychiatric disorders. They undergo birth, death, a...
Effect of lncRNA H19 on nerve degeneration and regeneration after sciatic nerve injury in rats [0.03%]
长链非编码RNA H19对坐骨神经损伤大鼠的神经退变及再生的影响
Yuting Li,Min Cai,Yumei Feng et al.
Yuting Li et al.
Hundreds of millions of people worldwide suffer from peripheral nerve damage resulting from car accidents, falls, industrial accidents, residential accidents, and wars. The purpose of our study was to further investigate the effects of Wall...
Interferon regulatory factor-7 is required for hair cell development during zebrafish embryogenesis [0.03%]
干扰素调节因子-7对于斑马鱼胚胎发育期间的毛细胞发育是必需的
Song-Qun Hu,Hui-Min Xu,Fu-Ping Qian et al.
Song-Qun Hu et al.
Interferon regulatory factor-7 (IRF7) is an essential regulator of both innate and adaptive immunity. It is also expressed in the otic vesicle of zebrafish embryos. However, any role for irf7 in hair cell development was uncharacterized. Do...
Novel localizations of TRPC5 channels suggest novel and unexplored roles: A study in the chick embryo brain [0.03%]
TRPC5通道的新定位提示了新的未探索的作用：鸡胚脑中的一个研究
Sharifuddin Rifat Ahmed,Elise Liu,Alissa Yip et al.
Sharifuddin Rifat Ahmed et al.
Mammalian TRPC5 channels are predominantly expressed in the brain, where they increase intracellular Ca2+ and induce depolarization. Because they augment presynaptic vesicle release, cause persistent neural activity, and show constitutive a...
Long-lasting implications of embryonic exposure to alcohol: Insights from zebrafish research [0.03%]
胚胎期接触酒精的长期影响：来自斑马鱼研究的启示
José Henrique Cararo,Eduardo Pacheco Rico
José Henrique Cararo
The harmful consumption of ethanol is associated with significant health problems and social burdens. This drug activates a complex network of reward mechanisms and habit formation learning that is supposed to contribute to the consumption ...