Hongai Xia,Donald F Ready
Hongai Xia
Drosophila photoreceptors (R cells) are an extreme instance of sensory membrane amplification via apical microvilli, a widely deployed and deeply conserved operation of polarized epithelial cells. Developmental rotation of R cell apices ali...
Expression and rapid experience-dependent regulation of type-A GABAergic receptors in the songbird auditory forebrain [0.03%]
鸣鸟听觉前脑GABAA受体的表达及快速经验依赖性调节
Jin Kwon Jeong,Thomas A Terleph,Kaiping Burrows et al.
Jin Kwon Jeong et al.
GABAergic transmission influences sensory processing and experience-dependent plasticity in the adult brain. Little is known about the functional organization of inhibitory circuits in the auditory forebrain of songbirds, a robust model ext...
Petrina A Georgala,Catherine B Carr,David J Price
Petrina A Georgala
Pax6 encodes a highly conserved transcriptional regulator with two DNA-binding motifs, a paired domain and a paired-like homeodomain. Humans carrying PAX6 loss-of-function mutations suffer from abnormal development of the eyes (congenital a...
Krishna V Melnattur,Chi-Hon Lee
Krishna V Melnattur
Both insect and vertebrate visual circuits are organized into orderly arrays of columnar and layered synaptic units that correspond to the array of photoreceptors in the eye. Recent genetic studies in Drosophila have yielded insights into t...
Long-range signaling systems controlling glial migration in the Drosophila eye [0.03%]
控制果蝇眼睛中小胶细胞迁移的远距离信号系统
Yeliz Yuva-Aydemir,Christian Klämbt
Yeliz Yuva-Aydemir
The Drosophila compound eye comprises about 750 individual ommatidia arranged into an almost crystalline array. The eye is not needed for viability and thus served as a favorite model organ to decipher many signaling systems controlling div...
Bernd Goellner,Hermann Aberle
Bernd Goellner
The cytoskeleton forms the backbone of neuronal architecture, sustaining its form and size, subcellular compartments and cargo logistics. The synaptic cytoskeleton can be categorized in the microtubule-based core cytoskeleton and the cortic...
Neil Dani,Kendal Broadie
Neil Dani
Synapse formation is driven by precisely orchestrated intercellular communication between the presynaptic and the postsynaptic cell, involving a cascade of anterograde and retrograde signals. At the neuromuscular junction (NMJ), both neuron...
Heparan sulfate proteoglycan specificity during axon pathway formation in the Drosophila embryo [0.03%]
果蝇胚胎中轴突路径形成过程中硫酸肝素蛋白多糖的特异性
Ashley D Smart,Meredith M Course,Joel Rawson et al.
Ashley D Smart et al.
Axon guidance is influenced by the presence of heparan sulfate (HS) proteoglycans (HSPGs) on the surface of axons and growth cones (Hu, [2001]: Nat Neurosci 4:695-701; Irie et al. [2002]: Development 129:61-70; Inatani et al. [2003]: Scienc...
Joshua G Corbin,Simon J B Butt
Joshua G Corbin
Interneurons, which release the neurotransmitter γ-aminobutyric acid (GABA), are the major inhibitory cells of the central nervous system (CNS). Despite comprising only 20-30% of the cerebral cortical neuronal population, these cells play ...
A functional scaffold of CNS neurons for the vertebrates: the developing Xenopus laevis spinal cord [0.03%]
脊椎动物CNS神经元的功能支架：非洲爪蟾发育中的脊髓
Alan Roberts,Wen-Chang Li,Stephen R Soffe
Alan Roberts
In young and developing amphibians and fish the spinal cord is functional but remarkably simple compared with the adult. Is the pattern of neurons and their connections common across at least these lower vertebrates? Does this basic pattern...