Gut instinct: Sex differences in the gut microbiome are associated with changes in adolescent nociception following maternal separation in rats [0.03%]
肠道直觉：与青春期大鼠母子分离后伤害感受变化有关的肠道微生物组性别差异
Sabrina Salberg,Matthew Macowan,Glenn R Yamakawa et al.
Sabrina Salberg et al.
Adolescent chronic pain is a growing public health epidemic. Our understanding of its etiology is limited; however, several factors can increase susceptibility, often developing in response to an acute pain trigger such as a surgical proced...
Lipid peroxidation and neuroinflammation: A possible link between maternal fructose intake and delay of acquisition of neonatal reflexes in Wistar female rats [0.03%]
脂质过氧化和神经炎症：可能导致Wistar雌性大鼠新生幼鼠反射获取延迟的母体果糖摄入的可能联系
Facundo H Prado Spalm,Marié L Cuervo Sánchez,Natalia E Furland et al.
Facundo H Prado Spalm et al.
Fructose is a common sweetener found in the daily diet supplemented to many processed and ultra-processed foods and beverages. Consumption of fructose-sweetened beverages has drastically increased in the last decades and is widely associate...
The effects of Wnt, BMP, and Notch signaling pathways on cell proliferation and neural differentiation in a song control nucleus (HVC) of Lonchura striata [0.03%]
Wnt、BMP和Notch信号通路对条纹文鸟歌曲控制核(HVC)细胞增殖及神经分化的影响
Jie Bing,Jing Sun,Rui Zhao et al.
Jie Bing et al.
There is obvious sexual dimorphism in the song control system of songbirds. In the higher vocal center (HVC), cell proliferation and neuronal differentiation contribute to the net addition of neurons. However, the mechanism underlying these...
Exploring behavioral phenotypes in a mouse model of fetal alcohol spectrum disorders [0.03%]
探索酒精谱系障碍的动物模型中的行为表型
Tammy R Chaudoin,Stephen J Bonasera,Anna Dunaevsky et al.
Tammy R Chaudoin et al.
Fetal alcohol spectrum disorders are one of the leading causes of developmental abnormalities worldwide. Maternal consumption of alcohol during pregnancy leads to a diverse range of cognitive and neurobehavioral deficits. Although moderate-...
Development of the hippocampal CA2 region and the emergence of social recognition [0.03%]
海马CA2区的发育与社交识别能力的产生
Emma J Diethorn,Elizabeth Gould
Emma J Diethorn
Social memories formed in early life, like those for family and unrelated peers, are known to contribute to healthy social interactions throughout life, although how the developing brain supports social memory remains relatively unexplored....
Characterization of neuropathology in ovine CLN5 and CLN6 neuronal ceroid lipofuscinoses (Batten disease) [0.03%]
溶酶体贮积病晚熟型婴儿ile-Batten病和Jansky-Bielschowsky病的神经病理学研究进展
Nadia L Mitchell,Katharina N Russell,Graham K Barrell et al.
Nadia L Mitchell et al.
Sheep with naturally occurring CLN5 and CLN6 forms of neuronal ceroid lipofuscinoses (Batten disease) share the key clinical features of the human disease and represent an ideal model system in which the clinical efficacy of gene therapies ...
Ten-m4 plays a unique role in the establishment of binocular visual circuits [0.03%]
Ten-m4在双眼视觉环路建立中发挥独特作用
Timothy R Young,Dylan Black,Hannan Mansuri et al.
Timothy R Young et al.
The patterning of binocular vision requires distinct molecular pathways for inputs arising from each side of the nervous system. Recent studies have demonstrated important roles for members of the Ten-m/Odz/teneurin family in the developmen...
Chong Wang,Jie Qin,Jianwei Jiao et al.
Chong Wang et al.
During brain development, the proliferation and differentiation of neural stem cells (NSCs) are precisely regulated. Defects in embryonic brain development can lead to serious developmental disorders. The cerebral cortex is the most evolved...
Claire M Kittock,Louis-Jan Pilaz
Claire M Kittock
In utero electroporation (IUE) is a technique developed in the early 2000s to transfect the neurons and neural progenitors of embryonic brains, thus enabling continued development in utero and subsequent analyses of neural development. Earl...
Loss of mitochondrial Chchd10 or Chchd2 in zebrafish leads to an ALS-like phenotype and Complex I deficiency independent of the mitochondrial integrated stress response [0.03%]
斑马鱼丧失线粒体Chchd10或Chchd2蛋白会导致渐冻症表型和复合物I缺乏，且与线粒体整合应激反应无关
Virginie Petel Légaré,Christian J Rampal,Tyler J N Gurberg et al.
Virginie Petel Légaré et al.
Mutations in CHCHD10 and CHCHD2, encoding two paralogous mitochondrial proteins, have been identified in cases of amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Parkinson's disease. Their role in disease is unclear, t...