Causal Relationship Between Matrix Metalloproteinase with Their Tissue Inhibitors and Human Immunodeficiency Virus Infection: A Two-Sample Bidirectional Mendelian Randomization Analysis [0.03%]
金属基质金属蛋白酶及其组织抑制剂与人类免疫缺陷病毒感染间的因果关系：两项样本双向孟德尔随机化分析
Chao Guo,Yushan Zhang,Xiujuan Li et al.
Chao Guo et al.
Studies have shown an association between matrix metalloproteinases (MMPs) along with tissue inhibitors of MMPs (TIMP) and human immunodeficiency virus (HIV) infection and CD4+ T cell count, a key clinical indicator for HIV progression, but...
Whole-Genome and RNA Sequencing Reveal Novel Insights into the Pathogenesis of Colorectal Cancer in Persons Living with HIV [0.03%]
全基因组和RNA测序揭示了人类免疫缺陷病毒携带者结直肠癌发病机制的新见解
Yuxue Gao,Pengxiang Yang,Yuanyue Guan et al.
Yuxue Gao et al.
In persons living with HIV (PWH), non-AIDS-related tumors, including colorectal cancer (CRC), have become major health concerns worldwide since the introduction of highly active antiretroviral therapy. To date, no study has addressed the un...
The HIV-1 Transmitted Drug Resistance in Newly Confirmed and ART-Naïve HIV-1-Infected MSM in Zhenjiang City, Jiangsu, China [0.03%]
中国江苏省镇江市新确认且未接受抗病毒治疗的MSM中HIV-1传播的耐药性调查研究报告
Li Shen,Yue Wu,Jin Liu et al.
Li Shen et al.
Estimating the prevalence and characterizing the HIV-1 transmitted drug resistance (TDR) are crucial for the prevention and control of HIV/AIDS. However, there are limited data currently on TDR among men who have sex with men (MSM) in Zhenj...
Acceptability of Hypothetical HIV Cure-Related Research Modalities: A Cross-Sectional Study of People Living with HIV in Soweto, South Africa [0.03%]
南非索韦托艾滋病病毒感染者对于假设性艾滋病治愈相关研究模式可接受性的横断面研究
Fatima Laher,Mbalenhle Sibiya,Naledi Mahlangu et al.
Fatima Laher et al.
Various modalities are being explored in HIV cure-related research, but little is documented on their acceptability in Africa, where HIV is most prevalent. To address this, we conducted a cross-sectional study in Soweto, South Africa, asses...
Temporal Analysis of HIV Burden in India and Its States Over Three Decades: Insights from the Global Burden of Disease Study 2019 [0.03%]
印度艾滋病负担的时空分布（1990-2019）：全球疾病负担研究新进展
Deepak Dhamnetiya,Tanishq Hitesh,Ravi Prakash Jha et al.
Deepak Dhamnetiya et al.
Acquired immunodeficiency syndrome (AIDS) is a group of disorders caused by the human immunodeficiency virus (HIV). Globally, 1.7 million people became newly infected with HIV in 2019. This study aims to assess trends in HIV burden in India...
Functional Reprogramming of Peripheral Eosinophils in Lentivirus-Infected Rhesus Macaques [0.03%]
模式灵长类动物 lentivirus 感染相关外周嗜酸粒细胞的再编程机制研究
Rhianna Jones,Ameera Afifi,R Keith Reeves et al.
Rhianna Jones et al.
As innate immune cells, granulocytic eosinophils form part of the first line of defense against pathogens. While recent studies indicate that granulocytes have additional functions including anti-inflammatory roles, tissue homeostasis maint...
Performance Characteristics of an HIV-1 Rapid Recency Assay Among Treatment-Naïve Individuals [0.03%]
HIV-1快速近期感染检测试剂在初治感染者中的性能特征分析
Xiaojuan Tan,Mervi Detorio,Vedapuri Shanmugam et al.
Xiaojuan Tan et al.
Asanté HIV-1 Rapid Recency Assay identifies HIV-1 recent infection based on antibody avidity among newly diagnosed individuals. We estimated the mean duration of recent infection (MDRI), false recency rate (FRR), the probability of being c...
Genetic Signatures of Immune Recovery in People Living with HIV on Long-Term Contemporary Antiretroviral Therapy [0.03%]
长期接受抗逆转录病毒治疗的HIV感染者的免疫恢复遗传特征
Damian Vangelov,Radoslava Emilova,Yana Todorova et al.
Damian Vangelov et al.
The advances in antiretroviral therapy (ART) bring forth an ever-growing percentage of aging people living with HIV (PLHIV) with successful immune restoration (SIR) but increased comorbidities and reduced quality of life. The current criter...
Adherence to Bone Mineral Density Screening Recommendations in Older Adults with HIV [0.03%]
HIV老年患者中骨密度筛查建议的依从性
Madison Martz,Nazar Akhverdyan,Melissa P Wilson et al.
Madison Martz et al.
HIV guidelines recommend bone mineral density (BMD) screening by dual-energy x-ray absorptiometry (DXA) for all postmenopausal women and all men ≥50 years, but uptake of these recommendations has been low. We conducted a retrospective cros...