Genomic Characterization of Two Novel HIV-1 CRF01_AE/CRF07_BC Unique Recombinant Forms in Shenzhen, China [0.03%]
中国深圳市两种新的HIV-1 CRF01_AE/CRF07_BC独特重组株的基因组特征分析
Dandan Lin,Bo Zhu,Shengya Liu et al.
Dandan Lin et al.
Recombination events are a key driver of human immunodeficiency virus type 1 (HIV-1) genetic diversity. In this study, HIV-1 samples were collected from two male patients in Shenzhen, China. Two novel recombinant forms (Ls6449 and Ls16801) ...
Post-Traumatic Stress Symptoms Related to the COVID-19 Pandemic in Persons Living and Aging with HIV [0.03%]
与COVID-19大流行相关的艾滋病毒携带者 PTSD症状
Sharon Walmsley,Majid Mabipoor,Alan Wai et al.
Sharon Walmsley et al.
The COVID-19 pandemic was an event involving an actual threat of death, serious injury, or harm to the integrity of self or others, which could have served as a precipitant for unmasking symptoms of post-traumatic stress disorder (PTSD). Pe...
Sequence Notes: Identification of a Novel HIV-1 Circulating Recombinant Form (CRF200_0755) in a Southern Border Region of Yunnan, China [0.03%]
序列分析发现中国云南省南部边境地区的HIV-1新型循环重组型(CRF200_0755)感染毒株
Min Chen,Huichao Chen,Yanling Ma et al.
Min Chen et al.
The long-term co-circulation of various HIV-1 subtypes and circulating recombinant forms (CRFs) in China has created an environment conducive to viral recombination. This study identified a novel HIV-1 CRF resulting from the recombination o...
Fluctuating Immune Reconstitution and Delayed HIV-1 DNA Decline in People Living with HIV with Low CD4 on Bictegravir-Based Therapy [0.03%]
基于比克替拉韦的治疗方案中CD4细胞计数较低的HIV感染者的免疫重建波动及HIV-1 DNA下降延迟现象
Jin Li,Minghua Zhou,Huizhuan Guo et al.
Jin Li et al.
This prospective cohort study compared the efficacy of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) and tenofovir/lamivudine/efavirenz (TLE) regimens in 88 treatment-naïve persons living with HIV. The BIC regimen achieved ...
Identification of a Complex HIV-1 Circulating Recombinant Form (CRF203_cpx) Originating from Three Main Circulating Recombinant Forms in China [0.03%]
在中国鉴定出一种复杂的HIV-1循环重组型病毒(CRF203_cpx)，源自三种主要的循环重组形式
Min Chen,Huichao Chen,Yanling Ma et al.
Min Chen et al.
Yunnan Province is recognized as a hotspot for the emergence of HIV-1 recombinant forms due to its complex epidemiological history. This study identified a novel circulating recombinant form (CRF) of HIV-1 in the region, designated as CRF20...
Near Full-Length Genome Characterization of a Novel Second-Generation HIV-1 CRF01_AE/CRF07_BC Recombinant Identified in an MSM Individual in Guizhou, China [0.03%]
中国贵州省 MSM 中发现的一种新型第二代 HIV-1 CRF01_AE/CRF07_BC 重组株的近全长基因组特征分析
Zhangwen Ge,Dan Liu,Hengzhi Zhong et al.
Zhangwen Ge et al.
The cocirculation of CRF01_AE and CRF07_BC among men who have sex with men (MSM) in China may facilitate the emergence of genetically complex HIV-1 recombinants. Here, we identified and characterized a novel second-generation HIV-1 CRF01_AE...
Evolving Indications and Diagnostic Spectrum of Bone Marrow Examination in People with HIV During the Antiretroviral Therapy Era: A 6-Year Retrospective Study [0.03%]
抗逆转录病毒治疗时代人免疫缺陷病毒感染者骨髓检查的适应证及诊断谱系的变迁：一项6年的回顾性研究
Jinglan Lai,Yahong Chen
Jinglan Lai
With the widespread use of antiretroviral therapy, the clinical spectrum among people with HIV has evolved significantly. This study aims to investigate the dynamic changes in the primary indications and final diagnostic spectrum of bone ma...
A Conserved Natural Killer Cell Transcriptional Fingerprint in Rhesus Macaque Models of Acute Viral Infections [0.03%]
恒河猴急性病毒感染的自然杀伤细胞转录指纹的保守性研究
Andrew Hudson,Kyle Kroll,Benjamin Bimber et al.
Andrew Hudson et al.
Natural killer (NK) cell activation and function are controlled by highly complex transcriptional programs. To leverage NK cells against human immunodeficiency virus and other diseases, a more complete understanding of signaling and metabol...
Perceived Ethical Risks of HIV Phylogenetic Research: Insights from Professional Stakeholders in Uganda [0.03%]
艾滋病病毒进化树研究中的伦理风险——乌干达专业人员的意见
Farirai Mutenherwa,Tom Lutalo,Ronald M Galiwango et al.
Farirai Mutenherwa et al.
HIV phylogenetics is a powerful tool for elucidating HIV transmission dynamics, but ethical concerns have been raised about its use. We conducted a cross-sectional online survey among HIV professional stakeholders in Uganda to explore their...
Genomic Characterization of Two Novel Human Immunodeficiency Virus-1 Recombinant Forms (CRF01_AE and B) in Men Who Have Sex with Men in Hebei, China [0.03%]
中国河北省 MSM 中两种新型人类免疫缺陷病毒 1 型重组型 (CRF01_AE 和 B) 的基因组特征分析
Yimin Cao,Shanshan Zang,Jian Du et al.
Yimin Cao et al.
Mutation and recombination are key mechanisms in the adaptation, spread, and genetic diversity of human immunodeficiency virus (HIV)-1. We identified two novel unique recombinant forms (URFs) from two persons living with HIV-1, both infecte...