Characterization of Two Novel HIV-1B/CRF01_AE/CRF07_BC Recombinant Forms Among Men Who Have Sex with Men in Hebei Province, China [0.03%]
中国河北省男性同性恋人群中两种新型HIV-1B/CRF01_AE/CRF07_BC重组株的特征分析
Feng Zhao,Ziting Liu,Jianru Jia et al.
Feng Zhao et al.
The frequent recombination between subtypes has driven significant HIV-1 genetic diversity in recent years, especially in some areas with co-circulation of multiple subtypes. In this study, we obtained nearly full-length genome sequences of...
The Immunogenicity of AAV-Encoded HIV-1 bNAbs in Rhesus Macaques Is Unaffected by a Short Course of the Immunomodulator CTLA4Ig [0.03%]
CTLA4Ig短期调节不影响血清型腺相关病毒介导的猴免疫缺陷病毒广谱中和抗体编码蛋白在恒河猴中的免疫原性
Patricia A Hahn,Siddhartha Shandilya,Lucas A B da Costa et al.
Patricia A Hahn et al.
Adeno-associated virus (AAV)-vectored delivery of HIV-1 broadly neutralizing antibodies (bNAbs) holds promise for achieving durable HIV-1 immunity in a practical and scalable way, yet AAV-encoded bNAbs often elicit antidrug antibody (ADA) r...
Circulating Short-Chain Fatty Acids: Association with Vaginal Microbiota, Genital Inflammation, and HIV Acquisition [0.03%]
循环短链脂肪酸与阴道微生态、生殖道炎症和HIV感染的关系
Rupak Shivakoti,Marothi Letsoalo,Lara Lewis et al.
Rupak Shivakoti et al.
Little is known about the relationships between circulating short-chain fatty acids (SCFAs) and genital microbiota, inflammation, and the risk for HIV infection in women. As circulating SCFAs are potentially modifiable, for example, through...
CD4 Discordance as a Predictor of Liver Fibrosis in People Coinfected with Human Immune Deficiency Virus/Hepatitis C Virus: A Cross-Sectional Study [0.03%]
CD4不一致作为人类免疫缺陷病毒/丙型肝炎病毒共感染人群肝纤维化的预测因素:一项横断面研究
Ahmed Cordie,Ahmed M Kamel,Rahma Mohamed et al.
Ahmed Cordie et al.
Liver fibrosis presents a unique diagnostic challenge in people coinfected with hepatitis C virus (HCV) and human immune deficiency virus (HIV). This study aimed to explore the association between CD4 discordance and liver fibrosis in that ...
Promoting Re-engagement in HIV Care after Emergency Department Visit by Leveraging Clinical Informatics at a Southern Academic Medical Center [0.03%]
利用临床信息学促进南部一家医学院附属医院急诊科访视后的HIV患者重新参与治疗护理
Naseem Alavian,Charles M Burns,Jeffrey D Jenks et al.
Naseem Alavian et al.
Retaining persons with HIV (PWH) in HIV care and ensuring access to antiretroviral therapy are crucial for reducing HIV transmission and enhancing health outcomes. HIV care engagement rates in the United States have plateaued over the last ...
Analysis of Factors Influencing Immunological Failure in Elderly People Living with HIV Undergoing Antiretroviral Therapy: A LASSO-Logistic Regression Approach [0.03%]
LASSO-Logistic回归分析艾滋病抗病毒治疗老年人免疫失败的影响因素
Ruilin Li,Yan Lu,Lianzhao Yang et al.
Ruilin Li et al.
This study aimed to identify key predictors of immunological failure in elderly patients with HIV receiving antiretroviral therapy (ART) through machine learning approaches. We conducted a retrospective analysis of 490 elderly patients with...
Adverse Lipid Profiles and Increased Cardiovascular Risks in People with HAM/TSP [0.03%]
与HAM/TSP相关的心血管疾病风险因素:血脂状况不容乐观
Ana Flávia Novaes,Qesya Rodrigues Ferreira,Jéssica Oliveira de Souza Nascimento et al.
Ana Flávia Novaes et al.
The human T-lymphotropic virus 1 (HTLV-1) affects millions globally, notably in Brazil. The classical neurological presentation of this infection is HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). There is limited infor...
Histoplasma capsulatum Not Detected in People with HIV and Systemic Symptoms in Port-au-Prince, Haiti [0.03%]
在海地太子港HIV患者中未发现荚膜组织胞浆菌
Kathryn M Dupnik,Nancy Dorvil,Maureen Ward et al.
Kathryn M Dupnik et al.
When local epidemiology of endemic fungal infections is poorly understood, it is difficult to determine the clinical impact of screening for these pathogens in people living with HIV. We found no Histoplasma urine antigen or serum antibody ...
Sequence Notes: Genomic Characterization of Two Novel HIV-1 Recombinant Forms (B/C) Among Men Who Have Sex with Men in Hebei, China [0.03%]
河北男性同性行为人群中的两种新型HIV-1重组株(B/C)的基因组特征分析
Xuanhe Zhao,Zhixia Chen,Jian Du et al.
Xuanhe Zhao et al.
The genetic diversity of HIV-1, driven by mutation and recombination, poses significant challenges to prevention and control efforts, particularly in regions like China where multiple subtypes and circulating recombinant forms co-circulate....
Comprehensive Cardiovascular Risk Profiling in People Living with HIV: Insights from the Japanese Adverse Drug Event Report Database [0.03%]
日本艾滋病患者心血管全面风险评估数据库报告分析启示
Shigeru Hasebe,Masayuki Tanaka,Shiori Iwane et al.
Shigeru Hasebe et al.
Antiretroviral therapy (ART) has dramatically improved outcomes for people living with HIV (PLWH), yet concerns about cardiovascular disease (CVD) remain, especially in aging populations. In this study, we aimed to evaluate the association ...