Comparison of Plasma, Dried Blood Spots, and Peripheral Blood Mononuclear Cells as Biosamples for HIV-1 Genotypic Drug Resistance in a Tertiary Care Center [0.03%]
特护中心HIV-1基因型耐药性血浆、干血点和外周血单个核细胞生物样本的比较研究
Priyanka Sabu,Diviya Alex,Veena Vadhini Ramalingam et al.
Priyanka Sabu et al.
The collection, storage, and transport of plasma, the ideal specimen for HIV-1 genotyping, is plagued by technical difficulties in resource-limited settings. We aimed to compare corresponding bio-samples for HIV-1 genotypic drug resistance ...
Frequency of CCR5-Δ32, CCR2-64I, and SDF1-3'A Mutations in People with HIV Diagnoses and HIV Negative Participant in Khuzestan Province, Iran [0.03%]
伊朗胡泽斯坦省HIV感染者和HIV阴性参与者的CCR5-Δ32、CCR2-64I和SDF1-3'A突变频率调查研究
Mina Bavi,Shahram Jalilian,Mehdi Bijanzadeh et al.
Mina Bavi et al.
Human immunodeficiency virus type 1 (HIV-1) binds to CD4 receptors. Chemokine receptors such as C-C chemokine receptor type 5 (CCR5), C-C chemokine receptor type 2 (CCR2), and stromal-derived factor (SDF1) are involved in HIV cell entry, an...
HCV Genotype Distribution and Molecular Characteristics of HCV Core Domain I in Persons Living with HIV and HCV from Yunnan Province, China [0.03%]
中国云南省艾滋病和丙肝病毒合并感染人群的丙肝病毒基因型分布及其核心蛋白I区分子特征
Yantao Zhu,Junyi Liu,Lijuan Kang et al.
Yantao Zhu et al.
Yunnan Province, a critical southwestern Chinese border region and gateway to Southeast Asia, faces a complex human immunodeficiency virus (HIV)/hepatitis C virus (HCV) co-infection epidemic. Molecular data on HCV Core domain I in persons l...
Psychological Impact of Analytical Treatment Interruption on Young Women Enrolled in an HIV Cure-Related Clinical Trial in Durban, South Africa [0.03%]
在南非德班进行HIV治愈相关临床试验的年轻女性中断分析治疗的心理影响
Ali Ahmed,Krista L Dong,Maryam Hussain et al.
Ali Ahmed et al.
Analytical treatment interruption (ATI) is a planned and monitored pause of ART used in HIV-related studies that enables measurement of viral rebound kinetics and immune responses, yet it may pose psychological risks to participants. Eviden...
Exploring Potential Associations Between HIV Acquisition and Biological Aging: Insights from a Bidirectional Mendelian Randomization Study [0.03%]
基于双向孟德尔随机化研究探讨HIV感染与生物衰老之间的潜在关联
Haili Wang,Hong Fan,Chengnan Guo et al.
Haili Wang et al.
Accumulating evidence indicates that HIV acquisition may be associated with premature aging. However, the causal relationship and the direction of the effect between HIV acquisition and aging remain controversial. In the present study, we a...
Bictegravir/Emtricitabine/Tenofovir Alafenamide in HIV-1-Infected Pregnant Women: Real-Life Use [0.03%]
HIV-1感染者孕妇中的比克替拉韦/恩曲他滨/特鲁瓦达艾芬钠:实际应用情况
Antoine Bachelard,Zélie Julia,Florence Damond et al.
Antoine Bachelard et al.
Bictegravir/Emtricitabine/Tenofovir alafenamide (BIC/FTC/TAF) is a convenient, well-tolerated, once-daily, and single-tablet regimen. There are few data on its use during pregnancy. The primary objective was to evaluate the efficacy of BIC/...
HTLV-1 Secreted Proteins Induce Axonal Degeneration Through Kinase and Phosphatase Activity Dysregulation [0.03%]
通过激酶和磷酸酶活性失调诱导的人类T细胞白血病病毒-1分泌蛋白诱导轴突退变
Sebastian Quintremil,María Antonieta Valenzuela,Matías Rivera et al.
Sebastian Quintremil et al.
HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) pathology has been associated with Tax protein secreted from HTLV-1 infected CD4+-T-lymphocytes, which interacts with soluble SEMA-4D (Semaphorin 4D) inducing growth cone c...
Effectiveness of Short Message Service Reminders on Timely Pick-up of Antiretroviral Therapy Among Consenting Persons with HIV in Zambézia Province, Mozambique [0.03%]
莫桑比克赞贝西亚省艾滋病毒知情同意感染者抗逆转录病毒治疗及时领取短信提醒有效性的研究
Erin Graves,Caroline De Schacht,Wu Gong et al.
Erin Graves et al.
A short message service (SMS) intervention was implemented in July 2016 at eight health facilities (HFs) within Zambézia Province, Mozambique. We assessed effectiveness by comparing antiretroviral therapy (ART) pick-up rates among persons ...
Late HIV Diagnosis in Thrace, Turkey: A Six-Year Experience from a Border Region [0.03%]
土耳其色雷斯边境地区6年的HIV晚期诊断经验
Merve Aytekin,Habibe Tülin Elmaslar Mert
Merve Aytekin
Despite advances in diagnosis and treatment, human immunodeficiency virus (HIV) infection still continues to be a globally important public health problem. While early diagnosis facilitates the control of the disease, late diagnosis can aff...
Identification of an Emerging HIV-1B/C Circulating Recombinant Form (CRF176_BC) in Heterosexual Populations in Yunnan Province, China [0.03%]
在中国云南省异性人群中新兴的HIV-1重组型CRF176_BC的识别
Min Chen,Yanling Ma,Huichao Chen et al.
Min Chen et al.
The current HIV-1 epidemic in China is characterized by the co-circulation of multiple subtypes and recombinant forms. A novel circulating recombinant form of HIV-1 (CRF176_BC) has been identified in Yunnan Province, China. Near-full-length...