Genevieve M Ames,Joel B Bennett
Genevieve M Ames
The workplace offers advantages as a setting for interventions that result in primary prevention of alcohol abuse. Such programs have the potential to reach broad audiences and populations that would otherwise not receive prevention program...
Abigail A Fagan,J David Hawkins,Richard F Catalano
Abigail A Fagan
Community-based efforts offer broad potential for achieving population-level reductions in alcohol misuse among youth and young adults. A common feature of successful community strategies is reliance on local coalitions to select and fully ...
Traci L Toomey,Kathleen M Lenk
Traci L Toomey
Alcohol use and related problems can be influenced by a wide variety of prevention interventions, including efforts that focus on changing the community alcohol environment-for example, by reducing underage access to alcohol, decreasing alc...
Melissa H Stigler,Emily Neusel,Cheryl L Perry
Melissa H Stigler
Schools are an important setting for interventions aimed at preventing alcohol use and abuse among adolescents. A range of school-based interventions have been developed to prevent or delay the onset of alcohol use, most of which are target...
Defining risk drinking [0.03%]
界定危险饮酒行为
Deborah A Dawson
Deborah A Dawson
Many efforts to prevent alcohol-related harm are aimed at reducing risk drinking. This article outlines the many conceptual and methodological challenges to defining risk drinking. It summarizes recent evidence regarding associations of var...
Jürgen Rehm
Jürgen Rehm
Alcohol consumption, particularly heavier drinking, is an important risk factor for many health problems and, thus, is a major contributor to the global burden of disease. In fact, alcohol is a necessary underlying cause for more than 30 co...
How adaptation of the brain to alcohol leads to dependence: a pharmacological perspective [0.03%]
脑对酒精的适应如何导致依赖：药理学观点
Peter Clapp,Sanjiv V Bhave,Paula L Hoffman
Peter Clapp
The development of alcohol dependence is posited to involve numerous changes in brain chemistry (i.e., neurotransmission) that lead to physiological signs of withdrawal upon abstinence from alcohol as well as promote vulnerability to relaps...
Natalie M Zahr,Edith V Sullivan
Natalie M Zahr
Human studies are necessary to identify and classify the brain systems predisposing individuals to develop alcohol use disorders and those modified by alcohol, while animal models of alcoholism are essential for a mechanistic understanding ...
Nicholas W Gilpin,George F Koob
Nicholas W Gilpin
Alcoholism is a debilitating disorder for the individual and very costly for society. A major goal of alcohol research is to understand the neural underpinnings associated with the transition from alcohol use to alcohol dependence. Positive...