The Effects of a Modified Mediterranean Diet on Gut Microbiota and Chemotherapy Side Effects in Patients With Metastatic Colorectal Cancer Undergoing First-Line Chemotherapy With or Without Either Antiepidermal Growth Factor Receptor or Antivascular Endothelial Growth Factor Agent: Protocol for a Randomized Pilot Study in Italy [0.03%]
改良的地中海饮食对转移性结直肠癌患者肠道微生物群和化疗副作用的影响：一项关于意大利一线化疗患者的随机试点研究方案
Salvatore Artale,Francesca Filiali,Elena Beretta et al.
Salvatore Artale et al.
Background: The gut microbiota is attracting increasing interest as a factor possibly impacting colorectal cancer risk, therapy toxicity, and, as a consequence, patient's quality of life. It has been observed that microbi...
Supporting Oral and Long-Acting HIV Preexposure Prophylaxis Decision-Making Among Pregnant Women (MyChoice Intervention): Protocol for 2 Pilot Randomized Controlled Trials [0.03%]
关于孕期妇女支持口服和长效暴露前预防决策的方案（MyChoice干预）：2项初步随机对照试验的方案
Friday Saidi,Symone Welch,Twambilile Phanga et al.
Friday Saidi et al.
Background: HIV preexposure prophylaxis (PrEP) has potential for preventing HIV during the perinatal period, but few strategies promote person-centered shared decision-making (SDM) about PrEP use in these contexts. The My...
A Novel Digital Platform to Support Child and Family Mental Health in Australia (Child and Family eHub): Protocol for a Mixed Methods Evaluation [0.03%]
支持澳大利亚儿童及家庭精神健康的新颖数字平台（儿童及家庭电子中心）：混合研究评价方案
Suzy Honisett,Raghu Lingam,Valsamma Eapen et al.
Suzy Honisett et al.
Background: Child mental health disorders are a significant Australian public health issue with high prevalence rates compounded by inequitably higher rates for those living in families with lower income, lower levels of ...
Evaluating the Impact of Telehealth Exercise Prehabilitation on Cardiometabolic Health in Bariatric Surgery Candidates: Protocol for the BARI-Prehab Randomized Controlled Trial [0.03%]
远程健康锻炼预康复对代谢手术候选者的心脏代谢健康的影响评估：BARI-Prehab随机对照试验方案
Belinda Jayne Durey,Alison M Coates,Kade Davison et al.
Belinda Jayne Durey et al.
Background: Obesity affects over one billion people globally and is a leading contributor to chronic disease. For those with clinically severe obesity, metabolic and bariatric surgery (MBS) is the most effective intervent...
Methodological Approach for Dengue Viral Load Quantification in Wastewater: Protocol for a Systematic Review and Meta-Analysis [0.03%]
污水登革病毒载量测定方法学：系统评价和元分析方案
Nurul Amalina Khairul Hasni,Sakshaleni Rajendiran,Nurul Athirah Naserrudin et al.
Nurul Amalina Khairul Hasni et al.
Background: In recent years, the rapid emergence and global spread of dengue has become a public health burden. Clinical surveillance alone has limited capacity, with delayed detection of upcoming outbreaks. Hence, the po...
Feasibility of mHealth Strategies to Promote Use of Wrist-Worn Alcohol Biosensors Among Young Adults With HIV: Protocol for the Engage Microrandomized Trial [0.03%]
面向HIV阳性年轻人促进使用手腕型酒精生物传感器的移动健康策略可行性研究：Engage微型随机试验方案
Stephanie M Carpenter,Stuart Case,Mia Liza A Lustria et al.
Stephanie M Carpenter et al.
Background: Alcohol use among young adults with HIV is disproportionately high compared to other age groups with HIV, despite its negative health-related consequences. However, alcohol use interventions tailored to the in...
Effect of Obesity on Perioperative Outcomes Following Lung Cancer Surgery: Protocol for a Meta-Analysis and Systematic Review [0.03%]
肥胖对肺癌手术围术期结局影响的meta分析和系统综述的研究方案
Qiuxiang Wang,Zhishu Li,Xihuan Wang et al.
Qiuxiang Wang et al.
Background: Surgical resection is the primary curative treatment for early-stage lung cancer-the leading global cause of cancer mortality, responsible for nearly 1 in 5 cancer deaths in 2022. Obesity is a global health co...
Culturally Tailored Tele-Mental Health Care Linkage for Indigenous Populations: Protocol for a Mixed Methods Pilot Study [0.03%]
针对原住民人群的文化适应性远程心理健康服务链接：混合研究法试点研究方案
Ariel M S Richer,Ariel L Roddy,Sutton King et al.
Ariel M S Richer et al.
Background: Urban Indigenous populations face disproportionate mental health challenges, including high rates of posttraumatic stress disorder, depression, and substance use disorders, yet they have limited access to heal...
Digital Health Tool for Preventing Blindness From Diabetic Retinopathy: Protocol for a Qualitative Study [0.03%]
糖尿病视网膜病变数字健康工具的预防盲文协议：定性研究方案
Akua Frimpong,Alvaro Granados,Thomas Chang et al.
Akua Frimpong et al.
Background: Diabetic retinopathy (DR), a leading cause of preventable blindness among working-age adults, leads to worse health outcomes among Black, Latine, and individuals with lower income in comparison to other ethnic...
Psychological Factors Influencing Pain Perception and Experience in Women Undergoing Mammography: Protocol for a Systematic Review [0.03%]
影响女性乳腺X线摄影疼痛感知和体验的心理因素：系统评价方案
Irene Neophytou,George Charalambous,Eleni Jelastopulu
Irene Neophytou
Background: Breast cancer is the most frequently diagnosed cancer among women worldwide and a leading cause of cancer-related mortality. Mammographic screening significantly improves the early detection and survival rates...