Long-Term Outcome of Eltrombopag With First-Line Immunosuppressive Therapy for Newly Diagnosed Severe Aplastic Anemia [0.03%]
艾曲波帕联合一线免疫抑制剂治疗新诊断的重度再生障碍性贫血长期疗效分析
Hirofumi Yokota,Kotaro Miyao,Masashi Sawa et al.
Hirofumi Yokota et al.
Background: To investigate whether the addition of eltrombopag (EPAG) to rabbit anti-thymocyte globulin (ATG)-based immunosuppressive therapy (IST) for newly diagnosed severe aplastic anemia (SAA) improves outcomes and af...
Maria Pantelidou,Eleni Dimitriou,Konstantinos Gkontopoulos et al.
Maria Pantelidou et al.
Multiple myeloma is a plasma cell dyscrasia with an age-standardized incidence of 3 - 4 per 100,000 in the Caucasian population. It is the second most common hematological malignancy after non-Hodgkin lymphoma, representing 1% of all cancer...
Case Reports
Journal of hematology. 2024 Aug;13(4):164-167. DOI:10.14740/jh1267 2024
A Case of Autoimmune Myelofibrosis Associated With Autoimmune Hepatitis [0.03%]
一例与自身免疫性肝炎相关的自身免疫性骨髓纤维化病例
Hailey Tyndall,Lawrence Worobetz,Matthew Nicholson
Hailey Tyndall
Autoimmune myelofibrosis (AIMF) is a distinct, underrecognized, and rare cause of bone marrow fibrosis. It carries a favorable outcome and responds well to immunosuppression. Systemic lupus erythematosus is the most common association with ...
Case Reports
Journal of hematology. 2024 Aug;13(4):158-163. DOI:10.14740/jh1297 2024
Acquired Aplastic Anemia Therapies: Immunosuppressive Therapy Versus Alternative Donor Hematopoietic Cell Transplantation [0.03%]
获得性再生障碍性贫血的治疗：免疫抑制疗法与替代供者造血细胞移植的区别
Baldeep Wirk
Baldeep Wirk
Immunosuppressive therapy for acquired severe aplastic anemia improves pancytopenia but has a significant risk of relapse (40%) and clonal evolution to myeloid neoplasms (15%), especially in patients older than 40. Yet, current guidelines f...
Sickle Cell Screening in Adults: A Current Review of Point-of-Care Testing [0.03%]
成人镰状细胞筛查：即时检验的最新综述
Sebastian R Mendez-Marti,Chad Zik,Sheinei Alan et al.
Sebastian R Mendez-Marti et al.
In adults, the sickle cell solubility test (SCST) is the most common screening test to determine the presence of hemoglobin S (HbS) within a blood sample. The assay is inexpensive, rapid, highly sensitive and specific. However, the SCST can...
Frameshift Mutations in Leukemia-Associated Genes Correlate With Superior Outcomes in Patients Undergoing Allogeneic Stem Cell Transplant for De Novo Acute Myeloid Leukemia [0.03%]
急性髓系白血病患者进行同种异体干细胞移植后，与较佳预后相关的 leukemia-associated 基因移位突变研究
Emma Cammann,Sindha Madhav,Lloyd Hutchinson et al.
Emma Cammann et al.
Background: Allogeneic stem cell transplant (allo-SCT) is a mainstay of treatment for acute myeloid leukemia (AML). Its success depends largely on response of donor T lymphocytes against leukemia cells, known as graft-vs-...
Venous Thromboembolism Following COVID-19 Vaccination in Patients With Hereditary Protein S Deficiency [0.03%]
遗传性蛋白S缺乏患者接种新冠疫苗后发生静脉血栓栓塞事件
Molly Rayner,Kelsey Brose
Molly Rayner
Hereditary protein S (PS) deficiency is a rare condition associated with increased risk of venous thromboembolism (VTE). In 2020, the coronavirus disease 2019 (COVID-19) pandemic prompted development of vaccinations to protect against the v...
Case Reports
Journal of hematology. 2024 Jun;13(3):125-127. DOI:10.14740/jh1278 2024
A Hemoglobinopathy That Produces an Array of Different Hemoglobin A1c Values [0.03%]
一种可产生多种不同糖化血红蛋白A1c值的异常血红蛋白病
Maximo J Marin,Bremansu Osa-Andrews,Patrick A Maher et al.
Maximo J Marin et al.
Hemoglobin A1c (HbA1c) refers to non-enzymatically glycated hemoglobin and reflects the patient's glycemic status over approximately 3 months. An elevated HbA1c over 6.5% National Glycohemoglobin Standardization Program (NGSP) (48 mmol/mol ...
Case Reports
Journal of hematology. 2024 Jun;13(3):99-103. DOI:10.14740/jh1268 2024
Non-Secretory Multiple Myeloma Associated With High-Risk Phenotype and Complex Cytogenetics Including t(8;22) [0.03%]
伴有高危表型和包括t(8;22)的复杂细胞遗传学的无分泌多发性骨髓瘤
Rahim A Jiwani,Joseph R Liput,Attah Abraham et al.
Rahim A Jiwani et al.
Multiple myeloma (MM) is a plasma cell dyscrasia which is typically characterized by identifiable paraprotein in the blood or urine. However, the minority of patients in whom paraprotein cannot be identified are designated non-secretory MM ...
Case Reports
Journal of hematology. 2024 Jun;13(3):94-98. DOI:10.14740/jh1248 2024
Recurrent Infection in a Young Female Patient Recently Diagnosed With Primary Evans Syndrome Without Neutropenia [0.03%]
一名近期确诊为原发Evans综合征(无中性粒细胞减少)的年轻女性患者反复感染
Jennie An,Preye Amaruntowa,Waleed Ahmed et al.
Jennie An et al.
Evans syndrome (ES) is a rare autoimmune condition of unknown etiology that occurs in a small subset of patients diagnosed, either sequentially or concomitantly, with immune thrombocytopenia (ITP) or warm autoimmune hemolytic anemia (AIHA)....
Case Reports
Journal of hematology. 2024 Jun;13(3):121-124. DOI:10.14740/jh1265 2024