Methionine Synthase Reductase A66G Variant in Pediatric Acute Lymphoblastic Leukemia Patients [0.03%]
儿科急性淋巴细胞白血病患者中的蛋氨酸合酶还原酶A66G变异型
Elrashed B Yasin,Haitham M H Qutob,Raed Alserihi
Elrashed B Yasin
Background: Methionine synthase reductase, which is encoded by the methionine synthase reductase (MTRR) gene, plays a crucial role in the methylation reactions and the production of DNA and its epigenetic processes. There...
Scedosporium Brain Abscess: A Rare and Fatal Drawback of Bruton Tyrosine Kinase Inhibitor Therapy [0.03%]
布鲁顿酪氨酸激酶抑制剂治疗罕见而致命的副作用：scedosporium脑脓肿
Matteo Dalmazzo,Melissa Padrini,Sofia Camerlo et al.
Matteo Dalmazzo et al.
The patient described in this case report was admitted to the San Luigi Hospital in Turin for confusion, drowsiness, and buccal and eye deviation. An acute neurological disease was suspected. He was affected by chronic lymphocytic leukemia ...
Case Reports
Journal of hematology. 2024 Oct;13(5):224-228. DOI:10.14740/jh1263 2024
Primary Refractory Discordant Diffuse Large B-Cell and Classical Hodgkin Lymphoma [0.03%]
主要难治性弥漫性大B细胞淋巴瘤与经典型霍奇金淋巴瘤并发病例
Yuxin Bai,Samantha Bolger,Sahar Khan et al.
Yuxin Bai et al.
Discordant lymphomas are defined as two or more distinct pathological lymphomas occurring in the same patient. Due to the rarity of discordant lymphomas, which is due in large part to the difficulty in establishing the diagnosis, the litera...
Case Reports
Journal of hematology. 2024 Oct;13(5):238-244. DOI:10.14740/jh1303 2024
Controversies in the Management of Ischemic Cerebrovascular Accidents in Patients With Non-Promyelocytic Acute Myeloid Leukemia [0.03%]
非促粒细胞急性髓系白血病患者缺血性脑血管意外管理中的争议
Rodrick Babakhanlou,Ravinathan Krishnadasan
Rodrick Babakhanlou
Ferritin and Iron Levels Inversely Associated With Lymphoma Risk: A Mendelian Randomization Study [0.03%]
铁蛋白和铁水平与淋巴瘤风险呈负相关：一项孟德尔随机化研究
Boyuan Wu
Boyuan Wu
Background: Current knowledge on iron's role in lymphoma development is very limited, with studies yielding inconsistent findings. To address this gap, we conducted a rigorous two-sample mendelian randomization study, aim...
Transformation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma to Histiocytic/Dendritic Cell Sarcoma [0.03%]
慢性淋巴细胞白血病/小淋巴细胞淋巴瘤向组织细胞/树突状细胞肉瘤转化
Jennifer Cai,David Fernandez-Hazoury,Gene Yoshikawa et al.
Jennifer Cai et al.
Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) transforming into a more aggressive lymphoma (i.e., Richter syndrome) is well documented in the literature. In recent years, transdifferentiation of CLL/SLL to histiocytic/de...
Case Reports
Journal of hematology. 2024 Oct;13(5):216-223. DOI:10.14740/jh1310 2024
Allogeneic Hematopoietic Stem Cell Transplantation After Solid Organ Transplantation in Patients With Hematologic Malignancies Managed With Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis [0.03%]
接受环磷酰胺为基础的移植物抗宿主病预防治疗后器官移植患者的同种异体造血干细胞移植
Charley Jang,Jingmei Hsu
Charley Jang
Patients who receive solid organ transplants often require lifelong immunosuppression, which increases their risk for hematologic disorders. Allogeneic hematopoietic stem cell transplantation (HSCT) offers a potential curative treatment opt...
Case Reports
Journal of hematology. 2024 Oct;13(5):250-258. DOI:10.14740/jh1327 2024
Utility of p53 Immunohistochemical Staining for Risk Stratification of Mantle Cell Lymphoma [0.03%]
p53免疫组化在套细胞淋巴瘤预后分层中的价值分析
Ibrahim Elsharawi,Sorin Selegean,Michael Carter
Ibrahim Elsharawi
Background: Inactivating TP53 mutations in mantle cell lymphoma (MCL) are associated with poor prognosis. While next-generation sequencing (NGS) is the gold standard for assessing TP53, p53 immunohistochemistry (IHC) is a...
The Influence of Circulating Exosomes Derived From Younger and Older Donors on Hypoxia-Inducible Factor 1 Alpha Gene Expression and P21 Protein in Cord Blood Hematopoietic Stem Cells [0.03%]
来自年轻和年老供者的循环外泌体对脐血造血干细胞中缺氧诱导因子1α基因表达及P21蛋白的影响
Zahra Rasti,Reza Afrisham,Elahe Bahrami Vahdat et al.
Zahra Rasti et al.
Background: Exosomes are a group of extracellular vesicles that are influential in intercellular signaling and can affect aging. Hypoxia-inducible factor 1α (HIF-1α) is the principal mediator in response to hypoxia and ...
Systemic Epstein-Barr Virus-Positive T-Cell Lymphoma of Childhood Associated With t(1;22)(p22;q11.2) Mutation [0.03%]
与t(1;22)(p22;q11.2)易位有关的儿童EB病毒阳性T细胞淋巴瘤
Lane Lerner,Sushanth Sreenivasan,Chelsea Peterson et al.
Lane Lerner et al.
Systemic Epstein-Barr virus-positive (EBV+) T-cell lymphoma (TCL) of childhood is an uncommon TCL that occurs secondary to an acute or chronic EBV infection. The disorder is characterized by the monoclonal expansion of EBV+ T cells driven b...
Case Reports
Journal of hematology. 2024 Oct;13(5):229-237. DOI:10.14740/jh1284 2024