Clinical Impact of Percentage of Natural Killer Cells and Natural Killer-Like T Cell Population in Acute Myeloid Leukemia [0.03%]
自然杀伤细胞和自然杀伤T细胞比值在急性髓系白血病中的临床影响研究
Esraa Jamal,Emad Azmy,Mohamed Ayed et al.
Esraa Jamal et al.
Background: Natural killer (NK) function defects have been seen in many hematological malignancies, including acute myeloid leukemia (AML). AML is associated with deficient human leukocyte antigen (HLA) expression on leuk...
Outcomes of Reduced Frequency Dosing of Ibrutinib in Chronic Lymphocytic Leukemia Patients Following Complete or Partial Remission: A Pilot Study [0.03%]
伊布替尼在慢性淋巴细胞白血病患者完全或部分缓解后减少用药频率的结果：初步研究
William Alexander,Sarah Davis,Raj Ramakrishna et al.
William Alexander et al.
Background: Ibrutinib is a Bruton's tyrosine kinase inhibitor that has shown to be a superior choice in the treatment of chronic lymphocytic leukemia (CLL) and a simple, oral alternative to other chemoimmunotherapies. The...
Impact of Opioid Use in Hematological Malignancies: Clinical, Immunological and Concomitant Aspects [0.03%]
在血液系统恶性肿瘤中使用阿片的影响：临床、免疫及并发症状方面
Polina Tregubenko,Valeriy Zvonarev
Polina Tregubenko
Opioid agents play a unique role in pain and symptom management for cancer patients. Research shows that opiate use, especially when associated with underlying cancer, has significant effects on hematological parameters. These changes may l...
Diagnostic Dilemma: An Unusual Case of Angioimmunoblastic T-Cell Lymphoma Manifesting as Bone Marrow Non-Caseating Granuloma [0.03%]
诊断难题：一种罕见的血管免疫母T细胞淋巴瘤表现为骨髓非干酪样肉芽肿病例
Vineel Bhatlapenumarthi,Anannya Patwari,Sheila Karina Pascual
Vineel Bhatlapenumarthi
We present here a rare and unusual presentation of angioimmunoblastic T-cell lymphoma with non-necrotizing granuloma of bone marrow. We did not find any case reports of such case in our literature search. A 77-year-old man presented with sh...
Case Reports
Journal of hematology. 2020 Apr;9(1-2):37-40. DOI:10.14740/jh607 2020
Lenalidomide Plus Decitabine Treatment in a Myelodysplastic Syndrome Patient With Deletion 5q and Excess Blasts [0.03%]
来那度胺联合地西他滨治疗5q缺失伴过度增生的骨髓增生异常综合征患者
Istemi Serin,Rafet Eren,Mehmet Hilmi Dogu
Istemi Serin
This is the first case of decitabine plus lenalidomide treatment for a myelodysplastic syndrome (MDS) patient with 5q deletion (del(5q)) and elevated number of blasts. Upon bone marrow aspiration and biopsy with conventional cytogenetical s...
Case Reports
Journal of hematology. 2020 Apr;9(1-2):33-36. DOI:10.14740/jh618 2020
Prolonged Remission by Pembrolizumab and Brentuximab-Vedotin Combination Therapy in Heavily-Pretreated Relapsed/Refractory Hodgkin's Lymphoma [0.03%]
帕博利珠单抗联合贝林妥莫双药方案治疗复发/难治性霍奇金淋巴瘤的长期疗效
Tsung-Ying Yu,Ming-Shen Dai
Tsung-Ying Yu
Hodgkin's lymphoma (HL) is usually sensitive and curative to multi-agent chemotherapy, but may become refractory disease in a subset of relapsed patients. Recent novel agents, brentuximab-vedotin (BV) and immune checkpoint inhibitors have s...
Case Reports
Journal of hematology. 2020 Apr;9(1-2):30-32. DOI:10.14740/jh596 2020
Emergence of BCR-ABL1 Chronic Myeloid Leukemia in a JAK2-V617F Polycythemia Vera [0.03%]
一名真性红细胞增多症患者出现BCR-ABL1慢性粒细胞白血病
Mariana Lorenzo,Sofia Grille,Mariana Stevenazzi
Mariana Lorenzo
Emergence of a new chronic myeloid neoplasm in the setting of a previous one, or their concomitant appearance seems to be a rare event, but plenty of cases have been reported. We describe the case of a patient with JAK2-V617F polycythemia v...
Case Reports
Journal of hematology. 2020 Apr;9(1-2):23-29. DOI:10.14740/jh591 2020
Spontaneous Remission in a Patient With Acute Myeloid Leukemia Leading to Undetectable Minimal Residual Disease [0.03%]
一例急性髓系白血病患者病情自发缓解使最小残留病变无法检测到
Daniel Helbig,Andres E Quesada,Wenbin Xiao et al.
Daniel Helbig et al.
Although rare, spontaneous remission (SR) of acute myeloid leukemia (AML) has been reported in the literature, the underlying mechanisms driving remission remain unknown. However, it is most commonly associated with a preceding severe infec...
Case Reports
Journal of hematology. 2020 Apr;9(1-2):18-22. DOI:10.14740/jh606 2020
Novel Translocation in Acute Myeloid Leukemia: Case Report and Review of Risk-Stratification and Induction Chemotherapy in Patients With Acute Myeloid Leukemia [0.03%]
急性髓系白血病新的易位类型：病例报告及急性髓系白血病患者危险分层和诱导化疗的综述
George M Jeha,Tiffany Wesley,Vince D Cataldo
George M Jeha
Identification of chromosomal abnormalities in patients with acute myeloid leukemia (AML) has contributed substantially to our current understanding of the molecular pathogenesis underlying leukemogenesis, and risk-stratification based on m...
Case Reports
Journal of hematology. 2020 Apr;9(1-2):13-17. DOI:10.14740/jh605 2020
Shunji Suzuki,Takafumi Kimura,Sumiko Hara et al.
Shunji Suzuki et al.
Background: Umbilical cord blood (UCB) has become an established alternative source of hematopoietic stem cells with marrow and postmobilization peripheral blood. The presence of a large amount of clots may lead to the de...