Acute Promyelocytic Leukemia Treatment Masking Hepatic Tuberculosis: A Management Dilemma [0.03%]
急性早幼粒细胞白血病掩盖肝结核：治疗困境
Kimberly Boldig,Amy Kiamos,Trevanne Matthews-Hew et al.
Kimberly Boldig et al.
Acute promyelocytic leukemia is a form of acute myeloid leukemia (AML) that is characterized by presence of a promyelocytic leukemia-retinoic acid receptor alpha fusion. In most patients, this fusion is detected on conventional karyotype as...
Case Reports
Journal of hematology. 2023 Apr;12(2):100-104. DOI:10.14740/jh1109 2023
Treatment and Response Evaluation Challenges in a Pregnant Woman With B-Cell Lymphoblastic Leukemia and Li-Fraumeni Syndrome [0.03%]
妊娠合并B细胞急性淋巴细胞白血病和利弗莫尔综合征的治疗及疗效评价挑战
Bjarte Skoe Erikstein,Aymen Bushra Ahmed,Rakel Brendsdal Forthun et al.
Bjarte Skoe Erikstein et al.
Li-Fraumeni syndrome (LFS) is a cancer predisposing syndrome caused by pathogenic germline TP53 gene mutations with important therapeutic and prognostic implications for many types of cancer. A small proportion of LFS patients develop B-cel...
Case Reports
Journal of hematology. 2023 Apr;12(2):92-99. DOI:10.14740/jh1107 2023
Sasmith R Menakuru,Janet Roepke,Salahuddin Siddiqui
Sasmith R Menakuru
B-cell prolymphocytic leukemia (B-PLL) is a rare B-cell neoplasm that typically presents with splenomegaly, a rising white blood cell count, and may or may not have B symptoms. The diagnosis usually requires a bone marrow biopsy and aspirat...
Case Reports
Journal of hematology. 2023 Apr;12(2):82-86. DOI:10.14740/jh1096 2023
Binoy Yohannan,Adan Rios
Binoy Yohannan
Primary lymphoma of the bone (PLB) is a rare lymphoproliferative neoplasm that can present either as solitary or multiple bone lesions. We report four patients with PLB who were successfully treated with R-CHOP (rituximab, cyclophosphamide,...
Case Reports
Journal of hematology. 2023 Apr;12(2):75-81. DOI:10.14740/jh1087 2023
Clofarabine in Pediatric Acute Relapsed or Refractory Leukemia: Where Do We Stand on the Bridge to Hematopoietic Stem Cell Transplantation? [0.03%]
克罗拉滨治疗儿科急性复发或难治性白血病：我们在造血干细胞移植之桥的何处？
Sarah Ramiz,Osama Elhaj,Khawar Siddiqui et al.
Sarah Ramiz et al.
Background: Despite pronounced improvement in overall survival (OS) in pediatric leukemia, a proportion of patients continue to suffer from lack of response or relapse, and the management of such patients is exceedingly d...
Survival in Elderly Patients Diagnosed With Acute Myeloid Leukemia: A Hospital-Based Study [0.03%]
急性髓系白血病老年患者生存分析：基于医院的数据研究
Diana Marcela Mendoza-Urbano,Maria Elena Tello-Cajiao,Joaquin Rosales et al.
Diana Marcela Mendoza-Urbano et al.
Background: Acute myeloid leukemia (AML) is a hematological neoplasm that is more frequent in elderly patients. The objective of this study was to evaluate elderly patients' survival with de novo AML and acute myeloid leu...
The Impact of Graft CD3+ T-Cell Dose on the Outcome of T-Cell Replete Human Leukocyte Antigen-Mismatched Allogeneic Hematopoietic Peripheral Blood Stem Cells Transplantation [0.03%]
供者CD3⁺T细胞剂量对移植物抗宿主病后补输T细胞的造血干细胞移植结果影响：一项回顾性研究
Khalid Halahleh,Rawan Mustafa,Dania Sarhan et al.
Khalid Halahleh et al.
Background: Data on whether the graft CD3-positive (CD3+) T-cell dose in T-cell-replete human leukocyte antigen (HLA)-mismatched allogeneic hematopoietic peripheral blood stem cells transplantation (PBSCT) influences post...
Mature Type T-Lymphoblastic Leukemia/Lymphoma Presenting With Isolated Central Nervous System Symptomatology in a Patient With Giant Cell Arteritis on Long-Term Steroid Treatment [0.03%]
一名长期使用皮质类固醇治疗的巨细胞动脉炎患者出现成熟T淋巴母细胞白血病/淋巴瘤并伴有孤立性中枢神经系统症状
John Kolton Smith,Xinmin Zhang,Stephen C Machnicki et al.
John Kolton Smith et al.
T-lymphoblastic leukemia/lymphoma (T-ALL/T-LBL) is a malignancy comprised of T-lymphoblasts that can present as one of four clinical subtypes (pro-T, pre-T, cortical T, and mature T). Clinical presentation is typically characterized by leuk...
Case Reports
Journal of hematology. 2023 Feb;12(1):42-48. DOI:10.14740/jh1037 2023
Adverse Hematological and Non-Hematological Events in Patients With Relapsed/Refractory Multiple Myeloma That Are Responsive to Daratumumab, Pomalidomide and Dexamethasone [0.03%]
达雷木单抗、泊马利莫和地塞米松治疗复发难治多发性骨髓瘤患者的血液学和非血液学不良事件
Omar Alkharabsheh,Polina Bellman,Zahra Mahmoudjafari et al.
Omar Alkharabsheh et al.
Background: Daratumumab, pomalidomide, and dexamethasone (DPd) is an effective option for treatment of patients with relapsed/refractory multiple myeloma (RRMM). In this study, we sought to analyze the risk of hematologic...
Transformed Plasmablastic Lymphoma Presenting With Marked Lymphocytosis and Spontaneous Tumor Lysis Syndrome [0.03%]
表现为明显淋巴细胞增多和自发性肿瘤溶解综合征的转化浆细胞样淋巴瘤
Yannis Hadjiyannis,Cecelia Miller,Norris I Hollie et al.
Yannis Hadjiyannis et al.
The clinicopathology entity of plasmablastic lymphoma (PBL), despite broad recognition by the World Health Organization (WHO), represents a diagnostic challenge due to its overlapping features and scarce occurrence. Often, PBL arises in imm...
Case Reports
Journal of hematology. 2023 Feb;12(1):49-58. DOI:10.14740/jh1067 2023