Talal S Al-Qaisi,Berjas Abumsimir,Maher Sughayer et al.
Talal S Al-Qaisi et al.
Background: In Jordan, lung cancer ranks as the second most common tumor, and there is an urgent need to explore the genetic landscape of lung cancer. This study aimed to identify the actionable mutations in lung cancer s...
Comprehensive Investigation of a Tyrosine Kinase Inhibitor-Resistant Gene Zeste White 10 in Hepatocellular Carcinoma [0.03%]
酪氨酸激酶抑制剂耐药基因Zeste白10在肝细胞癌中的综合研究
Qing Ling Huang,Guan Lan Zhang,Qin Yan Su et al.
Qing Ling Huang et al.
Background: Tyrosine kinase inhibitors (TKIs) are first-line therapies for hepatocellular carcinoma (HCC), but the drug resistance restricts the long-term clinical outcomes. This study aimed to investigate the expression ...
Prevalence and Clinical Outcomes of Human Epidermal Growth Factor Receptor 2 Expression in Patients With Advanced Urothelial Carcinoma [0.03%]
晚期尿路上皮癌患者的人表皮生长因子受体2表达的流行病学特征及其临床预后研究
Ivan A Ortiz-Calderon,Luis Felipe Arias-Ruiz,Rita Dorantes-Heredia et al.
Ivan A Ortiz-Calderon et al.
Background: The prognosis for urothelial carcinoma remains poor, with limited therapeutic options, emphasizing the need for further research into targeted therapies. The prognostic and predictive significance of human epi...
Survival Analysis of Anaplastic Thyroid Carcinoma With Various Therapeutic Modalities: Twenty-Seven Years' Experience in a Single Cancer Center [0.03%]
单一癌症中心27年不同治疗方式下间变性甲状腺癌的生存分析经验总结
Putu Anda Tusta Adiputra,I Gede Budhi Setiawan,I Putu Gede Septiawan Saputra et al.
Putu Anda Tusta Adiputra et al.
Background: Anaplastic thyroid carcinoma (ATC) is the most aggressive thyroid gland malignancy. Several consensuses support the concept of multimodal therapy that combines surgery, radiation, chemotherapy, and targeted th...
Impact of 2021 World Health Organization Grading, Peritumoral Edema, and Radiotherapy on the Recurrence of a Grossly Resected Intracranial Meningiomas: A Ten-Year Follow-Up Study [0.03%]
2021年世界卫生组织分级、肿瘤周围水肿和放射治疗对全切颅内脑膜瘤复发的影响：一项十年随访研究
Alaa Alkhotani,Saleh Baeesa,Maryam Alshanqiti et al.
Alaa Alkhotani et al.
Background: The significance of histological grading and peritumoral edema (PTE) in predicting intracranial meningioma recurrence among Saudis is often neglected. This study aimed to evaluate the impact of these factors o...
MicroRNA-155 as Biomarker and Its Diagnostic Value in Breast Cancer: A Systematic Review [0.03%]
微RNA-155作为生物标志物在乳腺癌诊断中的价值：系统综述
Bann Siang Yeo,Wen Xuan Lee,Rozi Mahmud et al.
Bann Siang Yeo et al.
The investigation of microRNAs (miRNAs) for the purpose of identifying biomarkers and new treatments for breast cancer has been gaining traction from scientists in recent years. Of all the miRNAs, miR-155 has been reportedly involved in bre...
Methylation of SOX1 and PAX1 Are Risk Factors and Potential Biomarkers for Cervical Lesions [0.03%]
SOX1和PAX1甲基化是宫颈病变的风险因素及潜在生物标志物
Yan Die Lin,Xiao Yue Li,Li Wei Shao et al.
Yan Die Lin et al.
Background: The correlation between methylation of paired box gene 1 (PAX1) and sex determining region Y-box 1 (SOX1) with human papillomavirus (HPV) infection and the progression of cervical lesions is not well understoo...
Proliferation Inhibited by Genipin in Human Leukemia K562 Cells: Involvement of Uncoupling Protein 2 in Mitochondrial Damage [0.03%]
细胞增殖抑制：苦柯茋通过线粒体通道蛋白2损伤线粒体抑制人K562细胞的增殖作用
Ying Zhou,Rui Sun,Zi Wen Zhang et al.
Ying Zhou et al.
Background: Uncoupling protein 2 (UCP2) is essential for maintaining redox homeostasis and regulating energy metabolism. Abnormal expression of UCP2 has been associated with various tumors, including leukemia. Genipin (GE...
Correlation Between PIK3R1 Expression and Cell Growth in Human Breast Cancer Cell Line BT-474 and Clinical Outcomes [0.03%]
PIK3R1表达与人乳腺癌细胞系BT-474细胞增殖的相关性及其临床意义
Yi-Fang Tsai,Jiun-I Lai,Chun-Yu Liu et al.
Yi-Fang Tsai et al.
Background: While mutations in the PIK3CA gene play important roles in human breast carcinogenesis, PIK3R1 gene alterations are recognized as actionable mutations for clinical cancer treatment. We aimed to elucidate the r...
Expression Profile of Thymidine Kinase Genes in Cervical Squamous Cell Carcinoma Confirmed by Various Detection Methods [0.03%]
多种检测方法确认宫颈鳞癌中胸苷激酶基因表达谱
Cai Xia Liang,Ya Jun Pang,Man Yu Chen et al.
Cai Xia Liang et al.
Background: Thymidine kinases (TKs) are key enzymes involved in DNA synthesis and repair, with alterations in their expression associated with various cancers. Thymidine kinase 1 (TK1) and TK2 are cytosolic enzyme protein...